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ʻO ka uila Flibanserin (167933-07-5)

ʻO ka Raw Flibanserin ka pauka he lāʻau lāʻau lapaʻau i hoʻomaopopoʻia no ka hoʻomaʻemaʻeʻana i nā wāhine premenopausal me ka loaʻaʻana, ka maʻamau maʻamau maʻamau ....


Kūlana: I ka Production Production
Mokuna: 25kg / Drum
nona iho: 1489kg / ka mahina

Description

ʻO ka wikiō uila Flibanserin (167933-07-5) wikiō

ʻO ka uila Flibanserin (167933-07-5)

ʻO ka Raw Flibanserin kaola, i kūʻaiʻia ma lalo o ka inoaʻo Addyi, he mea hana maʻamau a me ke antagonist mulipuna e hoʻohanaʻia ana no ka hoʻomaʻamaʻaʻana i nā wāhine pre-menopausal me ka maʻi hōʻeuʻeu o ka wahine (HSDD). Hoʻonui ka lāʻau i ka helu o nā hana pilina pili i kēlā me kēia mahina ma kahi o kahi hapalua o kahibo mai kahi kahi hoʻomaka e pili ana iʻelua aʻekolu. Ma ka manawa like, He kuleana kona e like me keʻano o ka agonist serotonergic, he diagonergic antagonist a me kahi antidepressant ..

Kōwīwī Raw Flibanserin (167933-07-5) Snāʻike

Product Name ʻO ka uila Flibanserin
Hawaiian Name 1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one
Brand Name Pākuʻi
Kōpana Drug ʻO ka agonist serotonin multifunctional a me ke antagonist
Kāleka CAS 167933-07-5
InChIKey PPRRDFIXUUSXRA-UHFFFAOYSA-N
hakakino F'Oula C20H21F3N4O
hakakino Wʻewalu 390.41 g / mole
Monoisotopic Mass 390.167 g / mole
Hoʻolaha Pʻo kaʻaila 225 ° C
ʻO Boiling Point N / A
ʻO ka Halifa-Ola ~ 11 hora
kala like 'ole ʻO ka White ka beige
Solakino DMSO: hoʻopū'āluaENDNUMXmg / mL, maopopo
Ska hoʻokele Tka mahana 2-8 ° C
ʻO ka uila Flibanserin Apaukū Ua hoʻolālāʻia no ka mālamaʻana i ka hōʻehaʻana o ka wahine ma ka wahine

ʻO ka uila Flibanserin pauka (167933-07-5) Hōʻike

ʻO Flibanserin kalo ka lāʻau mua loa i'āponoʻia no ka maʻi hōʻeuʻeu o ka wahine (HSDD) i nā wāhine premenopausal e ka FDA iʻAukake 2015. Ua hana muaʻiaʻo ia e like me ka lāʻau antidepressant e Boehringer Ingelheim, akā hōʻikeʻia ka nele o ka pono ma nā ho'āʻoʻana a ua ulu houʻiaʻo ia e like me ka maʻi maʻamau i ka maʻi maʻamau e Sprout Pharmaceuticals. Hanaʻia ka'ōnaehana o Flibanserin i kona hilinaʻi kiʻekiʻe no 5-HTA1 a me nā nūnū 5-HTA2, e hōʻike ana i ka hana agonist ma 5-HTA1 a me ka mea antagonist ma 5-HTA2, ka mea i hoʻohaʻahaʻa i ke serotonin ma ka lolo a me ka hopena i ka hoʻonuiʻana i nā norepinephrine a me nā neurotransmitamine dopamine.

ʻO Flibanserin pauka (167933-07-5) Mechanism of Action

Hanaʻia ka'ōnaehana o Flibanserin i kona hilinaʻi kiʻekiʻe no 5-HTA1 a me nā nūnū 5-HTA2, e hōʻike ana i ka hana agonist ma 5-HTA1 a me ka mea antagonist ma 5-HTA2, ka mea i hoʻohaʻahaʻa i ke serotonin ma ka lolo a me ka hopena i ka hoʻonuiʻana i nā norepinephrine a me nā neurotransmitamine dopamine. He kūlana kiʻekiʻe ko Flibansetrin no nā mea lohe i ka serotonin ma ka lolo: hanaʻo ia ma keʻano he agonist ma 5-HT1A a he mea hōʻailona ma 5-HT2A. I loko o vivo, flibanserin nakinaki i nā mea loaʻaʻo 5-HT1A me 5-HT2A. Eia nō naʻe, ma lalo o nā kiʻekiʻe kiʻekiʻe o ka lolouila 5-HT (ʻo ia hoʻi, ma lalo o ka pilikia), hiki i ka flibanserin ke komo i nā'onike 5-HT2A iʻoi aku ka nui aʻe ma mua o ka mau 5-HT (1A) pane. Hiki paha iā ia ke hāwanawana i nā leka uila D4 (dopamine) a me 5-HT2B a me 5-HTB2C. Hiki i kāna mau hana ma nā nee o ka neurotransmitter ke kōkua i ka ho'ēmi o ke kiʻekiʻe o ka serotonin a hoʻonui i ka dopamine a me nā norepinephrine, aʻo ia mau mea a pau e pāʻani i ka hana uku. Ua kūʻaiʻiaʻo Flibanserin ma lalo o ka inoaʻo Addyi a hōʻikeʻia no ka mālamaʻana i nā wāhine premenopausal me ka loaʻaʻana o ka maʻi maʻamau o ka wahine maʻamau (HSDD) e like me keʻano o ka moekolohe piliʻole e pilikia ai ka pilikia a iʻole ka pilikino.

Ka hoʻohanaʻana i ka paukū Flibanserin (167933-07-5)

ʻO Flibanserin ka paukū kahi mea hanaʻino 5-HT1A a me ka 5-HT2A antagonist i hoʻolālāʻia no ka mālamaʻana i ka maʻi hōʻeuʻeu i ka wahine ma ka wahine (1,2).

Hōʻoiaʻia Flibanserin lulupa (167933-07-5) Hōʻike

100 mg i ka manawa hoʻokahi i ka wā e moe ai

Ka lōʻihi o ke kaukō: E hoʻopauʻia kēia lāʻau lapaʻau ma hope o nā wiki 8 ināʻaʻole hōʻike ka mea maʻi i ka holomua o nā hōʻailona.

Comments:ʻAʻole i hōʻikeʻia kēia lāʻau lapaʻau no ka hoʻonuiʻana i ka hanaʻana i ka wahine, aʻaʻole hōʻikeʻia no ka mālamaʻana i nā wāhine postemoe me nā kāne.

Nā hopena o ka Flibanserin pauku (167933-07-5)

He mea maʻalahi nā hanaʻino ma waena o nā wāhine e lawe ana i ka pauma flibanserin. ʻO ka hapa nui o nā hanana i hāʻule i ka haʻahaʻa. ʻO nā hanana kū'ēʻole i hōʻike pinepineʻia i kēia manawa,ʻo ia nō keʻano o ka nozziness, keusea, ka nāwaliwali, ka hiamoe, a me ka hiamoe e moe ana.

ʻO ka inu waiʻona i ka wai flibanserin ka hopena hiki ke hoʻohaʻahaʻa nui ke koko (ke kaheʻokoʻa i loaʻa nā hōʻailona ma hope o 2 mau aniani waina i hōʻea i 17%).

NA HALO A E HOOLAHA:

E kūʻai ʻia ana kēia ʻano mea no ka noiʻi noiʻi wale nō. Wahi a ke kūʻai aku. ʻAʻole no ka loiloi kanaka, ʻaʻole lāʻau lapaʻau, manu hoʻāno, a i ʻole e kōkua ʻia nā mea hale.


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ʻO Shangke Chemical he polokalamu kelehana kiʻekiʻe e kū nei i nā mea hana hana hoʻopihamaha hana (APIs). No ka mālamaʻana i ka maikaʻi i ka manawa o ka hanaʻana, kahi nui o nāʻoihana akamai, nā mea hana papa hana mua a me nā hale liʻiliʻi i nā kumu nui.

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