1. ʻAfa-Lactalbumin
2.Beta-Lactoglobulin
3. Lactoperoxidase (LP)
4.Immunoglobulin G (IgG)
5. Lactoferrin (LF)


ʻO ia ka protein

Loaʻa ka prototein ma loko o ke kino - ma ka ʻāʻī o ka iwi, ka iwi, ka ʻili, ka lauoho, a me ka ʻokoʻa o nā ʻāpana āpau a me ke ʻano. ʻO ia ka hana ʻana o nā huina e hiki ai i nā mana he nui a me nā hemoglobin e hali ana i ka oxygen i kāu koko. Ma ka hapa liʻiliʻi he 10,000 mau ʻōmaʻomaʻo ʻē aʻe e hana iā ʻoe ma ke ʻano a ʻo ʻoe.

Hāʻawi ka Protein i ka ikehu a kākoʻo i kou ʻano a me kāu hana kognitive. ʻO kahi mea momona nui e pono ai no ka kūkulu ʻana, mālama, a me ka hoʻoponopono ʻana i nā io, nā ʻuna, a me nā ʻōnaehana ma ke kino a pau.

He aha nā mea lapaʻau Protein?

ʻO nā pāmaha protote ka puna i hoʻōla ʻia mai ka mea kanu mai nā mea kanu holoholona a mea kanu paha, e like me ka wai hoʻomalu, nā hua hua, ka pā a i ʻole nā ​​pī. Kūkulu ʻia nā kīmaha protein mai nā ʻano kumuwaiwai a ʻike ʻia i nā ʻano ʻano ʻano nui. Ke hoʻohana nei nā kānaka iā lākou e hoʻonui i ka uaua o ka māhina, hoʻomaikaʻi i ka pūnaehana kino holoʻokoʻa a kōkua i ke kū pono ʻana i ka pono o ka protein.

Akā ʻO wai ke ʻano o ka pauna ʻo Protein?

Nui nā ʻano like o nā koho o ka pauka protein ma waho, hiki iā ia ke manaʻo nui i ka manawa. Eia ma lalo iho nei ka 5 maikaʻi kumu puna o ka pauma protein.

1.Alpha-LactalbuminʻO Phcoker

Alpha-lactalbumin he protein whey maoli kūlohelohe nona kahi kaona maoli kūʻokoʻa o nā mea pono āpau a branched-chain amino acid (BCAA), hana ia i ke ʻano kūmina kumu kū hoʻokahi. ʻO ka nui o nā waikina amino nui i ka alpha-lactalbumin he tryptophan a me ka cysteine, me nā BCAA; ka momona, isoleucine a me ka valine.

Ma muli o ka ʻike nui o ka waikawa amino branched-chain (BCAA, ~ 26%), kūikawā ka leucine, alpha-lactalbumin i ke kākoʻo maikaʻi loa a hoʻoulu i ka synt protein protein, a me ke kumu o ka protein kumu kūpono no ka hoʻomaikaʻi ʻana i ke ola olakino a kōkua i ka pale ʻana i ka sarcopenia i ka wā lohi.

2.Beta-LactoglobulinʻO Phcoker

ʻO Beta-Lactoglobulin (ß-lactoglobulin, BLG) ka protein nui o ka whey i ka waiū ruminant a ʻike pū ʻia i ka waiū o nā holoholona ʻē aʻe, akā ʻaʻole i loaʻa i ka waiū kanaka. ʻO Beta-lactoglobulin he protein lipocalin, a hiki ke hoʻopaʻa i nā molekele hydrophobic he nui, e hōʻike ana i kahi kuleana ma ko lākou halihali. Ua hōʻike ʻia nō ka β-lactoglobulin e hiki iā ia ke hoʻopaʻa i ka hao ma nā siderophores a pēlā ka kuleana i ka hakakā ʻana i nā pathogens. ʻO β-Lactoglobulin kahi i waiho like ʻole i nā ʻano hana a me nā mea pono maikaʻi i hana ai i kēia mea hoʻomoʻoniʻoni i mea e pono ai no ka nui o nā meaʻai a me nā noi biochemical.

3.Lactoperoxidase (LP)ʻO Phcoker

ʻO ka Lactoperoxidase kahi enzyme maoli i ʻike ʻia i loko o ka waiū o ka nui o nā mammals, a me nā ʻano wai ʻē aʻe e like me ka waimaka a me ka lawena. Hana ia e like me ka hoʻomehana, hoʻihoʻi i nā ʻoi thiocyanate i mua o ka hydrogen peroxide i loko o ka acid hypothiocyanous. Ka hopena o ka waikawa i ka waiū a me nā huaʻi hypothiocyanate e kū nei me nā hui suphydryl e hoʻohuli i ka metabolabeta o nā huakini. Mālama kēia i nā maʻi i ka hoʻonui ʻana a hiki i ka hoʻonui ʻia ʻana i ka mana kūpono o ka waiū maka.

Lactoperoxidase kaulana ia i nā waiwai antimicrobial a me antioxidant. Wahi a nā noiʻi i paʻi ʻia ma ka Journal of Applied Microbiology, he mau mea antibacterial i kōkua no ka ʻili a hiki ke hoʻopau i nā maʻi huakini. ʻO ka Lactoperoxidase kekahi mea nui i ka hui pū ʻana i nā mea i hoʻohana ʻia e pale ai i ka yeut, nā fungi, nā maʻi a me nā maʻi mai ka ulu ʻana i nā kūleʻa a me nā huahana nani.

ʻO ka Lactoperoxidase kahi glycoprotein me ka hana anti-microbial, hoʻohana ʻia ʻo ia ka mea e hoʻomehana ʻia ana e kōkua i ka hoʻomaikaʻi ʻana i ka hoʻopulapula hoʻonohonoho ʻana a me ka noho ʻana o ka huahana.

4.Immunoglobulin G (IgG)ʻO Phcoker

ʻO ka immunoglobulin G (IgG) ka isotype nui ka nui o ka isotype i loko o ke koko (plasma), ka helu o 70-75% o nā immunoglobulins kanaka (antibodies). Ua wehe ʻo IgG i nā mea hōʻeha a he mea nui ia i ka hoʻomaopopo ʻana o nā hōʻea o nā antigen-antibody e nā leukocytes a me nā maccrophages. E hoʻoneʻe ʻia ʻo IgG i ka pēpē ma o ka plasenta a mālama i ka pēpē a hana ʻoi aku kona pūnaehana ponoʻī.

Hiki i ka immunoglobulin ke hoʻopaʻa i nā microorganisms pathogen a me nā meaʻawaʻī e hana i nā antibodies, hiki ke hoʻomaikaʻi i ka pale ʻana o ka ʻōpiopio.

5.Lactoferrin(LF)ʻO Phcoker

ʻO Lactoferrin he protein e ʻike maoli i ka waiū mai nā kānaka a me nā bipi. Hiki nō hoʻi iā ia ke loaʻa nā ʻano o nā liʻi hou i loko o ke kino e like me ka lawena, nā waimaka, ka lemus, ka pākī. Loaʻa ka Lactoferrin ma ka nui loa i loko o ka colostrum, ke ʻano mua o ka umauma waiū i hana ʻia ma hope o ka hānau ʻana o kahi pēpē. ʻO nā hana nui a Lactoferrin i loko o ke kino e hoʻopili me ka lawe ʻana i ka hao. Mālama pū kekahi ia i ke kaua i nā maʻi.

Lactoferrin He mea nui ia i ka hoʻonui ʻana i nā hana palekana no nā pēpē liʻiliʻi. Hāʻawi ia i nā hana antibacterial a pale aku i ka hana ʻana i nā pēpē kanaka. ʻO LF kahi māhele o ka pahuhopu o ke kino e pale ai i ka pae mucosal, ma muli o kāna hana antimicrobial kiʻekiʻe.

ʻO nā mea kōkua lactoferrin a me ka lactoferrin me nā mea i noiʻi nui ʻia. Lawe kekahi poʻe i kā supplement lactoferrin e kiʻi i nā pono antioxidant a me nā anti-inflammatory.

I ka mahiʻai kumuhana, hoʻohana ʻia ka lactoferrin pauku e kāohi i nā pōʻino i ka wā o ka hōʻoki ʻai ʻana.

Reference:

  1. ʻO Layman D, Lönnerdal B, ʻo Fernstrom J. Nā noi no ka α-lactalbumin i loko o kaʻai o ke kanaka. Nutr Rev 2018; 76 (6): 444-460.
  2. Markus C, Olivier B, Panhuysen G, et al. Hoʻonui ka bovine protein alpha-lactalbumin i ka ratio o ka tryptophan i ka waikaola nui e like me nā ʻaina amino nui, a ma nā mea haʻahaʻa i hoʻonui ʻia i ka hana serotonin, e hōʻemi ana i ka kukū cortisol, a hoʻomaikaʻi i ka ʻuhane ma lalo o ke kaumaha. Am J Clin Nutr 2000; 71 (6): 1536-1544.
  3. ʻO ka pilina o beta-lactoglobulin me ka retinol a me nā momona momona a me kāna hana e like me kahi mea ola olakino e hiki ai i kēia protein: a review.Pérez MD et al. J Dairy Sci. (1995)
  4. Ke wehe nei i ka beta-lactoglobulin ma ka ʻaoʻao o polystyrene nanoparticles: hoʻokolohua a me nā hana hoʻokūkū .Miriani M et al. Nā mea hoʻohui. (2014)
  5. Hoʻololi ka hoʻololi i loko o ka emulsion-bovine beta-lactoglobulin e pili ana i ka proteolysis me ka immunoreactivity.Marengo M et al. ʻO ka Biochim Biophys Acta. (2016)
  6. Nā hana antimicrobial o nā oxidases pālua a me ka lactoperoxidase.Sarr D et al. J Microbiol. (2018) ʻO ka immobilization Lactoperoxidase ma ka nanoparticle kala e hoʻonui i kāna hana antimicrobial.Sheikh IA et al. J Dairy Res. (2018)
  7. Lactoperoxidase, kahi Protein Milk Antimicrobial, ma ke ʻano he mea hoʻomohala a hoʻomōiwi o ka lāʻau Hinesocyclic Carcinogenic ma Breast Cancer.Sheikh IA et al. Resikecer Res. (2017)
  8. ʻO ke ʻano nui o ka ʻōnaehana Lactoperoxidase ma ke olakino olakino: Ka Hoʻohana a me ka Pono i nā huahana Hyalene Oral. Magacz M, Kędziora K, Sapa J, Krzyściak W. Int J Mol Sci. 2019 Mar 21
  9. Nā Lactoferrin-piha i ka immunocomplex ma waena o nā hopena antitumor ma ka hoʻoponopono ʻana i ka macrophages e pili ana i ke tumuhila i ka M1 phenotype.Dong H, Yang Y, Gao C, Sun H, Wang H, Hong C, Wang J, Gong F, Gao XJ Immunother Cancer. 2020 Mar
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  11. Nā Līnekini Lactoferrin: ʻO ka palekana, ka koho, a me ka ākea ākea o nā hana.Cutone A, Rosa L, Ianiro G, Lepanto MS, Bonaccorsi di Patti MC, Valenti P, Musci G.Biomolecules. 2020 Mar 15
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