ʻO Nicotinamide riboside chloride (NR-CL) (23111-00-4)

March 11, 2020
SKU: 129938-20-1

ʻO Nicotinamide riboside (NR) kahi mea hou i ʻike ʻia ka nikotinamide adenine dinucleotide (NAD +) i ka vitamine. Nā …….


Kūlana: I ka Production Production
Mokuna: 25kg / Drum

Nicotinamide riboside chloride (NR-CL) (23111-00-4) wikiō

ʻO Nicotinamide riboside chloride (NR-CL) (23111-00-4) Snāʻike

Product Name ʻO Nicotinamide riboside chloride (NR-CL) (23111-00-4)
Hawaiian Name NRC; 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride; Nicotinamide ribose chloride; 3-Carbamoyl-1- (β-D-ribofuranosyl) pyridinium chloride; 3-carbamoyl-1 - ((2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyridin-1-ium chloride; Nicotinamide BD Riboside Chloride (WX900111); NR-CL;
Kāleka CAS 23111-00-4
InChIKey YABIFCKURFRPPO-IVOJBTPCSA-N
SMILE C1 = CC (= C [N +] (= C1) C2C (C (C (O2) CO) O) O) C (= O) N. [Cl-]
Ka Lā Molecular C11H15ClN2O5
Molecular Weight 290.7002
Monoisotopic Mass 290.066949 g / mole
Point Hoʻolālā N / A
kala like 'ole keʻokeʻo
Shoʻoweliweli temp -20 ° C Pākiho
noi i nā meaʻaiʻaiʻaiʻai, nā lāʻau lapaʻau

He aha ʻO Nicotinamide riboside chloride(NR-CL)?

ʻO Nicotinamide riboside (NR) kahi mea hou i ʻike ʻia ka nikotinamide adenine dinucleotide (NAD +) i ka vitamine. Kapa ʻia ka ʻano like me ka NR chloride i kapa ʻia ʻo NIAGEN, he ʻano synthetic o ka ribotide nikotinamide a he kumu kahi ia o ka nikotinamide ma ke ʻano o ka waikawa ʻo nikotinic ma ke bioavailable a ua manaʻo paʻa ia he palekana (GRAS). ʻO NR chloride ke kumuhana o nā meaʻaiʻai hou ʻelua no ka hoʻohana ʻana i nā mea kanu meaʻai.

ʻO Nicotinamide Riboside Chloride kahi mea hana maoli i loaʻa i ka waiū. Hoʻopili maoli ia ʻo niacin a me nā ʻano like ʻole o ka vitamina B3. Ua ʻike kekahi mau noiʻi he Nicotinamide Riboside Chloride kekahi mau hiʻohiʻona kūʻokoʻa e hiki ai ke hoʻonui i ka metabolism kekahi e kōkua i ka puhi ʻana i nā calorie hou a pale i ka loaʻa kālā. Ma kahi o ka lilo ʻana o ke kaumaha, kōkua nō hoʻi ia i ka hoʻoulu ʻana i ka hana o ka muse, hoʻonui i ka hiki ke hoʻolilo i ka hoʻolilo, a e hoʻemi i nā mea kūpono i ka maʻi maʻi.

Eia kekahi, he noiʻi i loko o nā kānaka i hōʻike ʻia e hoʻohaʻahaʻa ka Nikotinamide Riboside Chloride i nā pae NAD +, e kōkua ana i ka hoʻomaʻemaʻe i kekahi mau kūlana e pili ana i nā makahiki, ʻoiai ʻoi aku ka wikiwiki e ʻike akā pehea ia.

pomaikai o ʻO Nicotinamide riboside chloride(NR-CL)

ʻO Nikotinamide riboside chloride kahi hana syntact o ka ribotide nikotinamide, nā pono ona / hana like me ka nikotinamide riboside. Ua komo i ka metabolism i loko o ke kino, hiki ke hoʻohana e pale aku i ka maʻi pellagra a i ʻole nā ​​maʻi niacin defection a hoʻoemi i ka kolamu a me ka triglycerides i ke koko. Hoʻohana pū ʻia ia no ka hoʻohaʻahaʻa ʻana i ka hopena o ka hōʻeha o ka naʻau ma nā poʻe me ka cholesterol kiʻekiʻe e loaʻa ana i ka ʻeha puʻuwai. I kekahi manawa e hoʻohana ʻia e mālama ai i ka maʻi ʻalapau coronary (atherosclerosis), pale i ka pale ʻana i ka lolo a me ka ate (cardiovascular, diabetes, maʻi Alzheimer).

ʻO ka ʻokoʻa, ʻo Nicotinamide riboside chloride he pono ʻē aʻe i kekahi kanaka:

  • ʻO ka hoʻowalewale kūpono a me ka hoʻopili ʻana o nā protein a me nā momona;
  • Kōkua i ka hoʻololi ʻana i ka nui amino acid tryptophan i loko o ka niacin;
  • Hoʻemi i ka luaʻi, a hōʻemi i nā hopena o ka lawe ʻana i nā antidepressants ma muli o ka malo maloʻo a paʻakikī hoʻi ka ʻūhū ʻana;
  • Hoʻololi i ka syntatic acid synthesis a pale aku i ka wā kahiko o nā ʻiʻo a me nā ʻōpū, no laila e hoʻokō i ke kumu o ka lohi i ka wā kahiko;
  • Ka hoʻolōʻihi i ka huelo nocturnal hoonui, spaly paralysis a me nā wāwae a me nā wāwae;
  • Hoʻomaopopo i ka hypometabolism congenital a me ka hoʻonui ʻana o ka hana ʻaina;
  • ʻO ka pale a me ka mālama ʻana i ka pauʻa o ka vitamin B6;
  • Ka hopena o ka carpal tunnel syndrome;
  • Kōkua ka hoʻolilo ʻana i ke kaumaha a hoʻoikaika i ka hana pono.
  • E hoʻomaikaʻi i ka pale ʻana o ke kino i nā maʻi kanesa
  • Kāohi i ka nalo lohe
  • He diuretic kūlohelohe.
  • ʻO ka lawe ʻana i nā dosage nui e hiki ke hōʻoluʻolu i ka hoʻohui lāʻau a loaʻa iā ia kahi hopena detoxification maikaʻi.
  • E hoʻomaikaʻi i ka hana o nā pūʻumi epidermal, a me nā hana o nā mea ʻē aʻe o ke ʻano kino o ke kanaka, e mālama i ka ʻālamalama o ka ʻili.

ʻO Nicotinamide riboside chloride(NR-CL) hoʻohana

No ka mea ʻo ka Nicotinamide riboside chloride he mau lāʻau lapaʻau maikaʻi, ʻo ia ka mea i hoʻohana ʻia i nā mea kanu meaʻai, nā lāʻau lapaʻau a me ka mahina ʻai.

Reference:

  • Conze D, Brenner C, Kruger CL. ʻO ka palekana a me ka metabolism o ka hoʻokele wā lōʻihi o ka NIAGEN (Nicotinamide Riboside Chloride) i kahi Randomized, Double-Blind, Placebo-hoʻokolohua hoʻokolohua hoʻokolohua o nā pākaha momona. Sci Rep. 2019 Jul 5; 9 (1): 9772. doi: 10.1038 / s41598-019-46120-z. PMID: 31278280 PMCID: PMC6611812.
  • Bogan, KL, Brenner, C. (2008). "ʻO Nikotinic acid, ʻo nikotinamide, a me ka nikotinamide riboside: kahi loiloi molekole o NAD + mua o ka waiʻai i loko o nā meaʻai o ke kanaka". Annu. Rev. Nutr. 28: 115–130. doi: 10.1146 / annurev.nutr.28.061807.155443. PMID 18429699.
  • Chi Y, Sauve AA (Nowemapa 2013). "ʻO Nikotinamide riboside, kahi mea ʻai i loko o nā meaʻai, he vitamin B3 me nā hopena i ke kaola metabolism a me ka neuroprotection". ʻO Ke Kulanui ʻO Curr Opin Clin Nutr Metab. 16 (6): 657–61. doi: 10.1097 / MCO.0b013e32836510c0. PMID 24071780.