Pākīwī kaona wikiō
Kaʻike Base
| Product Name | ʻO Tadalafil pau |
| Hawaiian Name | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione |
| Brand Name | Cialis, Adcirca |
| Kōpana Drug | PAH, PDE-5 Hoʻonāukiuki; Nā Hoʻopilikia Hoʻopiʻi Enzyme o ka Phosphodiesterase-5 |
| Kāleka CAS | 171596-29-5 |
| InChIKey | WOXKDUGGOYFFRN-IIBYNOLFSA-N |
| hakakino F'Oula | C22H19N3O4 |
| hakakino Wʻewalu | 389.4 |
| Monoisotopic Mass | 389.138 g / mole |
| Hoʻolaha Pʻo kaʻaila | 298-300 ° C |
| Fkū hou Pʻo kaʻaila | 2 ° C |
| ʻO ka Halifa-Ola | 17.5 hola |
| kala like 'ole | ʻO ka White i ka White-Cyrstalline Solid |
| Solakino | Wailana ma DMSO (78 mg / ml ma 25 ° C), methanol, wai (<1 mg / ml ma 25 ° C), dichloromethane, a me ka etanol (<1 mg / ml ma 25 ° C) |
| Ska hoʻokele Tka mahana | E mālama i ka mahana o ka lumi ma waena o 59 ° F a me 86 ° F (15 ° C a me 30 ° C). Mai mālama i kēia lāʻau i nā wahi momona a pulu hoʻi. |
| Tadalafil Apaukū | Nā pāpuni pākuʻiʻo Tadalafil, Nā lole moe, Kapala Kapala, a pēlā aku. |
Pauka Tadalafil
ʻO ka maʻi Erectile kahi maʻi hōʻeuʻeu maʻamau i nā kāne e pili ana i ka 52 pākēneka o nā kāne ma mua o 18 mau makahiki, ma ka honua holoʻokoʻa. Hoʻololi ka ikaika, hana pinepine ʻia ka erectile e ka hōʻemi ʻia o ke kahe o ke koko i nā kīʻaha koko, ʻo ia ka hana nui i ka hana o kahi kūkulu.
ʻO ka maʻi Erectile kahi mālama piha a mālama ʻia me nā lāʻau ʻokoʻa e kuhikuhi ana i nā enzymes loea i ka paia o nā kīʻaha koko. ʻO kekahi o nā lāʻau i ikaika loa no ED ʻo Tadalafil pauma me kahi hapalua o ke ola o 17.5 mau hola.
He aha ka pauka Tadalafil?
Pili ʻo Tadalafil Powder i ka papa stimulants moekolohe o ka lāʻau ʻoiai he lāʻau ia i hoʻolālā ʻia no nā kāne ma mua o 18 mau makahiki, e loaʻa nei i ka maʻi erectile. ʻO Tadalafil, a i ʻole (6R-trans) -6- (1,3-benzodioxol-5-yl) -2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1 ＇, 2＇: 1,6 , 3,4] pyrido [1,4-b] indole-XNUMX-dione kahi lāʻau like me Sildenafil a me Viagra, i ka hana, akā ʻokoʻa i ke ʻano. ʻOkoʻa ʻo Tadalafil mai ka lāʻau lapaʻau erectile maʻamau, Viagra, i ka ikaika no ka mea ʻoi aku ka ikaika a me ka maikaʻi ma mua o ka hope.
ʻO Tadalafil Powder kahi lāʻau lapaʻau PDE5 mea hōʻoki, ʻo ia hoʻi ka mea i pahuhopu i ka enzyme PDE5 i loaʻa i nā hunaola maʻemaʻe o nā kīʻaha koko peni. ʻO ka hana kaohi o ka lāʻau lapaʻau he mea maikaʻi loa ia e like me ke kumu nui o ka enzyme e hoʻokumu i ka vasoconstriction, i loko o nā kīʻaha koko penile, nā hopena i ka hōʻemi ʻia o ke kahe o ke koko a me ka hopena o ka erectile.
Hana ʻia ʻo Tadalafil Powder e Pharmax Lifesciences a hiki ke hoʻohana ʻia no ka mālama ʻana i nā mea ʻoi aku ma mua o ka hana ʻole o erectile. Kau ʻia ʻo Tadalafil Powder i nā kāne e ʻeha nei i ka hyperplasia prostatic benign a me ka hypertension arterial pulmonary. Eia nō naʻe, maikaʻi ʻole ʻo Tadalafil Powder i ka mālama ʻana i nā maʻi hōʻeuʻeu ʻē aʻe i nā kāne a me nā wahine.
Nā ʻano o Tadalafil
ʻO Tadalafil kahi mea hoʻopuka PDE5 ikaika, hiki ke loaʻa i nā ʻano like ʻole a me nā hana, e hoʻomālamalama ana i ka hoʻohana ʻana no nā mea maʻi. Loaʻa ka lāʻau i ke ʻano o nā pila a i ʻole nā capsule, me ke ana he 5 mg, 10 mg, a me 25 mg. He mea nui e hoʻomaopopo he ʻokoʻa ke ana o Tadalafil ma muli o ka ʻoihana hana.
Loaʻa ʻo Tadalafil i ka pauka, ʻoiai e kūʻai nui ʻia ia no ka hana ʻoihana. ʻO kēia ke kumu nui ma hope o Tadalafil Powder kūʻai nui kūʻai nui ʻia me kēia ʻano o ka lāʻau. Kūʻai kūʻai pinepine ʻia kēia palapala i nā pahu o 25 kg a 50 kg, kaukaʻi ʻia i ka koina nui.
ʻO ka mahele maʻamau no ka pauka Tadalafil, e hoʻomaka me 10 mg. ʻO ka mea ʻoi loa, ma loko o 24 mau hola, he 20 mg, a ʻaʻole i hōʻike ʻia i ka ʻoi loa o kēia ana.
Palekana kēia lāʻau no ka ʻai ʻana o kānaka ma muli o ka loaʻa ʻana o ka ʻae ʻia e ka FDA a ʻae ʻia mai nā luna ʻĀina, Kanada, Australia, a me British Health. Ua ʻae ka FDA i ka hoʻohana ʻana o nā lāʻau Tadalafil i ka makahiki 2002, a ma hope koke iho, ua ʻae ʻia e FDA kekahi hoʻohana puʻuwai.
Hoʻopiʻi ka hale hana mea hana lepo ʻo Tadalafil e hana i ka lāʻau lapaʻau wale nō me ka pololei loa. Manaʻo nui nā mea hana i ka palekana o ke kanaka, i mōakāka nui ʻia i ka ikaika, palekana, a me ka pono o ka huahana hope loa.
Pehea e hana ai ʻo Tadalafil Powder?
Aia ʻo Tadalafil Powder iā Tadalafil, kahi mea hoʻopili inhibitor PDE5 i noiʻi mua ʻia a hana ʻia e GlaxoSmithKline ma hope o ka loaʻa ʻana o Sildenafil, kahi hui like. ʻO Sildenafil, ma ka ʻaoʻao ʻimi, ua ʻimi mua ʻia ma ke ʻano he lapaʻau no ka angina a me ke kiʻekiʻe o ka hypertension akā ua holoi ʻia ka noiʻi holoʻokoʻa ma hope o nā hopena i kū ʻole i ka wā mua o ka noi. Eia nō naʻe, ma ka loiloi ʻana, ua ʻike ʻia e hiki paha iā Sildenafil ke hana i nā kūkulu inā hoʻonāukiuki maikaʻi ʻia nā mea maʻi.
ʻOiai ʻo sildenafil kahi mea kāohi PDE5, ua hoʻoholo ʻo GlaxoSmithKline e hana i kahi hulina ākea i nā mea hoʻohui me kahi ʻano hana like e like me Sildenafil. Ua alakaʻi kēia noiʻi i ka loaʻa a laila ka hoʻomohala ʻana o Tadalafil.
ʻO Tadalafil kahi mea hoʻopuka PDE5 ikaika me ka hapalua o ke ola o 17.5 mau hola e lawe ana ma kahi o 96 mau hola e holoi loa i waho o ke kino o ke kanaka. Ke hoʻohālikelike ʻia i ka pila polū maʻamau, ʻo Viagra, ka mea e hoʻohana wale ʻia no 3 mau hola a 4 mau hola ma hope o ka ʻai ʻana, puka ʻo Tadalafil ma luna.
ʻO ka papa hana nui o ka hana o ka lāʻau lapaʻau ke kāohi nei i ka enzyme PDE5 e kū nei i nā huna momona o nā kīʻaha koko penile. ʻO ka pāpā ʻana o kēia enzyme nā hopena i ka vasodilation a i ka hopena, hoʻonui ʻia ke kahe o ke koko ma o nā kīʻaha koko, i hoʻopuni ʻia e corpus cavernosa. ʻO kēia mākala o ka peni, ke waiho ʻia ma lalo o ke kanana e ka hoʻonui ʻia o ke kahe o ke koko, kaomi ʻia i kahi kū i luna, kahi i kapa ʻia he kūkulu.
Eia nō naʻe, pololei nā mākala penile, corpus cavernosa, pono e hoʻomaha mua i hiki i nā kīʻaha koko ke hoʻonui a loaʻa i kahi kiʻekiʻe o ke koko. ʻO kēia hoʻomaha ʻana o nā mākala maʻalahi ka hopena o ka pāpā ʻana i ka enzyme PDE5, ʻoiai ma ke ʻano ʻole. ʻO ka pāpā ʻia ʻana o PDE5 nā hopena e hoʻonui ai i ka nui o Guanosine MonoPhosphate a i ʻole GMP, he mea nui ia no ka hoʻomaha ʻana o nā mākala maʻalahi, e like me corpus cavernosa.
Eia naʻe, ʻaʻole kēlā wale nō ka hoʻohana a me ka hana o ka hana o Tadalafil Powder. Hoʻohana ʻia ka lāʻau lapaʻau wale no ka hyperplasia prostatic maikaʻi, kahi maʻi urinary i hoʻokumu ʻia e ka hoʻonui ʻia ʻana o ka gland prostate a me ka hōʻike ʻana i ka urination ʻeha. ʻO ke ʻano o ka hana no ka mālama ʻana i ka momona prostate i hoʻonui ʻia ma o ka hoʻonui ʻia o nā kiʻekiʻe o GMP i nā ʻāpana puʻupuʻu momona. Hoʻomaha ka hoʻomaha ʻana o kēia mau pūnaewele i ka hele maʻalahi o ka mimi a pale i ka paʻa ʻana o ka mimi a me ka ʻeha.
Hoʻomaopopo pū ʻia ʻo Tadalafil Powder no ka pulmonary arterial hypertension, ʻoiai ka hopena PD PD e hōʻemi ʻole ana i ke kahe o ke koko akā hoʻoliʻiliʻi hoʻi i ke kahe o ke koko, kahi mea maikaʻi loa i ka mālama ʻana iā PAH.
He aha ka mea e hiki ai ke hoʻohana ʻia ka Powder Tadalafil?
Hoʻohana ʻia ʻo Tadalafil Powder no ka mālama ʻana i nā ʻano aʻe:
- ʻO ka haʻahaʻa Erectile
- ʻO Benign Prostatic Hyperplasia
- ʻO ke kiʻekiʻe kiʻekiʻe o ka pulmonary Arterial
ʻOiai ke mālama ʻia nei ka noiʻi e pili ana i ka hoʻohana hou ʻana o ka lāʻau, i kēia manawa ua kuhikuhi ʻia ia i nā kāne ma mua o 18 mau makahiki, e ʻeha nei i kekahi o nā maʻi i ʻōlelo ʻia ma luna. ʻO ka maʻamau, hoʻohana ʻia ka lāʻau no ka mālama ʻana i ka hana erectile.
Nā pono o ka Tadalafil Powder
He nui nā pōmaikaʻi ʻo Tadalafil ma kāna iho a ke hoʻohālikelike ʻia i nā mea kāohi PDE5 ʻē aʻe i ka papa o nā lāʻau stimulants wahine. He ikaika a lōʻihi loa kēia lāʻau lapaʻau no ka mea he 36 mau hola e hoʻomaʻemaʻe ʻia mai ka ʻōnaehana, ʻaʻole hiki ke ʻike ʻia ma hope o 96 mau hola. Ua ʻike ʻia nā hopena o ka lāʻau a ʻike ʻia ma kahi o 20 mau minuke i 60 mau minuke ma hope o ka ʻai ʻana, a paʻa mau ka pauka Tadalafil ma kahi o 3 mau hola a 4 mau hola ma hope. He mea nui e haʻi i ka hana o ka lāʻau ʻaʻole like i kekahi ʻano me ka lōʻihi o ke kūkulu ʻana.
ʻAʻole hiki i ka Tadalafil Powder ke hana i nā kūkulu kūlohelohe a pono i ka hoʻonāukiuki ʻana i ka moekolohe a me ka hoʻonāukiuki ʻana e pono ai i ka hana ʻana i kūkulu. Inā hāʻawi ʻia ka hoʻonāukiuki i ka moekolohe i loko o nā hola ʻehā ma hope o kaʻai ʻana o ka lāʻau, hiki i ka lāʻau ke hana i kahi kūkulu a hoʻoliʻiliʻi i nā ʻōuli o ka hana ʻole o erectile.
He maikaʻi loa kēia lāʻau hoʻoweliweli wahine i ka mālama ʻana i ka hana erectile ma ke ʻano he hopena o ka hana lōʻihi, a lilo ia i lāʻau lapaʻau i wae ʻia no nā mea he nui e ʻeha ana i ka hana erectile a me ka hyperplasia prostatic benign. Hiki ke hoʻohui pū ʻia ʻo Tadalafil Powder me Tamulsin, kahi lāʻau lapaʻau ikaika ʻē aʻe no ka mālama ʻana i ka hyperplasia prostatic benign ʻoiai ke aʻo ʻia nei a kālailai ʻia ka maikaʻi o kēia hui lāʻau.
Hana kūpono o Tadalafil Powder
ʻO Tadalafil Powder, e like me ka mea i ʻōlelo ʻia ma luna, hoʻomaka pinepine ʻia ma 10 mg ma ke ʻano he mahele haʻahaʻa e hiki ai. Ma hope o hoʻokahi pule i ka hoʻohana ʻana i ka lāʻau, hoʻemi ʻia ka hoʻonui ʻana, hoʻonui ʻia, a mālama ʻia paha ma nā pae like e pili ana i nā hopena. Eia nō naʻe, he mea nui e hoʻomanaʻo i kēia lāʻau lapaʻau he lāʻau lapaʻau wale nō ia e hoʻohana wale ʻia ai inā pono. Hoʻohana wale ʻia ia i hoʻokahi manawa ma nā hola 24 i ʻole e hoʻonui i nā hopena o ka lāʻau.
ʻO ka makaʻu o kahi lāʻau i hala ʻole no kahi lāʻau e pono ai ke lawe ʻia ke pono inā kokoke he ola akā, he mea nui e wehewehe i nā alakaʻi no kahi lāʻau i hala. ʻO kēia no ka mea ua kuhikuhi ʻia ka lāʻau no ka hoʻohana ʻana i kēlā me kēia lā, ma ka liʻiliʻi ʻekolu mau manawa i ka lā ke hoʻohana ʻia no ka mālama ʻana i ka hanu pulmonary artery a me ka hyperplasia prostatic benign. Inā loaʻa kahi lāʻau i hala ʻole, ʻoi aku ka maikaʻi o ka hōʻalo ʻana i kēlā hana maʻa loa, a ma lalo o nā hanana i ʻole e uku ʻia kahi lāʻau i hala me kahi pālua pālua i ka manawa aʻe. Hiki i kēia ke alakaʻi i nā hopena hoʻolōʻihi a lōʻihi ʻole i loaʻa ka hopena e hopena i nā pilikia ʻaneʻane make.
ʻO wai ka mea pono ʻole e hoʻohana i ka pauka Tadalafil
He mau pono like ʻole a hoʻohana ʻia ʻo Tadalafil Powder akā hana ʻia ia no ke kāne kāne, keu hoʻi i nā makahiki 18 a ʻoi. ʻAʻole pono e lawe ʻia nā lāʻau e nā wahine a me nā keiki no ka mea ʻoi aku ka nui o ka hopena o ka hoʻomohala ʻana i nā ʻano ʻaoʻao āpau a me nā pilikia e pili ana i ka hoʻohana ʻana o Tadalafil Power.
ʻAʻole pono nā lāhui aʻe e lawe i ka Tadalafil Powder, a i ʻole e kūkākūkā me kā lākou kauka ma mua o ka hoʻomaka ʻana i kekahi lāʻau i pili i ka papa lāʻau lapaʻau inhibitors PDE5:
- ʻO ka poʻe me ka mōʻaukala o ka hana ʻoki ʻana i loko o nā mahina ʻekolu i hala
- ʻO ka poʻe me ka mōʻaukala o nā hanana puʻuwai i nā mahina ʻekolu i hala aku nei i ʻeono mau mahina
- ʻO ka poʻe me ke kiʻekiʻe kiʻekiʻe a me ka hyperlipidemia
- ʻO ka poʻe me nā maʻi hōʻeha
- ʻO ka poʻe me retinitis pigmentosa
- ʻO ka poʻe me ka hemophilia a i ʻole nā maʻi koko like
- ʻO ka poʻe me myeloma he nui, a i ʻole leukemia
- ʻO ka poʻe me ka maʻi ʻōpū
- ʻO nā kānaka me ka moʻolelo o ka hahau a i ʻole me ka nui o ka makaʻu i ka maʻi kō
ʻAʻole ʻae ʻia kēia poʻe e lawe iā Tadalafil no ka mea hiki i kā lākou mau lāʻau i kēia manawa ke hui pū me ka lāʻau, a laila hopena i nā pilikia hoʻoweliweli. I kekahi mau hihia, ʻoi aku ka maʻalahi o ke kino o kēia mau mea maʻi i nā hopena maʻamau a ʻano ʻole ʻole o ka lāʻau akā ʻoi aku ke kiʻekiʻe o nā pilikia ma mua o ka maʻamau.
Nā hopena ʻē aʻe o ka Tadalafil Powder
ʻO Tadalafil Powder, e like me ka nui o nā lāʻau, he mau hopena ʻaoʻao e pili pū me kāna hoʻohana. Eia nō naʻe, ʻaʻohe o lākou e koʻikoʻi, hoʻololi i nā hana o kēlā me kēia lā, a hoʻoweliweli paha i ke ola. ʻO ka ʻoiaʻiʻo, ʻo ka hapanui o lākou e hoʻonā iā lākou iho a ʻaʻole koi i ka lāʻau lapaʻau.
Loaʻa nā hopena ʻaoʻao maʻamau o Tadalafil, akā ʻaʻole kau palena ʻia i:
- ʻO ka ihu nui
- Headaches
- ʻO Dyspepsia
- Eha ka' ōpū
- Flushing; mehana a me ka ʻula o ka ʻili
- Tinnitus; kani kani mau i ka pepeiao
- Nā pilikia lohe
- ʻO ka'ikepō Blurry
- Loaʻa o ka hihiʻo
- Priapism
ʻOi aku ka koʻikoʻi o ka hopena hope a kuhikuhi i kahi kūkulu lōʻihi a ʻeha hoʻi i hala, ʻoi aku ma mua o ʻehā mau hola. I kēlā mau hanana, koi ʻia e ʻimi koke i ke kōkua lapaʻau no ka mea ʻoi aku ke koʻikoʻi, ʻoiai he kakaikahi, ka hopena o ka hoʻohana ʻana o Tadalafil.
Mai ka ʻOkakopa o 2007, koi aku ʻo FDA i nā ipu lāʻau hoʻomake PDE5 āpau e hoʻopili i kahi lepili hōʻailona e hōʻike i nā mea hoʻohana i ka hiki i kēia mau lāʻau ke hana i kahi manawa no ka lohe koke ʻana. ʻO kēia hoʻoholo a ka FDA ka hopena o nā hoʻopiʻi he nui no ka nalo ʻana o ka lohe i nā mea maʻi e hoʻohana ana iā Tadalafil a i ʻole nā lāʻau like i hoʻopaʻa inoa ʻia me ka FDA, e koi ana iā lākou e kālailai pono i ka pilikia. Ua ʻike ka noiʻi a FDA i ka nalo ʻana he hopena koʻikoʻi ia o TAdalafil i manaʻo lākou e hoʻomaopopo ʻia nā mea maʻi āpau, i nā ʻōlelo maopopo, i hiki ai iā lākou ke hoʻoholo i ka hoʻoholo.
ʻO ka nalo ʻana o ka hihiʻo kahi hoʻopiʻi hou e pili pū ana me ka hoʻohana ʻana o Tadalafil a ke nānā ʻo FDA i kēia mau hoʻopiʻi, ua ʻike ʻia ka hopena o kēia hopena i ka poʻe maʻi e ʻeha nei i ka maʻi o ka maka, ʻo ia hoʻi ʻo neuropathy optic ischemic anterior mua a me NAION. Ma muli o ka loaʻa ʻole o kahi kumu pololei a me ka hopena i loaʻa e ka FDA, ʻaʻohe hōʻailona hōʻailona e pili ana i ka nalo ʻana o ka hihiʻo ma luna o ka pauka Tadalafil a i ʻole nā mea ʻoki ʻoki ʻē aʻe PD PD.
Nā hana laʻau maʻamau me ka pauka Tadalafil
ʻAʻole pono e lawe pū ʻia kekahi mau lāʻau i hiki ke launa pū me kēlā me kēia hopena e hopena ai i ka hopena o nā mea ʻelua, ka hopena i hoʻonui ʻia o nā mea ʻelua, a i ʻole ka hoʻonui ʻana i nā hopena maikaʻi ʻole o nā lāʻau ʻelua.
ʻO Tadalafil Powder kekahi lāʻau e pono ʻole e lawe pū ʻia me nā lāʻau aʻe.
- Nā Antacids: Hana pū kēia mau lāʻau me Tadalafil e like me ka hopena o ka hoʻemi ʻana i ka pono o ka lāʻau hope, ʻoiai ʻaʻole maopopo ka ʻōnaehana kikoʻī. Eia nō naʻe, he mea nui e aʻoaʻo aku i nā mea maʻi e pili ana i ka launa pū ma waena o kēia mau lāʻau ʻelua, ʻoiai ʻo ka lāʻau mua ka lāʻau lapaʻau maʻamau o ka home.
- Nā Inhibitors PDE5: ʻO ka hoʻohana ʻana i nā lāʻau me kahi ʻano like o ka hana e like me ka hiki iā Tadalafil ke hopena i ka piʻi nui o ke kahe o ke koko a me ka hoʻoliʻiliʻi ola i ke kaomi koko. ʻO ka hoʻohuihui ʻana i nā mea kāohi PDE5 ʻokoʻa a i ʻole ka lawe ʻana i ka lāʻau pālua o ka lāʻau like i hiki ke hopena i nā pilikia ma mua o nā keu keu.
- ʻAlekohola: ʻO ka lawe ʻana i ka pauma Tadalafil me ka wai ʻona ʻaʻole hiki ke hana i nā pilikia kūikawā akā hiki i ka hopena ke hoʻonui i ka ikaika o nā hopena ʻaoʻao. Kūleʻa paha lākou i ka hanana akā ke hoʻoikaika ʻia, hiki ke lilo i mea ʻole a koi paha i ke kōkua olakino.
- Nā Nitrates: hoʻohana ʻia kēia mau lāʻau no ke kumu o ka naʻau a ʻo kā lākou hana nui e hoʻonui i ke kahe o ke koko ma o nā kīʻaha koko e ka hopena vasodilatory iā lākou. Ua like kēia ʻano hana me kā Tadalafil, no laila ke hoʻohui ʻia o nā lāʻau ʻelua i ka hopena o nā hopena maikaʻi ʻole o nā lāʻau ʻelua.
- Anti Hypertensives: ʻO ke kumu o ka like o kēia me ka nitrates. Hana nā anti hypertensives a me Taladafil i ka hoʻohaʻahaʻa ʻana i ke kahe o ke koko e nā kīʻaha vasodilating, a inā e hui pū ʻia, e hopena i ke kahe o ke kahe o ke koko i hiki ke hopena i ka make, inā ʻaʻole mālama ʻia.
- Nā Inducers CYP3A4: ʻO CYP3A4 ka enzyme e pili ana i ka excretion o ka hui Tadalafil mai ke kino ma hope o ka lawelawe ʻana i kāna kumu. Eia nō naʻe, ʻo kahi lāʻau lapaʻau e hoʻonui i nā hopena o kēia enzyme e hopena i ka hoʻonui ʻia o ka excretion o Tadalafil, ʻoiai ma mua o ka hiki ke hoʻokō i kāna kumu. Hoʻolilo kēia i ka hope i mea ʻole a makehewa.
- CYP3A4 Inhibitors: ʻO nā lāʻau āpau e kāohi i ka hana o ka CYP3A4 enzyme e hopena i ka excretion o Tadalafil e waiho iā ia i loko o ka ʻōnaehana kanaka ma mua o ka pono. ʻAʻole pono kēia hopena hoʻolōʻihi a hiki ke lilo i makaʻu loa ma ke ʻano holoʻokoʻa, ʻo ia ke kumu e hōʻalo ai i ka hui ʻana o kēia mau mea ʻelua i nā koina āpau.
- Hoʻokumu kēia mau lāʻau i ka vasculature o nā ake māmā, e ʻimi ana e hōʻemi i ke kaomi o ke koko e kahe ana i loko. Eia nō naʻe, ʻo ia kekahi o nā hopena maikaʻi a me nā hoʻohana o Tadalafil. ʻO ka lawe pū ʻana i kēia mau mea ʻelua ke hopena i ke kahe o ke kahe haʻahaʻa o ke kō, a he mea hiki ke make inā ʻaʻole i kūpono a mālama ʻia i ka manawa kūpono.
Aia ma hea kahi e kūʻai aku ai ʻo Tadalafil Powder?
ʻOi aku ka nui o nā kālepa kalepa ʻo Tadalafil Powder ma mua o nā kūʻai kūʻai liʻiliʻi e like me ke kūʻai maʻamau ʻana i ka nui mai ka hale hana mea hana ʻo Tadalafil Powder. ʻO ka maʻamau, kūʻai pinepine ʻia nā lāʻau o ia ʻano pilikino ma ka pūnaewele no ka mea hāʻawi ia i nā mea maʻi me ka noʻonoʻo a me ka pilikino e pono ai lākou. Loaʻa ka lāʻau i ʻaneʻane i nā hale kūʻai lāʻau kūloko a me ka pūnaewele akā pono i nā mea maʻi e loaʻa kahi kauka e hiki ai ke kūʻai aku.
ʻImi hou a me ka ʻikepili
Ke noiʻi mau ʻia nei ʻo Tadalafil a aʻo ʻia e loiloi i kekahi hoʻohana kūpono o ka lāʻau. ʻO Tadalafil kahi kī nui i loko o nā lāʻau ʻokoʻa he nui, ke kūʻai ʻia aku nā mea āpau ma lalo o nā inoa inoa ʻokoʻa, ka hapanui no nā maʻi e like me ka hana erectile, hyperplasia benign prostatic, a me ka hanu kiʻekiʻe. Eia nō naʻe, aia kekahi mau noiʻi ʻokoʻa i hōʻike ʻia i kā lākou mahele mua e hōʻike ʻia ʻo Tadalafil, i ka wā e hiki mai ana, no nā maʻi ʻē aʻe pū kekahi.
ʻO kekahi o nā noi nui e hana ʻia ma Tadalafil e nānā i kona pono a me ka palekana inā hoʻohana ʻia i kēlā me kēia lā e nā mea maʻi e ʻeha ana i ka hana erectile. Ua paʻi ʻia ke aʻo ʻana ma loko o kahi puke ola no Indonesian Health, a ma muli o ke kālailai ʻana o nā kānaka noiʻi i nā puke mai nā ʻikepili uila, ua hoʻoholo ʻo ia e hoʻohana ana iā Tadalafil i hoʻokahi manawa i ka lā e ʻoi aku ka maikaʻi i ka mālama ʻana i ka hana erectile ma mua o ka hoʻohana wale ʻana i ka lāʻau i ka wā e pono ai.
ʻO ke kumu o ke koʻikoʻi o kēia noi ʻana he mana ia e hoʻololi i nā kuʻina lapaʻau no ka hana erectile. Eia nō naʻe, pono e hana hou i nā noiʻi hou ma mua o ka hiki ke hoʻololi i nā hoʻolālā mālama.
ʻO ka noiʻi ʻē aʻe i loko o Tadalafil ka pahuhopu e repurpose i ka wahine stimulant drug, me kahi lāʻau e pili ana i ka papa like, ʻo vardenafil, e hoʻohana ʻia i ka mālama ʻana i nā maʻi iwi. ʻO nā maʻi iwi ma aneʻi e pili ana i nā maʻi kahi e holo ai ka osteoclast a i ʻole nā iwi luku iwi i ka wikiwiki kiʻekiʻe a me ka maikaʻi i kūlike ʻole i ka hana o ka osteoblast a i ʻole nā iwi hana iwi. ʻO kēia ka hopena i ka hoʻemi ʻia o ka iwi iwi i hiki ai i nā mea maʻi ke maʻalahi i nā haki pathologic.
ʻO ka mahele vivo o ke aʻo ʻana i hōʻike ʻia ʻaʻole hiki i kēia mau lāʻau ʻelua ke hoʻonui wale i ka hana o ka osteoblast akā i ka manawa like e hoʻemi i ka hana o osteoclasts. Hiki i nā lāʻau ke hana i kēia no ka mea ʻo ke ala PDE5A ke kī i ka hana ʻana i ke kaulike o nā ʻāpana ʻelua. ʻO ke ala like ka mea i kau ʻia e nā lāʻau no ka mālama ʻana i ka hana erectile. Ma hope o ka hoʻopili ʻana i nā manaʻo in vivo e pili ana i nā hiʻohiʻona holoholona e nā mea noiʻi e alakaʻi nei i kēia noi, ua ʻike ʻia he mau koho kūpono nā lāʻau ʻelua no ka mālama ʻana i kahi iwi iwi maikaʻi. Eia nō naʻe, pono e mālama hou i nā noiʻi e pili ana i nā hopena o nā lāʻau ʻelua i ka iwi iwi o nā kānaka.
ʻO kahi meta-analysis i paʻi ʻia ma ka Endocrinology Journal i hoʻohālikelike ʻia i ka pono o ka mālama ʻana ʻo tadalafil, mālama tamsulosin, a me tamsulosin a me ka mālama ʻana ʻo tadalafil i ke kōkua ʻana i ka kipaku ʻia ʻana o nā pōhaku urethral. ʻO ka pahuhopu o ke aʻo ʻana ʻaʻole wale ia e ʻike i nā therapist hoʻohui hou e kōkua i nā mea maʻi me nā pōhaku ureteral akā e nānā pū i ka palekana o kēia mau papa hana.
ʻO ka hoʻohana wale ʻana o ka tadalafil a i ʻole ka tadalafil me tamsulosin nā koho ʻelua i ʻike ʻia he keu kūpono a liʻiliʻi paha e hana i kahi hopena maikaʻi ʻole. Eia kekahi, hiki i nā hopena analgesic o Tadalafil ke hoʻonā i ka ʻeha o ka hapanui o nā mea maʻi me nā pōhaku ureteral ke ʻike ʻoiai ka lāʻau e kōkua i ka kipaku ʻana i ka pōhaku mai ka ʻōnaehana.