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Ka Pahūpili Mahuhi Nui (97-07-5)

ʻO keʻano o ka Synephrine i nā lālā ulu o kaʻohana Rutaceae, he alkaloid sympatimous. Heʻekolu manawa o Synephrine ...... ..


Kūlana: I ka Production Production
Mokuna: 25kg / Drum
nona iho: 1370kg / ka mahina

Description

ʻO ka wikiōʻo Raw Synephrine (97-07-5)

Ka Pahūpili Mahuhi Nui (97-07-5)

ʻO ka hoʻouluʻanaʻo Synephrine he mea hana kūlohelohe ia iʻimiʻia e nā mea pāʻani a me ka poʻe e nānā ana e lilo i ka kaumaha no ka hopena o ka hanaʻana o ka kino. Eia nō naʻe, hiki i kēia pūpū ke hana like he mea antioxidant a me ka mea anti-inflammatory a hiki ke loaʻa i kekahi mau waiwai maikaʻi'ē aʻe.

ʻO kaʻohe nuiʻo ka Synephrine he amine.ʻO ka mea i loaʻa ma nā kiʻekiʻe i nā peels o nā kumulāʻau ulu, e like me kaʻalaniʻeleʻele a Seville orange (Citrus aurantium). Ua hoʻohanaʻia nā hua o nā hua aiʻole nā ​​peels o kēia mau mea kanu i nā lāʻau lapaʻau Pelekane maʻamau e mālama ai i nā pilikia o ka'ōpū a me nā maʻiʻaeʻa no nā haneli mau makahiki.

ʻO kaʻohe hanu'ohāhā (97-07-5) Hōʻike

Product Name ʻO ka pāpū nuiʻo Raw Synephrine
Hawaiian Name Kehena; Oxedrine; P-Synephrine; Parasympatol; ʻO Sympaethamine
Brand Name Yocon
Kōpana Drug Ua hala ka momona
Kāleka CAS 97-07-5
InChIKey YRCWQPVGYLYSOX-UHFFFAOYSA-N
hakakino F'Oula C9H13NO2
hakakino Wʻewalu 167.208 g / mole
Monoisotopic Mass 167.095 g / mole
Hoʻolaha Pʻo kaʻaila 162 a 164 ° C
ʻO Boiling Point 295.79 ° C (kūpono kūpono)
ʻO ka Halifa-Ola ʻAʻohe lā i loaʻa
kala like 'ole ʻO ka'ōmaʻomaʻo i ka paukūʻeleʻele
Solakino ʻAʻohe lā i loaʻa
Ska hoʻokele Tka mahana Pūmole
Apaukū ʻO ka hopena ka mea momona momona

ʻO kaʻohe hanu nui (97-07-5) Hōʻike

ʻO Synephrine, i kapaʻia he "p-synephrine," kahi hanaʻia ka alkaloid. ʻO ka māhele nui o nā agonists adrenergic he p-synephrine, a ua kākauʻia ma pharmacopoeia mai Northern Europe a me Kelemānia. Aia i loko o nā hua lāʻau lāʻau i'āponoʻia e like me ka neo-synephrine, kona analog i hoʻololiʻia. p-synephrine a me ka m-synephrine uaʻikeʻia no ko lākou mau hana lōʻihi lōʻihi e hoʻohālikelikeʻia i ka norepinephrine. Hiki ke hoʻohanaʻia i nā hōʻailona maʻamau o ka hānō maʻamau, ke kuhiakau, ka hāʻuleʻana, ka hoʻoulu, a me ka hypotension orthostatic; e hoʻonui i ka pili o ka pono; a ma nā hōʻailona o nā pilikiaʻeleʻele e like me ka maʻi momona, ka hua o ke ake, phlegm, a me nā ptosis.

I nā'āina'ē, uaʻimiʻia e ka poʻe 'elele a me ka poʻe e nānā ana e lilo ka kaumaha no ka hopena o ka ikaika o ke kino. Hoʻokomoʻia ka Synephrine no ka mālamaʻana i ka momona ma ka hoʻonuiʻiaʻana o ka lolaʻai a me ka momona waipona, a me ka mitigating i ke kaumaha o ke kino i hanaʻia e ka momona. Eia nō naʻe, hiki i kēia pūpū ke hana like he mea antioxidant a me ka mea anti-inflammatory a hiki ke loaʻa i kekahi mau waiwai maikaʻi'ē aʻe.

ʻO ka hoʻouluʻanaʻo Synephrine he amine biogenic. Loaʻaʻo ia ma nā kiʻekiʻe kiʻekiʻe i nā peels o nā kumulāʻau ulu, e like me kaʻalaniʻeleʻele a Seville orange (Citrus aurantium). Ua hoʻohanaʻia nā hua o nā hua aiʻole nā ​​peels o kēia mau mea kanu i nā lāʻau lapaʻau Pelekane maʻamau e mālama ai i nā pilikia o ka'ōpū a me nā maʻiʻaeʻa no nā haneli mau makahiki. I kēia manawa, hoʻohana nuiʻia ka p-synephrine i loko o nā mea lapaʻau, meaʻai, mea inu, a me nāʻoihana'ē aʻe.

ʻO kaʻeha hanu (97-07-5) Mechanism of Action

ʻO nā hopena cardiovascular o nā ligands e pili ana i ka hoʻopaʻaʻana o ka liʻiliʻi adrenergic. Ma keʻano laulā, i ka wā e paʻa ai nā liga i nā haipena-a-adrenergic, hanaʻia ka vasoconstriction, ai ka wā e paʻa ai i nā haipule'ēahana β1, ka contractilvascular contractility a me ka hopena o ka hopena o ka puʻuwai. Hōʻike nā haʻawina e hōʻike ana ka paina synephrine i nā'anakoki β3-adrenergic, e hoʻonui ai i ka mana o ke kino e wāwahi i nā momona. ʻO ka hoʻopaʻaʻana i nā'anakolu β3-adrenergicʻaʻole ia e hoʻonāuki i ka nui o ka naʻau a i ke kahe o ke koko. Eia hou, no ka mea, heʻuʻuku a liʻiliʻi paha ka synephrine i nā mea e loaʻa ai i ka α1, ka α2, ka β1, a me ka β2-adrenergic receptors aʻaʻole iʻikeʻia e hoʻoikaika i nā hopena adrenergic, nā hopena o ke koko, e like me ka hoʻonuiʻana i ka noʻonoʻo a me ke koko,ʻaʻole kaʻike i nā lāʻau i hoʻohanaʻia, e like me kekahi o nā mea'ē aʻe o ka phenylethylamine a me nā mea hua'ōlelo phenylpropanolamine. ʻO ka hopena o nā hopena liʻiliʻi liʻiliʻi i ka nui o nāʻokoʻa i ka hoʻopaʻaʻana o ka liʻiliʻi adrenergic a ma hope iho ka hiki ke hana i nā hopena o ka maʻi.

Hoʻonui ka Synephrine i ka hoʻohanaʻana o ke kino i nā'ōhūlū ma ka hoʻonuiʻana i ka ikehu ma keʻano o ka ATP.49-52 Hoʻonāukiuki i ka mālamaʻana o ka glucose i nā pūpū muscle, a me ka glycogenolysis, gluconeogenesis, glycolysis, a me ka hāpaiʻana i ka oxygen. Ke hoʻohālikelikeʻia nei ka hoʻokomoʻana o ka pahu calcium a me ka CAMP me nā mea'ālepa hoʻopili i nā hopena o kēiaʻano biochimique, e kuhikuhi ana i ke komoʻana o nāʻanoʻoihana.

Ma waho aʻe,ʻo ka hoʻohanaʻana i ka palapalapala Synephrine e kāohi i ka hoʻouluʻana o NF-kB. ʻO kēia kumu waiwai ka mea nui e hana ai i nā maʻi inflammatory e like me ka hānō. Uaʻikeʻia ka hoʻohanaʻana i ka Synephrine e pili i ka hana o ka hormone eotaxin-1 nui. ʻO kēia ka mea e kāohi i ka neʻeʻana o ka eosinophil i kahi i welaʻia.

ʻOiaiʻaʻole i hōʻoia maikaʻiʻia ma o nā hoʻokolohuaʻana, uaʻikeʻia ka hoʻohanaʻana i ka pauka Synephrine e kāohi ai i ka hana o ka acetylcholinesterase. Uaʻikeʻia kēia maʻamau i ka maʻi o Alzheimer.

Ke hoʻohanaʻiaʻana o ka paukū'āpala (97-07-5)

▪ Hoʻonui i ka hana hoʻoikaika

▪ Ka mālamaʻana i ka maʻi

▪ E kōkua i ka hana kaumaha

▪ Hoʻohaʻahaʻa i ke kaumaha ma mua o ka paeʻana

▪ Ke kāʻiliʻana i nā maʻi o ka maʻi fungal e like me ka'anikani, ka wāwae o ka meaʻoni, a me ka jock itch.

▪ Hoʻonui i nā Mood and Energy Levels

Hōʻoiaʻia kaʻeha Synephrine (97-07-5) Hana

ʻO nā kūlana kūikawā o ka palapona Maʻemaʻe ka 50-100mg i kēlā me kēia lā a me ka 30-40 mau minuke ma mua o ke kauʻana. Aʻo ka mea maikaʻi loa i ka kakahiaka a iʻole ka 15 - 30 mau minuke ma mua o ka hana. Pono e laweʻia kaʻehu waipona me ka wai ma mua o ka hana.

Nā Pōmaikaʻi o ka Uila Lapaʻau (97-07-5)

♦ Uaʻikeʻia kahi haʻawina (DB-RCT) o nā kānaka 12 e hoʻolālāʻia ka palahalaha synephrine i nā minuke 45 ma mua o ka hoʻonuiʻana i ka helu o nā hua'ōlelo hou a me ka pae kaulike i kauʻia i ka hanaʻana i nā'āpana i kūlike i kahi placebo.

♦ Nā noiʻi mua e hōʻike i ka inuʻana i ka papa mai nā lau o ka snakeroot a me ka hua o kaʻalaniʻeleʻele no nā makahiki 4 e hoʻemi ana i ke kiʻekiʻe o ke koko i nā kānaka me ka maʻi dia.

♦ʻO kahi hui o ka synephrine, caffeine, a me ka wort St. John e hiki ke kōkua i ka hoʻohaʻahaʻa kaumaha ke hoʻohanaʻia me kaʻai a me ka hoʻomehana haʻawina haʻahaʻa.

♦ Ua hōʻikeʻia kahi haʻawina (DB-RCT) o nā mea 10 i hāʻawiʻia i ka 50 mg o ka synephrine ua kāpili nā kumu i nā kalo'ōlelo 65 ma mua o kahi placebo i hāʻawiʻia i nā minuke 75 mua ma hope o ka laweʻana i ke kākoʻo.

♦ʻImiʻia e kaʻimiʻana i ka laweʻana i kaʻaʻalaʻalaʻalaʻelua mau lā ma mua o ka hikiʻana o ke kāpili e hoʻohaʻahaʻa iho i ka makaʻu.

♦ Hilani kaʻaila hinu, kahi i loko o ka synephrine e pili ana i nā mea hana'ē aʻe, ma kahi hoʻokahi o nā maʻi 60, hōʻeha maikaʻi i kaʻili o kaʻoki (fungal, body / skin, or groin) ma 2 a 3 wiki ma luna o 80% o nā mea komo.

♦ Mice me nā hōʻailona likeʻole o ke kaumaha, e like me nā pilikia o ka moe a me nā loli i nāʻanoʻai, e hanaʻino i ka paneʻana i nā hanana koʻikoʻi, e like me ka hoʻoikaikaʻia eʻauʻau, ma mua o nāʻiole ola. Ua hōʻike kekahi hoʻokahi i nā muse i hānai i ka paina synephrine i hiki keʻauʻau lōʻihi, e hōʻike ana i ka ike a me ka nui o keʻano

♦ Ua hōʻike kekahi o nā hoʻokolohua hoʻokolohua i ka palahine synephrine i ka hikiʻole i ka uluʻana o kekahi bacteria me E. coli, hiki ke hoʻoweliweli i ka meaʻai, a me Staphylococcus aureus, ka mea e hiki ai i nā maʻiʻeleʻele.

♦ʻO kahi haʻawina i hoʻohanaʻia me ka puaʻa puaʻa, hōʻikeʻo ka synephrine i hoʻohaʻahaʻa i nā spasms o ka mīkī maʻemaʻe i ka trachea, kahi hōʻailona pili i ka lolo. Ua hōʻemiʻia ka maʻi hānai i nā hōʻailona hānō i hanaʻia i ka hāʻawiʻiaʻana o nā mea hōʻike i nā mōʻaukala.

♦ I nāʻiole me kaʻehaʻeha, ua hoʻoemi ka synephrine i ka helu o nā pūnaewele inflammatory a me nā cytokine inflammatory TNF-alpha a me IL-6, i ka hoʻonuiʻana i ka anti-inflammatory IL-10.

NA HALO A E HOOLAHA:

E kūʻai ʻia ana kēia ʻano mea no ka noiʻi noiʻi wale nō. Wahi a ke kūʻai aku. ʻAʻole no ka loiloi kanaka, ʻaʻole lāʻau lapaʻau, manu hoʻāno, a i ʻole e kōkua ʻia nā mea hale.


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