Paheʻe Pterostilbene pauku (537-42-8)

December 28, 2018
SKU: 537-42-8
5.00 i waho o 5 ma muli o 1 Customer pane lākiō

ʻO ka paukū Pterostilbene he antioxidant e waiho muaʻia ana i nā mīkini, nā māla waina a me nā ululāʻauʻulaʻula. Pterostilbene .......


Kūlana: I ka Production Production
Mokuna: 25kg / Drum
nona iho: 1180kg / ka mahina

ʻO ka'ōmole uila Pterostilbene (537-42-8)

Paheʻe Pterostilbene pauku (537-42-8)

ʻO ka Pterostilbene ka pauka he stilbenoid i loaʻa i pili i ka resveratrol, me nā hana antioxidant, anti-inflammatory, pro-apoptotic, antineoplastic and cytoprotective. Ma luna o ka hoʻolālāʻana, e hana ana ka hana'opiha hanaʻoleʻo Raw Pterostilbene e ka scavenging reagene oxygen (ROS), a laila palekana i ka ikaika kaulike a me ka poino pūkole i hoʻokomoʻia e ROS. Hiki paha ia ia ke hoʻololi i ka huahana hoʻokuʻu o 2 (Nrf2) pili nui erythroid 2 me ka hoʻonui i ka manaʻo o nā enzymes antioxidants, e like me superoxide dismutase (SOD). Ma waho o kēiaʻano, hiki i kaʻaila Raw Pterostilbene hiki ke hoʻokuʻu i ka wela ma ka hoʻohaʻahaʻaʻana i ka'ōlelo o nā mea hoʻolaha inflammatory, e like me interleukin (IL) 1beta, alpha alpha-alpha alpha (TNF-a), nitric oxide synthase (iNOS) inducible, cyclooxygenases (COX) , a me ka puukui bila kappa B (NF-kB). Hoʻopilikia a hōʻole paha ia i ka hoʻouluʻana o nā alaloa hōʻailona e pili ana i ka carcinogenesis, a hoʻonui i ka hōʻikeʻana i nāʻano genes suppressor geno ma ka ho'ēmiʻana i ka'ōlelo o kekahi mau genes ulu hānai. Hoʻokomo pono ia i ka apoptosis ma nā pūpū tumo.

Paheʻe Pterostilbene pauku (537-42-8) Snāʻike

Product Name ʻO ka pākī Pterostilbene
Hawaiian Name Pālaʻi Pterostilbene;

4-(3,5-Dimethoxystyryl)phenol; (E)-4-(3,5-dimethoxystyryl)phenol; 3′,5′-Dimethoxy-4-stilbenol

Brand Name ʻAʻoheʻikepili no ka loaʻa
Kōpana Drug ʻAʻoheʻikepili no ka loaʻa
Kāleka CAS 537-42-8
InChIKey VLEUZFDZJKSGMX-ONEGZZNKSA-N
hakakino F'Oula C16H16O3
hakakino Wʻewalu 256.301 g / mole
Monoisotopic Mass 256.11 g / mole
ʻIke kūpono 256.11 g / mole
SMILES CC1=C(OC2=NC3=C(CCCC3)C(=C12)NC(=O)CN4CCCC4=O)C
ʻO ka Halifa-Ola ʻAʻoheʻikepili no ka loaʻa
kala like 'ole ʻO ka pauma
Solakino ʻAʻoheʻikepili no ka loaʻa
Ska hoʻokele Tka mahana E kūʻai i ke anahana o ke keʻena
Apaukū ʻO ka stilbenoid i loaʻa i keʻano i pili i ka resveratrol

ʻO ka Pterostilbene pauka (537-42-8) Hōʻike

ʻO Pterostilbene he mole methylated stilbene me ka hoʻohālikelike like me resveratrol,ʻo ka mea hoʻokahi wale nō keʻano o nā mea hanaʻelua ma ka mole mole pterostilbene e pani i nā hui hydroxy i ka mole o ka resveratrol. ʻOiai ka likeʻana o ka hapa nui o nā hana a lāuaʻelua, uaʻike nuiʻia ka pterostilbene ma muli o kaʻaiʻana o ka waha a hiki paha ke lilo i ka meaʻoi aku o ka manaolana a me ka mole'ālika.

Hoʻokahi wale nō papahana i loiloi i ka pterostilbene pauka i loko o nā kānaka. Ua loaʻa iā ia kahi hoʻonui i ka LDL-cholesterol a me ka piʻi i nā kiʻekiʻe o ka HDL i nā kānaka me nā kiʻekiʻe o ka cholesterol kiʻekiʻe nāna i lawe i ka 100 a iʻole ka 250 mg i kēlā lā. ʻAʻole maopopo i ka liʻiliʻi iho ka hopena haʻahaʻa i ka emiʻana o ke kahe o ke koko, akā, ua paʻakikī ka emiʻana o ka hui i lawe i ka nui.

ʻO ka paukū Pterostilbene (537-42-8) Mechanism of Action

Ke kaua neiʻo Pterostilbene i ka hoʻonāukiuki palekana ma o ka hoʻopiʻiʻana i nā enzymes antioxidant. Hoʻonuiʻia ka superoxide i ka 1 (SOD1) a me ka peroxiredoxin-4 (PRDX4), e hoʻopaʻa ai i nāʻano oxygen. Uaʻike nā mea noiʻi i kēia hopena ma nā pūnaewele maka o kānaka, e manaʻo ana e pale i ka pterostilbene mai ka pōʻino oxidative. Ma waho aʻe, hana pūʻo Pterostilbene i kahi alana hōʻailona SIRT1 e pale ana i ka pōʻino pūnaewele. Hiki i kēia ala ke hoʻonui i ka hōʻike o ka p53, he kinipona e mālama ana i ka DNA a kāohi i nā hoʻololi e hiki ke alakaʻi i ka maʻi kanesa.

Hiki iā SIRT1 ke pale aku i kekahi o ka hōʻino a me ka poino e mālamaʻia ana i ko kākou wāʻelemakule. Eia naʻe,ʻaʻole ka pterostilbene he pilikino kilokilo i kaʻelemakule.

Ua hōʻikeʻia nāʻano he nui e ho'ēmi ana ka pterostilbene i ka hoʻolālā i hoʻoholoʻia e ka helu-necrosis-alpha (TNF-alpha). Hoʻonāukiuki ka hopena i ka lī; hiki i ka pterostilbene ke pale i ka TNF-alpha a me interleukin-1b (IL-1b) ma ka hoʻonāʻana i nāʻano oxygen reactive.

Hoʻomaʻa pahaʻo Pterostilbene i ka pilikia ma loko o kahi māhele pūnaewele i kapaʻia ka retopulum endoplasmic, aiʻole ER paha. Ma kahi o nā haʻawina, i ka wā iʻikeʻia nā pūnaewele mai ka uhiʻana o nā moku koko i ka pterostilbene,ʻaʻole i pane ko lākou ER i nā hōʻailona inflammatory,ʻaʻole lākou i wela.

Loaʻa i ka Pterostilbene kekahi mauʻano hana kū'ē i ka hanu. Hiki ke pale i nā pūnaewele olakino a hoʻololi pono i nā pūnaewele kūpono. Ma nā pūnaewele kani (lolo a me ka maʻi āpau), ua emi iho ka pterostilbene i ka Bcl-2 a hoʻonui iā Bax; kēia mau hoʻololi e hoʻololi i nā pūnaewele "hoʻokomo" a me ka mea e make ai nā pūnaewele glioma.

Keʻike neiʻo Pterostilbene e hoʻoholo i nā hippocampus i ka lolo. Ma laila, hoʻonui i ka helu neurotrophia (BDNF), a me ka protein kinases (activated protein kinases) (MAPK), a me ka pūnaewele pane e paʻa ana i ka protein (CREB). ʻO kēia mau māmāʻekolu ke kōkua i nā mea kōkua e ulu, hoʻonui, a pane i ko lākou mau wahi. Nā SNide antidepressants e hoʻokau pinepine i kēia mau ala. I loko nō hoʻi o ka hippocampus, piʻi ka pterostilbene i kahi protein i kapaʻiaʻo Nrf2, a laila hoʻonui i ka hōʻike o nā protein antioxidant.

ʻO nā monoamine oxidases, MAO, he mau enzymes ia e uhaʻi i nā neurotransmitters i ka lolo. ʻO kekahi o kēia mau enzymes, MAO-B, hoʻohemoʻana i ka dopamine; ʻo ka hopena,ʻo nā lāʻau lapaʻau i loaʻa ka MAO-B i ka dopamine i loko o ka lolo. Wahi a kekahiʻike hou i kēia manawa, hana ka pterostilbene i ka hana MAO-B a, no laila, hoʻonuiʻia ka dopamine.

Hiki i ka Pterostilbene pauka ke pale i ka maʻi o Alzheimer ma o ka paleʻana i ka lolo mai ka beta-amyloid (Aβ). ʻAʻoleʻikeʻia ke ala pololei, akā,ʻikeʻia he PI3K a me Akt,ʻelua mau pilikino e kākoʻo ana i ka hoʻomanaʻo, ke aʻoʻana, a me ka uluʻana o ka ulu.

hoʻohana ʻO ka paukū Pterostilbene (537-42-8)

  • Alzheimer ka maʻi
  • ʻO ke atherosclerosis
  • Diabetes
  • Ke kaheʻie kiʻekiʻe
  • High naʻokoko
  • Ke kūʻana o ka insulin

Hōʻoiaʻia ka pauhana Pterostilbene (537-42-8) Hana

I loko o nā kānaka, hiki ke mālamaʻia ka lōʻihi o ka piʻiʻana i ka 250 mg i kēlā lā i kēia lā. Ua hōʻikeʻia ka nui o nāʻokoʻa like e like me kēia e ho'ēmi i ke koko a hoʻonui i kekahi kaumaha o ke kaumaha. Ua hoʻonui nuiʻia ka LDL cholesterol me ka maikaʻi, akā ua hoʻopihapihaʻia kēia hopena me ka hoʻohuiʻana i nā hua waina.

I loko o nā holoholona, ​​ua nui nā hopena o ka hopena o ka pahu. Ma waena o 1 a me 2 mg i kēlā me kēia kg o ke kaumaha o ke kino i kēlā lā i kēia lā, hoʻemiʻia ka puʻuwai i kaʻiole. Ma ka hoʻohanaʻana i ka heluʻana o ka helu likeʻana i waena o nāʻiole a me nā kānaka, ka laina hoʻomaka (i loko o ka mg) no ke kanaka ke kaumaha i ka kg i māheleʻia e 12.3. E hana ana i:

4.6 mg / lā no kahi kanaka 125 lb

5.5 mg / lā no kahi kanaka 150 lb

6.5 mg / lā no kahi kanaka 175 lb

7.3 mg / lā no kahi kanaka 200 lb

Ināʻoe e lawe ana i ka pterostilbene pauma no kona mau pono kīnā, makemake pahaʻoe e hoʻomaka me kahi maʻi liʻiliʻi loa. Eia naʻe, uaʻikeʻia nā hopena haʻahaʻa haʻahaʻa i nā maunu a hiki i kēia manawa, a hiki i nā kānaka ke hauʻoli maikaʻi loa i nā pōmaikaʻi i ka nui o nā mea.

Nā pōmaikaʻi o ka paukū Pterostilbene (537-42-8)

ʻO ka paukū Pterostilbene he antioxidant e waiho muaʻia ana,ʻo ia hoʻi he chemopreventive, antiinflammatory, antidiabetic, antidyslipidemic, antiatherosclerotic a me nā neuroprotective hopena. Ma waho aʻe, he mau pōmaikaʻi kekahi ma lalo:

  • Kōkua i ka hakakāʻana me ke kanulau
  • Hoʻonui i ka cognition a kāohi i ka make o ka maʻi ma ka lolo
  • Ho'ēmi i ka Suga Koko
  • E ho'ēmi i ka hoʻonaeho
  • Ke pale i ka Makani
  • Mei Paʻi i ka Lā
  • Hiki iāʻoe ke kākoʻo i ka Lemi Luku
  • Mālama i nā Hiʻona
  • Hiki iā Mei Lifespan
  • Ho'ēmi i ke kaumaha o ke koko

NA HALO A E HOOLAHA:

E kūʻai ʻia ana kēia ʻano mea no ka noiʻi noiʻi wale nō. Wahi a ke kūʻai aku. ʻAʻole no ka loiloi kanaka, ʻaʻole lāʻau lapaʻau, manu hoʻāno, a i ʻole e kōkua ʻia nā mea hale.