NADH 2Na (606-68-8)

Wikiō NADH 2Na (606-68-8)

ʻO Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) Mea Kūpili

He aha ia ʻo Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)?

ʻO NADH kahi ʻano o ka hoʻouka adenine nicotinamide (NAD) enzim, kahi ʻano coenzyme ikaika o kahi kikoʻī a me ka huaora B3. ʻO NADH (b-Nicotinamide adenine dinucleotide) Disodium Salt, hoʻemi ʻia, ʻike ʻia hoʻi ʻo Nicotinamide adenine dinucleotide, he coenzyme i loko o nā hopena redox. ʻO kāna mau hana me ka mea e hoʻomāhuahua ai i ka mea hoʻopili olakino ma nā hana catabolic e komo pū ana me ka glycolysis, β-oxidation a me ka citric acid cycle (Krebs cycle, TCA cycle). Hoʻopili pū ka paʻakai disodium o NADH i nā hanana hōʻailona hōʻailona, ​​e like me ka papahele no ka polymerases poly (ADP-ribose) i ka wā o ka pane ʻana o ka DNA. ʻO ia ka paʻakai disodium o NADH, ua hoʻohana ʻia i loko o kaʻai a me ka mea e pono ai i nā meaʻai i loko o ka mālama ʻana i ka maʻi o Parkinson, maʻi syndrome hōʻeha, ke maʻi Alzheimer a me nā maʻi cardiovascular.

Loaʻa iā Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)

Ma keʻano he coenzyme o oxidoreductases, nui ka paʻakai NADH disodium i kahi mea nui i ka hana o ke kino.

- Hiki ʻo NADH disodium salt i mea e alakaʻi aku ai i ka noʻonoʻo pono, noʻonoʻo pono, ʻike a me ka hoʻomanaʻo. Hiki ke hoʻonui i ka acuity noʻonoʻo a hoʻonui i ka manaʻo. Hiki iā ia ke hoʻonui i nā ikehu olakino ma ke kino a hoʻomaikaʻi i ka metabolism, ka mana o ka lolo a me ka hoʻomanawanui.

- E kōkua i nā poʻe me ka hōʻeha hau, ke koko kiʻekiʻe a i ʻole ke kolamu kiʻekiʻe;

- hoʻomaikaʻi i ka hana hoʻokūkū;

- Hoʻaleʻa i ke kaʻina hana kahiko a mālama i ka kūpaʻa o nā sela nerve e kākoʻo i ka wahī;

- Hiki ke mālama i ka maʻi o Parkinson, hoʻomaikaʻi i ka hana o nā neurotransmitters i loko o ka lolo o nā mea maʻi me ka maʻi o Parkinson, e hōʻemi ana i ka maʻi kino a me ka pono o ka lāʻau;

- E hoʻomaʻamaʻa i ka maʻi paleha o ka maʻi (CFS), kahi maʻi Alzheimer a me nā maʻi cardiovascular;

- Ke pale aku nei i nā hopena ʻaoʻao o kahi lāʻau maʻi maʻi i kapa ʻia ʻo zidovudine (AZT);

- Ke kū'ē i nā hopena o ka waiʻona ma ka ate;

- Māluhiluhi ma hope o ka lele 'ana

Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) nā hopena ʻaoʻao:

I kēia manawa, ʻike maluhia ka paʻakai ʻo NADH disodium no ka hapanui o ka poʻe inā hoʻohana kūpono kūpono a me ka manawa pōkole, a hiki i 12 mau pule. ʻAʻole ʻike ka hapa nui o kēlā me kēia hopena i ka wā e lawe ai i ka nui i ʻōlelo ʻia i kēlā me kēia lā, ʻo ia ʻo 10 mg.

Eia nō naʻe, ʻaʻole lawa nā datas e pili ana i ka hoʻohana ʻana o ka paʻakai disodium o NADH i ka wā hapai a me ka hānai holoholona. No laila, pono lākou e noho ma ka ʻaoʻao palekana a pale i ka hoʻohana ʻana.

Reference:

• Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - kahi ala hou e pili ana i ka maʻi o Parkinson. ʻO ka hoʻohālikelike o ka noi waha a me ka makua. Kui Hōʻea Acta Neurol 1993; 146: 32-5.
• Budavari S, ed. ʻO ka Mahuʻāina Merck. 12ā ed. Keena ʻOihana, NJ: Merck & Co., Inc., 1996.
• Bushehri N, Jarrell ST, Lieberman S, et al. Ua hōʻemi ʻia ʻo Oral ka B-nicotinamide adenine dinucleotide (NADH) i ke kahe o ke koko, lipid peroxidation, a me ka ʻaoʻao lipid ma nā kiʻī hypertensive (SHR). Geriatr Neprol Urol 1998; 8: 95-100.
• Bushehri N, Jarrell ST, Lieberman S, et al. Ua hōʻemi ʻia ʻo Oral ka B-nicotinamide adenine dinucleotide (NADH) i ke kahe o ke koko, lipid peroxidation, a me ka ʻaoʻao lipid ma nā kiʻī hypertensive (SHR). Geriatr Neprol Urol 1998; 8: 95-100.
• Castro-Marrero J, Cordero MD, Segundo MJ, et al. Hoʻonui anei ka waha i kahi coenzyme Q10 a me ka hoʻohui NADH i ka momona a me nā hiʻohiʻona biochemical ma ke akeʻeha o ka maʻi momona? Antioxid Redox Signal 2015; 22 (8): 679-85.
• Dizdar N, Kagedal B, Lindvall B. Ka mālamaʻana i ka maʻi o Parkinson me NADH. Acta Neurol Scand 1994; 90: 345-7.