Meclofenoxate (Centrophenoxine) (51-68-3)

Meclofenoxate (Centrophenoxine) (51-68-3) wikiō

ʻO ka paukū Meclofenoxate (Centrophenoxine) Snāʻike

ʻO ka ʻike meclofenoxate (Centrophenoxine)

ʻO Meclofenoxate (Centrophenoxine), i kūʻai ʻia ma lalo o ka inoa inoa ʻo Lucidril, ʻo ia kekahi o nā nootropics mua loa a i ʻike ʻia i kapa ʻia nā "akamai". ʻO ka nootropic i kaulana a mahalo ʻia nona i hōʻoiaʻiʻo iā ia iho no ma mua o ʻelima mau makahiki o ka hoʻohana ʻana a me ka hoʻokūkū koʻikoʻi hau lapaʻau.

Kuhi ʻia i ka 1959 e nā ʻepekema i ka French National Scientific Research Center ma ke ʻano he mālama no ka maʻi o Alzheimer, ʻaʻole i lawa nā kahe o ke koko i ka lolo, and a me ka hoʻokaʻawale ʻana i nā makahiki o ka makahiki, ua hoʻohana nui ʻia kēia lāʻau lapaʻau no ka mālama ʻana i nā pilikia pili i ka makahiki, e like me nā ʻano like ʻole. me ke Alzheimer a me ka panikala. Hoʻohana pū ia e nā poʻe olakino e hoʻoikaika i ka hoʻomanaʻo a me ka hana cognitive a hoʻomaikaʻi maikaʻi i nā olakino olakino holoʻokoʻa.

Ua hōʻike ʻia nā noiʻi i ka pauma centrophenoxine e lilo i mea hoʻomanaʻo hoʻomanaʻo hoʻomanaʻo a me ka anti-kahiko anti.

I loko oʻEulopa, ua kuhikuhi ʻia no ka mālama ʻana i nā hoʻomanaʻo o ka makahiki e pili ana i ka makahiki, akā ua loaʻa ia ma luna o ke counter a me kahi mea hoʻolako i ka papaʻaina i ka US a me Kanada, kahi mea e hoʻohana pinepine ʻia no kāna mau hoʻohui ʻoluʻolu.

He aha ia o Meclofenoxate (Centrophenoxine)?

Ua hoʻohana ʻia ʻo Centrophenoxine ma ke ʻano he meaʻaiʻai no kona mau pono e hoʻoikaika ai i ka hana.

ʻO Centrophenoxine ka hui ʻana o ʻelua mau huahana:

ʻO Dimethyl-aminoethanol (DMAE), he waiwai kūlohelohe i loaʻa i kekahi mau meaʻai (iʻa, ka wai kai a me nā mea liʻiliʻi i loko o ka lolo. He mea puna mai ia i ka choline a loaʻa nā hopena e hoʻoikaika ai ka lolo.

ʻO Parachlorphenoxyacetic acid (pCPA), kahi paʻi synthetic o nā lāʻau ulu o ka lāʻau i kapa ʻia ʻo "auxins".

ʻO DMAE ka mea hana nui i kēia lāʻau lapaʻau. ʻAʻole pololei ʻo DMAE i ka pale koko-lolo. Akā, i loko o ka centrophenoxine, hiki iā ia ke hele i ka hala o ka lolo-lolo a hoʻokomo maikaʻi i ka lolo

Hoʻokomo ʻia i ke kino, hoʻohele ʻia kahi hapa o ka centrophenoxine i ka DMAE a me ka pCPA i loko o ka ate. A laila hoʻohuli ʻia ka DMAE i ka choline, aʻo ka koena centrophenoxine e kū nei i ke kino holoʻokoʻa.

Nā pono Meclofenoxate (Centrophenoxine) i loaʻa

Hiki ke kōkua ʻo Centrophenoxine i ka hoʻoulu ʻana i ka maʻi maʻi.

Hiki ke kōkua ʻo Centrophenoxine i nā hōʻailona o ka dyskinesia tardive.

Hoʻonui ka Centrophenoxine i ka hoʻomanaʻo a me ka aʻo ʻana, hiki ke hoʻomaikaʻi i ka hoʻomanaʻo ʻana i nā mea maʻi dementia.

Ua hōʻike ʻia ʻo Centrophenoxine e hoʻomaikaʻi i ka hoʻokumu ʻana, mālama, a loaʻa hou i nā hoʻomanaʻo. E hoʻomaikaʻi ʻia ka hana hoʻomanaʻo ʻana inā loaʻa iā mākou nā kiʻekiʻe kiʻekiʻe o ka acetylcholine. Hōʻike i ka hoʻonui ʻana o Centrophenoxine i nā hana cholinergic i hoʻokahi, ʻo kekahi o nā mea i hana ʻia he choline, ma waena o nā phospholipids like ʻole.

Hoʻohui i nā Cognitive Function

Hiki ke hoʻohana ʻia ʻo Centrophenoxine e like me ka prodrug DMAE a ʻoiai he mea nui loa kēia, ʻoiai mea maikaʻi loa kēia molekue i ka hōʻemi ʻana i nā molekoleko ʻē aʻe i loko o ka lolo e hiki ai ke hōʻemi i ka hana hōʻemi ma nā hana cognitive. Me kēia mau molekala e hoʻokuʻu ʻia, hiki i ka poʻe ʻelemakule ke hoʻolōʻihi i ko lākou wā lohi a hoʻohuli i kekahi mau ʻaoʻao o ka wā kahiko.

ʻO Centrophenoxine ka anti-Aging a me Neuroprotective Properties

Ua hōʻike ʻia ʻo Centrophenoxine e hoʻonui i ke ola o nā kiʻi a hiki i 50%.

Hoʻonui ka Centrophenoxine i ka Mood a me ka Motivation, hiki iā ia ke kōkua i ka hōʻoluʻolu o ka hopohopo.

Ke hōʻike nei nā haʻawina holoholona i ka centrophenoxine he nui ka hopena anti-anxiety

Hoʻopilikena (Centrophenoxine) metabolism

Hoʻohana nui ʻia ʻo Centrophenoxine ma ka hoʻopuka a hoʻonui ʻana i nā hana o ka choline. ʻO Choline ka mea i hoʻomaka ai ka acetylcholine, kahi neurotransmitter koʻikoʻi a palena ʻole i pili pū me ka cognitive acuity, plasticity, a me ka hoʻomanaʻo. ʻAʻole maopopo ia pehea ka hoʻonui pinepine ʻana o ka centrophenoxine i nā pae o ka choline a me acetylcholine, akā ua manaʻo ʻia e hāʻule maoli paha i ka choline a i hoʻohuli ʻia i kahi phospholipid waena o ka wā i hoʻohana ʻia e hana i ka acetylcholine. Ka mea ʻole o ke ala, ʻo ia ka mea hiki ke cholinergic i mea e loaʻa ai ka centrophenoxine me kahi pototika nootropic ikaika.

I ka hoʻohui ʻana o ka hana acetylcholine, ʻike pū ʻia ka centrophenoxine i kahi ikaika neuro ikaika e hoʻoulu ai i ka hana o ka lolo ma o ka hoʻomaikaʻi ʻana i ke kūmole glucose a hoʻonui i ka piʻi o ka oxygen. Me ka hana ʻana, hana nui ka sentrophenoxine i ka hana o ka lolo i ka hana pono, no laila e hoʻomaikaʻi ai i ke kiko, ʻona, a me ke ʻano o nā manaʻo, e hoʻokuʻu aku ana i ka ʻohu ʻohu ʻohu. E like me ka nui o ka antiioxidant, ke kahili nei i nā mea hoʻopuka manuahi, e hoʻohemo i nā mea kinikini a komo i ka hoʻoponopono hou ʻana i nā puna i hoʻopau ʻia. ʻO ka mea hope loa, e hōʻole ana i ka ʻōpū o ka cognitive ma o ka hōʻemi ʻana a i ʻole ke hoʻopau ʻana i ka kūkulu ʻana o nā huahana mea ʻōpala metabolic i manaʻo ʻia he "pālule a waimaka."

ʻO nā hopena ʻaoʻao a me ka palekana Meclofenoxate (Centrophenoxine).

Hoʻomaopopo pinepine ʻia ʻo Centrophenoxine e palekana a me ka mea ʻole-mea iona. Ua hoʻohana ʻia no ia ma kahi o 50 mau makahiki me ka ʻole o nā ʻaoʻao koʻikoʻi nui i hōʻike ʻia.

Ua ʻōlelo ʻia he lāʻau hoʻomau like ʻole no ka poʻe olakino olakino a me ke senile e loaʻa ana i ka hoʻomanaʻo hoʻomanaʻo.

Eia nō naʻe, ua loaʻa kekahi mau mea hoʻohana i nā hopena ʻoluʻolu a me nā hopena liʻiliʻi, e komo pū ana i ka nausea, ka poʻo, ka pilikia o ka gastrointestinal, a me ka hiamoe ʻole.

ʻAʻole ʻōlelo ʻia ʻo Centrophenoxine no nā wahine hāpai ma muli o ka ʻike DMAE.

Hoʻopilikena (Centrophenoxine) papa ʻaʻa

Loaʻa ka Centrophenoxine ma luna o ke kahua i loko o nā kapoti i loaʻa ka 200-300 mg pākahi. ʻO nā hoʻokolohua haukapila i hoʻāʻo ai i ka hopena o nā centrophenoxine ma nā hana cognitive i hoʻohana i nā kaila o kēlā me kēia lā

1,200 mg i nā olakino ololi a me nā poho a hiki i ka 2,000 mg i nā maʻi maʻi dementia.

Hoʻoponopono

He ʻohi puna maikaʻi ʻo Centrophenoxine a hiki iā ʻoe ke ʻike i ka nui o ka puʻupuʻu nootropic - ʻo kekahi o nā mea maʻamau ka Noopept a me Racetams.

ʻO Centrophenoxine a me Aniracetam Stack

Eia kekahi laʻana o kahi pānaʻi centrophenoxine e loaʻa ai i ka aniracetam racetam kaulana e hoʻolako ai i ka hoʻomanaʻo ʻana, ke ʻano, ka ʻoluʻolu, a me ka hoʻohaʻahaʻa ʻana i ka hopohopo.

1-2x i kēlā me kēia lā

250 mg Centrophenoxine

750 mg Aniracetam

ʻO Centrophenoxine a me Noopept Stack

Eia kekahi laʻana o ka pānaehana centrophenoxine me Noopept, hiki i kēia mākeke ke hoʻomaikaʻi i ka hoʻomanaʻo a me ke aʻo ʻana, ʻoiai e hāʻawi ana i nā waiwai neuroprotective.

1-2x i kēlā me kēia lā

250 mg Centrophenoxine

20 mg Noopept

Reference:

• I ka hana o ka physicochemistry intracellular i loko o ka hōʻike genitative i ka wā o ka wā ʻelemakule a me ka hopena o ka centrophenoxine. He loiloi. Zs-Nagy I et al. ʻO Arch Gerontol Geriatr. (1989)
• ʻO ka lāʻau lapaʻau Cholinergic no ka dyskinesia tardive ant-sous-induced. Tammenmaa-Aho I, Asher R, Soares-Weiser K, Bergman H. Cochrane Pūnaewele Syst Rev. 2018 Mar 19
• ʻO ka hana Cytotoxic o nā mea hoʻomehana alkylating i mua o ka centrophenoxine a me nā huahana hydrolysis. Sladek NE. J Pharmacol Exp Ther. 1977 Dec
• Potentiation o ka hana antitumor o ka cyclophosphamide e ka centrophenoxine. Kanzawa F, Hoshi A, Tsuda S, Kuretani K. Gan. 1972 Aug
• Centrophenoxine: nā hopena i ka ulu ʻana o ka lolo mammalian. Nandy K et al. J Am Geriatr Soc. (1978)
• ʻO ka hopena ʻokoʻa o ka meclofenoxate ma ka nalowale o ka hoʻomanaʻo i ka pākeke. Marcer D et al. Ika waʻumea. (1977)
• Nootropics pauku centrophenoxine (meclofenoxate) pōmaikaʻi a me ka paʻa