NADH 2Na (606-68-8)

March 15, 2020
SKU: 129311-55-3

ʻO NADH kahi ʻano o ka nicotinamide adenine dinucleotide (NAD) enzyme, kahi ʻano coenzyme ʻeleu o kahi pūhui a me ka huaʻai B3 ……….

 


Kūlana: I ka Production Production
Hoʻonohonohoʻia a hoʻoponoponoʻia
nona iho: 1277kg / ka mahina

Wikiō NADH 2Na (606-68-8)

ʻO Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) Mea Kūpili

Product Name ʻO Beta-Nicotinamide adenine dinucleotide disodium paʻakai (NADH 2Na)
Hawaiian Name NADH (disodium paʻakai); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium Salt; Nicotinamide adenine dinucleotide, hōʻemi;
Kāleka CAS 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
SMILE C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Ka Lā Molecular C21H27N7Na2O14P2
Molecular Weight 709.4
Monoisotopic Mass 709.088661 g / mole
Point Hoʻolālā 140-142 ℃
kala like 'ole Melemele
Shoʻoweliweli temp 2-8 ℃
Palekana H2O: 50 mg / mL, maopopo i kahi akaka, ʻālani
noi Kauka; mea momona a me nā meaʻai e pono ai;

 

He aha ia ʻo Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)?

ʻO NADH kahi ʻano o ka nicotinamide adenine dinucleotide (NAD) enzyme, kahi ʻano coenzyme ʻeleu o kahi hui a me ka huaʻai B3. ʻO NADH (b-Nicotinamide adenine dinucleotide) Disodium paʻakai, hoʻemi ʻia, ʻike ʻia ʻo Nicotinamide adenine dinucleotide, kahi coenzyme i nā hopena redox. ʻO kāna mau hana ma ke ʻano he mea hāʻawi electron regenerating i nā kaʻina catabolic e like me glycolysis, β-oxidation a me ka pōʻai acid citric (pōʻaiapuni Krebs, pōʻaiapuna TCA). Ke komo pū nei ka paʻakai NADH disodium i nā hanana hōʻailona pūnana, no ka laʻana ma ke ʻano he substrate no ka poly (ADP-ribose) polymerases (PARPs) i ka wā o ka DNA hōʻino pane. E like me ka paʻakai disodium o NADH, hoʻohana ʻia ia i ka papaʻai a me nā mea hoʻopili pono i ka mālama ʻana i ka maʻi o Parkinson, ka maʻi luhi mau loa, ka maʻi ʻo Alzheimer a me nā maʻi puʻuwai.

 

Loaʻa iā Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)

Ma ke ʻano he coenzyme o nā oxidoreductases, hana nui ka paʻakai NADH disodium i ka hana ikehu o ke kino.

- NADH disodium paʻakai hiki ke alakaʻi i ka maikaʻi o ka noʻonoʻo, ka makaʻala, ka noʻonoʻo, a me ka hoʻomanaʻo. Hiki ke hoʻonui i ka noʻonoʻo noʻonoʻo a hoʻonui paha i ke ʻano. Hiki ke hoʻonui i nā pae ikehu i ke kino a hoʻomaikaʻi i ka metabolism, ka mana o ka lolo a me ka hoʻomanawanui.

- Kōkua i ka poʻe me ke kaumaha o ka maʻi, ke koko kiʻekiʻe a i ʻole ke kiʻekiʻe o ka cholesterol;

- Hoʻonui i ka hana haʻuki;

- Ke hoʻopanee i ke kaʻina hana ʻelemakule a mālama i ka pono o nā hunaola nerve e kākoʻo i ka ʻōnaehana ʻōiwi;

- Hiki ke mālama i ka maʻi o Parkinson, hoʻomaikaʻi i ka hana o nā neurotransmitters i ka lolo o nā mea maʻi me ka maʻi ʻo Parkinson, hoʻemi i ke kīnā ʻole o ke kino a me nā pono lāʻau.

- Hoʻohālikelike i ka maʻi luhi mau loa (CFS), ka maʻi o Alzheimer a me ka maʻi maʻi maʻi;

- Palekana i nā hopena ʻino o kahi lāʻau lāʻau AIDS i kapa ʻia zidovudine (AZT);

- Kūʻē i nā hopena o ka waiʻona ma ke akepaʻa;

- Luhi i ka huakaʻi

 

ʻO Beta-Nicotinamide adenine dinucleotide disodium paʻakai (NADH 2Na) nā hopena ʻaoʻao:

I kēia manawa, ʻike maluhia ka paʻakai ʻo NADH disodium no ka hapanui o ka poʻe inā hoʻohana kūpono kūpono a me ka manawa pōkole, a hiki i 12 mau pule. ʻAʻole ʻike ka hapa nui o kēlā me kēia hopena i ka wā e lawe ai i ka nui i ʻōlelo ʻia i kēlā me kēia lā, ʻo ia ʻo 10 mg.

Eia nō naʻe, ʻaʻole lawa nā datas e pili ana i ka hoʻohana ʻana o ka paʻakai disodium o NADH i ka wā hapai a me ka hānai holoholona. No laila, pono lākou e noho ma ka ʻaoʻao palekana a pale i ka hoʻohana ʻana.

 

Reference:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - kahi ala lapaʻau hou i ka maʻi o Parkinson. Hoʻohālikelike o ka noi waha a me ka makua. Acta Neurol Scand Suppl 1993; 146: 32-5.
  • Budavari S, hoʻoponopono. Ka Papa Kuhikuhi Merck. 12th ed. Whitehouse Station, NJ: Merck & Co., Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Ua hōʻemi ʻia ʻo Oral ka B-nicotinamide adenine dinucleotide (NADH) i ke kahe o ke koko, lipid peroxidation, a me ka ʻaoʻao lipid ma nā kiʻī hypertensive (SHR). Geriatr Neprol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Ua hōʻemi ʻia ʻo Oral ka B-nicotinamide adenine dinucleotide (NADH) i ke kahe o ke koko, lipid peroxidation, a me ka ʻaoʻao lipid ma nā kiʻī hypertensive (SHR). Geriatr Neprol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Hoʻonui anei ka waha i kahi coenzyme Q10 a me ka hoʻohui NADH i ka momona a me nā hiʻohiʻona biochemical ma ke akeʻeha o ka maʻi momona? Antioxid Redox Signal 2015; 22 (8): 679-85.
  • ʻO Dizdar N, Kagedal B, Lindvall B. Hoʻomaʻamaʻa ʻana i ka maʻi o Parkinson me NADH. ʻO Acta Neurol Scand 1994; 90: 345-7.