Dihydromyricetin (DHM) (27200-12-0)

March 9, 2020

ʻO Dihydromyricetin (a i ʻole DHM) ka mea lawe mai i ka lāʻau Laisin Raisin ka mea i hoʻohana ʻia no nā kenekulia he anti-alkohol …….


Kūlana: I ka Production Production
Hoʻonohonohoʻia a hoʻoponoponoʻia
nona iho: 1277kg / ka mahina

Nā wikiō Dihydromyricetin (DHM) (27200-12-0)

Hoʻonohonoho ʻia Snāʻike

Product Name Nāʻina pahuhopu (DHM)
Hawaiian Name Ampelopsin
Ampeloptin
(+) - Dihydromyricetin
Brand Name N / A
Kōpana Drug phytochemical; mau ʻōlelo kuhikuhi mai nā lāʻau lapaʻau China (TCM); manu hoʻohuihui standardized; product natural; Inhibitors; Flavanones; chemical reagent; pharmaceutical intermediate
Kāleka CAS 27200-12-0
InChIKey KJXSIXMJHKAJOD-LSDHHAIUSA-N
hakakino F'Oula C15H12O8
hakakino Wʻewalu 320.25 g / mole
Monoisotopic Mass 320.053217 g / mole
ʻO ka paila 780.7 ± 60.0 ° C (Manaʻo ʻia)
Fkū hou Pʻo kaʻaila N / A
ʻO ka Halifa-Ola N / A
kala like 'ole keʻokeʻo e kaomi
Solakino DMSO: ≥5mg / mL (ʻaina)
Ska hoʻokele Tka mahana <+ 8 ° C
Apaukū 1. Kuhi ʻia i loko o nā hana ʻai, dihydromyricetin powder i hoʻohana ʻia ʻo ia no nā mea maka ʻā;
2. Ke hoʻopili ʻia i nā huahana olakino, ʻaʻa dihydromyricetin i hoʻohana ʻia he mau mea pono e hoʻoikaika ai i ke ʻano kino;
3. Ke hoʻokomo ʻia i loko o ka lāʻau laila, dihydromyricetin extract powder i hoʻohana ʻia i ka capsules a i ʻole nā ​​peni e mālama ai i ka maʻi o ka hanu a pale aku i ka ate.

ʻO ka mōʻaukala Dihydromyricetin

ʻO Dihydromyricetin (a i ʻole DHM) kahi mea lawe mai ka Japanese Raisin Tree i hoʻohana ʻia i mau makahiki he mau lāʻau a me ke kūpaʻa anti-alkohol a me ka lāʻau hangover i kūlohelo ʻia i ka lāʻau kūloko a me ka Haʻomaʻo. Ua hōʻike aku nā noiʻi hou nei e hiki i ka DHM ke hoʻohaʻahaʻa i kou kiʻekiʻe ʻokoʻa o ka wai koko a pale i kāu puʻu mai nā meaʻino a me nā maʻi.

ʻO DHM ka flavonoid i ka huki loa mai ka Vine Tea akā hiki ke kiʻi ʻia mai ke ʻano o ka lāʻau Holvenia Dulcis. A ʻo ka mea nui loa, ua lō loa ka moʻolelo o Dihydromyricetin no ka mālama ʻana i ka ʻeha a me nā hangovers.

He aha ka mea ʻo Dihydromyricetin?

ʻO Dihydromyricetin, ʻo ia hoʻi ʻo Ampelopsin, he flavanonol, he ʻano flavonoid. Ua loaʻa i loko o nā ʻano nui o Ampelopsis japonica, megalophylla, a me grossedentata; Cercidiphyllum japonicum; Hovenia dulcis; Rhododendron cinnabarinum; kekahi mau huaʻāina Pinus; a me kekahi koʻo Cedrus, a me Salix sachalinensis.

ʻO ka hoʻoneʻe palaoa a Dihydromyricetin, ʻo ka mea hana nui ka flavonoids. Me nā hana o ka scavenging manuahi manuahi, antioxidants, antithrombotic, Tumor, anti-inflammatory a me nā hopena ʻē aʻe; ʻO ka Dihydromyricetin kahi mea hoʻohui kūikawā flavonoid kūikawā. Ma waho aʻe o nā hiʻohiʻona laulā o nā flavonoids, hiki nō iā ia ke hōʻoluʻolu i ka wai ʻawaʻawa, mālama i ka wai ʻawaʻawa, ka momona o ka momona, a me ka hoʻokaʻawale i nā puʻuwai. Hoʻopilikia a hoʻemi i ka hōʻeha o ka kanesa o ka ate. He huahana maikaʻi ia no ka paleʻana i ke ate a me ka hangover.

Hoʻonohonoho ʻia maika

HE ANO-HANGOVER KEIKI KUPUNU

ʻO ka pōmaikaʻi nui ʻo DHM ka pale ʻana a me ka hōʻemi o nā hangovers, i mea e pale ai i kou mauʻa a me kou lolo. Loaʻa kēia i ka hoʻonui ʻia o ka wai dehydrogenase (ADH) a me ka acetaldehyde dehydrogenase (ALDH), ʻo ia nā kuleana nui e pili pono ana i ka uhaʻi i ka waiʻona a me ka acetaldehyde i loko o ke kino.

ʻO ka Acetaldehyde ka mea hanohano he pakano mea kino a kekahi o nā kumu nui o nā hangovers. Ke hoʻonuiʻia kēia mau enzyme, hiki ke hoʻopau ʻokoʻa i ka wai a me ka acetaldehyde ma mua o ka maʻamau.

HE MELE HEILI

He nui nā waiwai olakino o DHM e hāʻawi nei iā lākou iho i ka hoʻolaha ʻana i ke olakino kognitive. Hoʻokumu kēia no ka mea e hoʻonani ʻo DHM i ka heme-oxygenase-1 (HO-1), kahi huina e hoʻokaʻawale i ka hōʻeha o ka heme a hoʻopaʻa i nā waiwai olakino olakino. Hiki pū i ka dihydromyricetin ke olakino i ka olakino.

Loaʻa nā pono o kahi dihydromyricetin

1) Hiki i Dihydromyricetin ke hoʻomaʻemaʻe i ke kahe manuahi i loko o ke kino a me ka antiioxidation

2) Hiki i ka Dihydromyricetin ke hana i ka hana Antibiotic

3) Hiki i ka Dihydromyricetin ke pale i ka Liver: Ua loaʻa ka momonay i ka hapydromyricetin i ka piʻi o ALT a me AST i loko o ke koko Serum. Hiki iā ia ke hoʻemi i ka bilirubin piha i loko o ka serum koko. No laila aia ka hana ikaika e hoʻohaʻahaʻa i ka aminotransferase a me ka jaundice.

4) Hiki i ka dihydromyricetin ke hōʻemi i nā pae o ke kō a me ke momona koko: Dihydromyricetin hiki ke hōʻemi i nā nui o ka momona o ke koko ma nā kiʻo. Hiki iā ia ke hōʻemi i nā pōʻino o nā ʻili o nā ate e hoʻonā e nā kiʻekiʻe o ka momona momona a hoʻomaikaʻi i ka hiki ke antioxidation. I ka manawa like, hiki iā ia ke hoʻohaʻahaʻa i nā pae o ke kō koko kiʻekiʻe.

5) Dihydromyricetin hiki iā Anti-inflammatory

6) Dihydromyricetin hiki ke Anti-tumor: Dihydromyricetin extract powder ka mea maikaʻi e pale aku i ka hoʻopiʻi ʻana o nā pūpū o kekahi mau ʻōiwi.

Nā hopena hopena o Dihydromyricetin.

Ma ke ʻano he liʻiliʻi wale nō nā haʻawina a hiki i kēia manawa ke nānā nei i ka ʻaoʻao hopena o DHMs a hiki i kēia manawa ʻaʻohe kuhihewa i hōʻike ʻia.

E hōʻike i kahi huli wikiwiki ma Amazon. Ke nānā nei iā lākou, aia kekahi mau lono o ka hōʻeha o ka ʻōpū, ke ʻuwā, a me nā maʻi hū. Eia naʻe, ʻaʻohe nui o nā mea kūʻai aku e hōʻike ana i kēia mau hopena.

Hoʻohana a hoʻohana ʻo Dihydromyricetin

Hoʻohana hoʻohana:

  1. Hoʻopilikia ka dihydromyricetin i mea e pale ai i ka ate;
  2. Hoʻopilikia ka dihydromyricetin i mea e hoʻoponopono ai i ka momona koko koko;
  3. ʻO ka pulapika ʻo Dihydromyricetin ka hopena o ka hoʻoikaika kino ʻana i ke kino;
  4. ʻO ka pulupulu Dihydromyricetin me ka hana o nā antioxidant a me nā anti-cancer;
  5. Hoʻopilikia ka dihydromyricetin i hoʻohana ʻia no ka antibiosis, mālama i ka umukū, nā ʻeha a me ka hoʻopau ʻana i ka ʻā o ka uahi.
  6. ʻO ka dihydromyricetin ke kākoʻo i ka hoʻolālā hoʻomohala ʻana i ka hoʻomākaukau ʻana i nā huahana mālama ʻili kino a i ʻole mau lāʻau no ka pale ʻana a me ka mālama ʻana i nā hōʻeha ʻili optical.

noi

  1. Hoʻohana ʻia i loko o ka ʻoihana hana, dihydromyricetin powder i hoʻohana ʻia ʻo ia no nā huahana maka;
  2. Hoʻopili ʻia i loko o ka huahana olakino, pauma dihydromyricetin i hoʻohana ʻia he mau mea pono e hoʻoikaika i ka pale ʻana i ke kino;
  3. Hoʻohana ʻia i loko o ka lāʻau laila, dihydromyricetin extract powder i hoʻohana ʻia i ka capsules a i ʻole nā ​​pills e mālama ai i ka maʻi o ka hanu a pale aku i ka ate.

Hoʻonohonoho ʻia noiʻi in Anti-maʻi maʻi

I ka ʻoiaʻiʻo, aia kekahi mau noiʻi makaʻama e hōʻike ana i ke hiki i ke dihydromyricetin e hiki ke kōkua me ke ʻano kīnā wai ʻole ʻia ka inoa ʻo Hepatocellular carcinoma (HCC). ʻO ka HCC kahi kūlana e hōʻike ana i kekahi o nā mea kiʻekiʻe loa o ka morbidity a me ka make ma ka honua a puni, a ke hāʻawi nei i ka subtype nui o ka maʻi palupalu mua. Ke hōʻike nei ʻo DHM i ka pale palekana ma ka puhā (he hepatprotective) hōʻike ʻia nā hopena i hōʻike nui ʻia ka hoʻomaʻamaʻa ʻana i nā cell cell a me ka apoptosis i hoʻokomo ʻia i nā laina kelepaʻi HCC, hōʻike ana i ko DHM ka manaʻo hoʻohiki no ka mālama ʻana i ka HCC.

Reference:

Hoʻopāla ʻia ʻo Dihydromyricetin i ka cardiotoxicity-hana o ka Doxorubicin e ka pale ʻana i ka inflammasome NLRP3 ma kahi o SIRT1. Sun Z, Lu W, Lin N, Lin H, Zhang J, Ni T, Meng L, Zhang C, Guo H. Biochem Pharmacol. 2020 Pepelu 26: 113888. doi: 10.1016 / j.bcp.2020.113888. [Epub ma mua o ka paʻi]

ʻO nā Metabolomics o ka hopena palekana o ka Ampelopsis grossedentata a me kāna kumu ʻoiʻi nui Hoʻopuu Hoʻopau ma nā maʻi o ka High-Fat Diet Hamster. Fan L, Qu X, Yi T, Peng Y, Jiang M, Miao J, Xiao P. Evid Based complement Alternat Med. 2020 Jan 28; 2020: 3472578. doi: 10.1155 / 2020/3472578. eoli 2020.

Ka hoʻoponopono o ke kau ʻana i nā ala ala e Ampelopsin (Dihydromyricetin) i nā maʻi kanesa: ka ʻimi ʻana i nā alahele nui a me nā huakaʻi hele ʻole. Fayyaz S, Qureshi MZ, Alhewairini SS, Avnioglu S, Attar R, Sabitaliyevich UY, Buha A, Salahuddin H, Adylova A, Tahir F, Pawlak-Adamska E. Cell Mol Biol (Noisy-le-grand). 2019 Sep 30; 65 (7): 15-20.

Hana ʻia ʻo Golgi a hoʻopili ʻana i ka protein 65 ka hoʻohaʻahaʻa ʻana i pono no ka hopena anti-cancer o ka dihydromyricetin ma nā ʻōnaehana maʻi ovarian. Wang F, Chen X, Yuan D, Yi Y, Luo Y.

ʻO Kekahi Hoʻokahi. 2019 Nov 26; 14 (11): e0225450. doi: 10.1371 / journal.pone.0225450. eCollection 2019.

NA HALO A E HOOLAHA:

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