Urolithin A （1143-70-0） wikiō
ʻO Urolithin A （1143-70-0）hoakaka
| Product Name | Urolithin He pauka |
| Hawaiian Name | 3,8-dihydroxy-6H-benzo [c] chromen-6-one;
3,8-Dihydroxy-6H-dibenzo (b, d) pyran-6-one; 3,8-Dihydroxyurolithin; 3,8-dihydroxybenzo [c] chromen-6-one; 6H-Dibenzo [b, d] pyran-6-one, 3,8-dihydroxy-; 3,8-Hydroxydibenzo-alpha-pyrone; |
| Kāleka CAS | 1143-70-0 |
| InChIKey | RIUPLDUFZCXCHM-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1O)C(=O)OC3=C2C=CC(=C3)O |
| hakakino F'Oula | C13H8O4 |
| hakakino Wʻewalu | 228.2 g / mole |
| Monoisotopic Mass | 228.042259 g / mole |
| ʻO ka helu kau | 340-345 ° C |
| ʻO ka paila | 527.9 ± 43.0 ° C (Manaʻo ʻia) |
| Flash Point | 214.2ºC |
| ʻO ka Halifa-Ola | Aia ʻo Urolithin A i ka mimi a hiki i 48 mau hola ma hope o ka hoʻohana ʻana i ka wai pomeraite. |
| kala like 'ole | Keʻokeʻo i ka beige |
| Solakino | DMSO: 20 mg / mL, maopopo |
| Ska hoʻokele Tka mahana | 2-8 ° C |
| Apaukū | Hoʻohana ʻia ma ke ʻano he mea hoʻohui meaʻai a me ka huahana anti-kūnewa, hiki ke hoʻohana ʻia e hōʻemi i ka lī a me ka hakakā ʻana i ka maʻi ʻaʻai; |
Reference:
[1] Garcia-Muñoz, Cristina; Vaillant, Fabrice (2014-12-02). "Metabolic Fate of Ellagitannins: Nā hopena no ke olakino, a me nā ʻike noiʻi no nā meaʻai hana hou Innovative". Nā loiloi koʻikoʻi i ka Science Science a me ka Nutr 54 (12): 1584–1598. hana: 10.1080 / 10408398.2011.644643. ISSN 1040-8398. PMID 24580560. S2CID 5387712.
[2] Ryu, D. et al. Hoʻokomo ʻo Urolithin A i ka mitophagy a hoʻolōʻihi i ke ola i C. elegans a hoʻonui i ka hana muscle i nā rodents. ʻO Nat. Med. 22, 879-888 (2016).
[3] "Hoʻomaopopo ʻo FDA GRAS GRN Helu 791: urolithin A". ʻO US Food and Drug Administration. 20 Kekemapa 2018. Loaʻa iā 25 ʻAukake 2020.
[4] Singh, A. Andreux, P. Blanco-Bose, W .; Ryu, D.; Aebischer, P. Auwerx, J. Rinsch, C. (2017-07-01). "Palekana ʻo oral urolithin A i kahi palekana a hoʻololi i nā biomarkers muscle a me mitochondrial i ka ʻelemakule". ʻO ka hana hou i ka wā ʻelemakule. 1 (suppl_1): 1223–
[5] Heilman, Jacqueline; Andreux, Pénélope; Tran, Nga; Rinsch, Chris; Blanco-Bose, William (2017). "Ka loiloi palekana o ka urolithin A, kahi metabolite i hana ʻia e ka microbiota ʻōpū o ke kanaka i ka lawe ʻana i ka papaʻai o ellagitannins a me ellagic acid". Mea Toxicology Mea ʻai a me kemika. 108 (Pt A): 289– doi: 10.1016 / j.fct.2017.07.050. PMID 28757461.
