Lactoferrin (146897-68-9)

Lactoferrin (146897-68-9) wikiō

Lactoferrin ka lehu Snāʻike

Product Name	Lactoferrin
Hawaiian Name	lactotransferrin (LTF)
Brand Name	N / A
Kōpana Drug	N / A
Kāleka CAS	146897-68-9
InChIKey	N / A
hakakino F'Oula	C141H224N46O29S3
hakakino Wʻewalu	87 kDa
Monoisotopic Mass	N / A
ʻO ka paila	N / A
Fkū hou Pʻo kaʻaila	N / A
ʻO ka Halifa-Ola	N / A
kala like 'ole	nonono
Solakino	H2O: 1 mg / mL
Ska hoʻokele Tka mahana	2-8 ° C
Apaukū	N / A

 

He aha Lactoferrin?

ʻO Lactoferrin (LF), ʻike ʻia ʻo ka lactotransferrin (LTF), he glycoprotein i hōʻikeʻike nui ʻia i nā ʻano mea huna pilikino e pili ana me ka waiū. Kūpono ka piha piha piha kōmua CRM e like me ka hoʻomaka ʻana no ka hoʻohana ʻana i nā calibrator a i ʻole nā ​​mana no nā ʻano hoʻokolohua ʻ applicationslelo a LC-MS / MS me ka hoʻāʻo ʻana i ka ʻenekini, ka hoʻāʻo ʻana o ka pēpē, ka papa meaʻai a i ʻole ka hoʻoponopono ʻia a me ka hoʻoweliweli diagnostic.

ʻO Colostrum, ka waiū mua i hana ʻia ma hope o ka hānau ʻana o kahi pēpē, aia nā kiʻekiʻe o ka lactoferrin, ʻehiku mau manawa o ka nui i loaʻa i loko o ka waiū i hana ʻia ma hope. Loaʻa hoʻi ka Lactoferrin i nā palaila i ka maka, ka ihu, ka pāheʻe ʻana o ka ʻōpū, ka ʻōpū, a me nā wahi ʻē aʻe. Hoʻohana ka poʻe i ka lactoferrin i mea lapaʻau.

Hoʻohana ʻia ʻo Lactoferrin no ka mālama ʻana i nā ʻōpū o ka ʻōpū a me nā ʻōpū o ka ʻōpū, ke kuʻuna, a me ka maʻi hepatitis C. Hoʻohana ʻia nō hoʻi ia e like me ka antioxidant a pale i nā maʻi o nā maʻi a me nā maʻi. ʻO nā hoʻohana ʻē aʻe e hoʻoulu ai i ka ʻōnaehana pale, pale aku i ka pōʻino o ka pehu e pili ana i ka wā kahiko, ka hāpai ʻana i nā huakaʻi maʻi o ke kino, pale ʻana i ke kanesa, a hoʻoponopono pū i ke ʻano o ke kino i ka hao.

Ke manaʻo nei kekahi poʻe noiʻi e pili ana ka lactoferrin i ka hopena i nā pilikia olakino e like me ka nele o ka hao a me ka maʻi kaumaha.

I ka mahiʻai kumuhana, hoʻohana ʻia ka lactoferrin e pepehi i nā pōʻino i ka wā o ka hōʻiliʻili ʻai.

ʻO Lactoferrin kahi ʻāpana o ka ʻōnaehana pale a he hana antimicrobial. Ma waho aʻe o nā hana nui o ka hoʻohui a me ka lawe ʻana i ka hao, aia pū kekahi me Lactoferrin nā hana a me nā ʻano o ka lāʻau antibacterial, antivirus, ke kūpaʻa ʻana i nā parasites, catalysis, ka pale ʻana i ka maʻi ʻaʻai a me ka hakakā ʻana me ka maʻi ʻaʻai, ka maʻi āpau a me ka pale radiation. Lawe kekahi poʻe i nā mea hoʻopihapiha lactoferrin e loaʻa ai nā pono antioxidant a me anti-inflammatory.

Loaʻa ia Lactoferrin

Nā hopena anti-inflammatory

ʻOiai ʻaʻole i hoʻokō ʻia ka hana pololei, ʻo ka lactoferrin ka mea i ʻike ʻia e ka anti-inflammatory i nā kānaka.

ʻO ka Lactoferrin i ke kahe amniotic he mea koʻikoʻi ia e hōʻemi ai i ka hoʻōla ʻana o ka fetal i nā wahine hāpai ma o ka hōʻemi ʻana i nā pae IL-6 a hoʻemi i ka maʻi a me ka hopena o ka ʻeha.

He mau mea kūpono e anti-inflammatory i ka wā e hoʻopili ai me ka ʻōnaehana pale i ka maʻi Epstein-Barr, hōʻemi i ka hoʻowalewale ʻana me ka lawe ʻana i ka hoʻōla ʻana o TLR2 a me TLR9 i ka DNA kino.

Nā kumuwaiwai Antibacterial

Kōkua ʻo Lactoferrin i ka hoʻōki o ka hana o nā huakini. ʻO ka hapa nui o ka huakaʻi e pono ai ka hana hao, a hiki ke lactoferrin ke pani i nā pōʻino mai ka lawe ʻana i ka hao i loko o ke kanaka.

Ma kahi o kēia, hiki iā ia ke pale i ka metabolism o nā mea make o ka bacteria, hoʻonāukiuki i ko lākou pā o cell, a i ʻole ke hui pū me nā lysozymes i ka waiū e pani ai i nā maʻi.

Nā ʻikepili i ka Hoʻoulu ʻia / Fetant

Pono nā pēpē i lactoferrin e hoʻomohala a hoʻololi i ka pūnao o ka ʻōpū. ʻO ia ke kuleana no ka hoʻokaʻawale ʻana i nā ʻāpana epithelial poʻomanaʻo liʻiliʻi, e hoʻopili ana i ka pākīpī liʻiliʻi liʻiliʻi, lōʻihi, a me ka haʻi o ka enzyme.

I nā keiki fetuses, ʻo lactoferrin e lawelawe nei i ka mea hoʻoponopono lāʻau ulu i nā manawa mua o ka ulu ʻana o ka iwi kanaka.

Hoʻokomo ʻo Lactoferrin i ka ulu ulu ʻana o ka cartilaginous i nā manawa like o ka hoʻomohala ʻana i ka wā liʻiliʻi ma o ka hoʻoulu ʻana i nā osteocytes immature a me osteoblasts.

I nā pūpū kanaka, hoʻoikaika ʻo Lactoferrin i ka hoʻopili ʻana o ka hao a me ke kūkulu ʻana i ka palena o ka lika, e ʻae ana i ka ulu ola a me ka hoʻomohala ʻana ma mua o ka hānau ʻana.

ʻO nā keʻena kiʻekiʻe o Lactoferrin i ka lōlopō e pale aku i ka maʻi a me nā hakahaka o nā membus fetal aʻo ka hoʻonui ʻana i ka maʻalahi o ka hana.

 

Pehea e hana ai ʻo Lactoferrin?

Kōkua ʻo Lactoferrin i ka hoʻoponopono ʻana i ka hoʻopale ʻana o ka hao i loko o ka pūpū a me ka hoʻopuka ʻana i ka hao i nā mea puna.

Me he mea lā nō ka pale ʻana i ka maʻi bakteria, mā ka pale ʻana i ka ulu ʻana o nā mea maʻi ma o ka hoʻihoʻi ʻana iā lākou o nā mea pono kūpono a i ʻole ka pepehi ʻana i nā mea make e ka luku ʻana i kā lākou mau paia. Loaʻa ka lactoferrin i loko o ka waiū makuahine e kōkua i ka pale ʻana i nā pēpē i hānai ʻia i nā maʻi maʻi o nā maʻi maʻi.

I ka hoʻomakaʻana i nā maʻi bakteria, ʻo ka lactoferrin he mea ikaika e kū'ē i nā maʻi i hoʻoiho ʻia e kekahi mau maʻi a me nā fungi.

A ʻo Lactoferrin kekahi e pili pū me ka hoʻoponopono ʻana i ka hana a ka iwi molowa (myelopoiesis), a hiki ke ʻike ʻia i ka ʻōnaehana pale (pale) i ka ʻōnaehana.

 

Nā hopena hopena Lactoferrin

Palekana ʻo Lactoferrin kaola i nā nui i hoʻopau ʻia i ka meaʻai. ʻO ka ʻai ʻana i ka nui o nā lactoferrin mai ka waiū o ka bipi e palekana paha a hiki i hoʻokahi makahiki. Hana ʻia ka lactoferrin kanaka mai ka laiki hana kūikawā e palekana a hiki i ka 14 mau lā. Hiki i ka Lactoferrin ke kumu i ka palahī. I nā koina kiʻekiʻe loa, ua hōʻike ʻia ka ʻele o ka ʻili, ka make ʻole o ka makemake, ka luhi, ka haʻalulu, a me ka paʻa paʻa.

 

Lactoferrin pauma hana a me ke noi

INFANT MILK MA A LACTOFERRIN

Ma nā keiki liʻiliʻi i hānau hou ʻia, nā waiū pēpē i hoʻonui ʻia me ka lactoferrin (me a ʻole ke probiotics) e hōʻemi ana i ka hōʻeha o ka septicemia lohi (bacterial a fungal) paha.

Ma ka hohonu hohonu ka hopena o nā hopena i hōʻike mai ua hoʻemi ʻia ka maʻi bovine lactoferrin ma mua o ka pale ʻana i ka pua. Hōʻike kēia i ka hiki i ka lactoferrin ke pale i nā maʻi kulekele mai ka ulu ʻana i ka maʻi ʻōnaehana.

Hiki i Bovine lactoferrin ke hoʻohaumia i ka punawai koko-lolo ma o nā ʻaluna kūikawā, a hoʻomaikaʻi i ka neuroprotection, neurodevelopment a me nā haʻawina i nā mammals.

 

Reference:

• Barrington K et al, Ka Lākana Lacuna: kahi ʻelua hoʻokō paʻa pālua no ka hoʻokolokolo hoʻokolohua o ka lactoferrin supplementation i loko o ka pēpē keiki pono loa, ʻo J Perinatol. 2016 Aug; 36 (8): 666-9.
• Lauterbach R et al., Lactoferrin - kahi glycoprotein o nā hiki ke hoʻōla maikaʻi, Dev Period Med. 2016 Apr-Jun; 20 (2): 118-25.
• Autofagy o Nbr1-hoʻoponopono ʻia ma Lactoferrin-hoʻohuihui osteoblastic ʻokoʻa. Zhang Y, Zhang ZN, Li N, Zhao LJ, Xue Y, Wu HJ, Hou JM. ʻO biochem Biotechnol Biochem. 2020 Mar
• Ka hopena o ka hopena o ka Bovine Lactoferrin Fortification ma ka Iron Metabolism o nā keiki Anemic. Chen K, Zhang G, Chen H, Cao Y, Dong X, Li H, Liu C. J Nutr Sci Vitaminol (Tokyo). 2020
• Lactoferrin: He Luna Kūʻai Kūʻē ma Neonatal Host Defence. Telang S et al. Nā mea hoʻonaʻauao. (2018)
• Role o Lactoferrin ma Neonates a me nā pēpē: He Hou. Manzoni P et al. Am J Perinatol. (2018)
• Ka hoʻohui hoʻohui lactoferrin no ka pale ʻana i ka sepsis a me ka necrotizing enterocolitis i nā pēpē preterm. Pammi M et al. Kaʻikepili Pūnaewele Cochrane (2017)
• He aha nā mea hoʻohui Lactoferrin i pōmaikaʻi ai i nā pākeke a me nā pēpē?

 

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