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ʻO ka Nicotinamide mononucleotide (NMN) paheʻe (1094-61-7)

Nō Nicotinamide Mononucleotide (NMN) ka lepo e hoʻopau i ka waiwai o ke kino e pili ana i nā makahiki.


Kūlana: I ka Production Production
Mokuna: 25kg / Drum
nona iho: 1370kg / ka mahina

Description

NĀ NĀ NĀ MĀKU NĀ NĀ MANAʻO NĀ NĀ LIMA (1094-61-7)

ʻO ka Nicotinamide mononucleotide (NMN) paheʻe (1094-61-7) Hōʻike

ʻO ka Nicotinamide Mononucleotide kahe ("NMN" a me "β-NMN") he nucleotide i loaʻa mai ka ribose a me ka nicotinamide. E like me ka riboside nicotinamide, NMN ka waiwai o ka lolocin, a he mau enzymes nā kānaka e hiki ke hoʻohana i ka NMN e hana i ka adinine dinucleotide (NADH).

No ka mea he mea hana ka NADH no nā hana i loko o ka mitochondria, no nā sirtuins, a no ka PARP, ua aʻoʻiaʻo NMN i nāʻano holoholona e like me keʻano o nā neuroprotective a me nā anti-kahiko. Ua kālepa ikaika nā pāʻoihana'eneke DM ma nā huahana NMN e koi ana i kēlā mau pōmaikaʻi, akā naʻeʻaʻole i hoʻomauʻia kahi aʻo pilikino ma luna o nā kānaka.

ʻO ka Nicotinamide mononucleotide (NMN) paheʻe (1094-61-7) Hōʻike

Product Name ʻO ka Nicotinamide Mononucleotide (NMN) ka pauka
Hawaiian Name ʻO ka monophosphate Beta-nicotinamide; Raw Nicotinamide Mononucleotide lūlū; AC1Q6RVF; AC1L23AN; NMN (+); ʻO SCHEMBL6858129
Brand Name ʻO Mirailabo
Kōpana Drug Pākuʻi Dietary
Kāleka CAS 1094-61-7
InChIKey DAYLJWODMCOQEW-TURQNECASA-N
hakakino F'Oula C11H15N2O8P
hakakino Wʻewalu 334.22
Monoisotopic Mass 335.229 g / mole
Hoʻolaha Pʻo kaʻaila > 96 ° C
Fkū hou Pʻo kaʻaila ʻAʻohe lā i loaʻa
ʻO ka Halifa-Ola No laila, e like me ka mea i hōʻikeʻia ma nā Fig. 3, ua nalowale ka nicotinamide mai ke koko me ka hapalua o nā hola 5.3, akāʻo ka hapalua o ka waikawa nicotinic he 1.1 hola.
kala like 'ole ʻO ka'ōmaʻomaʻo i ka paukūʻeleʻele
Solakino Ka Methanol (Ma kahi liʻiliʻi), ka wai (Ka liʻiliʻi)
Ska hoʻokele Tka mahana ʻO Hygroscopic, -20˚C Pūʻali Palekana, ma lalo o ka'Ineneʻe Inert
Apaukū No ke pāʻani i ka hana o ke ola lōʻihi a me ka mālamaʻana i ka maʻi

ʻO Nō Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Hōʻike

ʻO ka Nicotinamide Mononucleotide kahe ("NMN" a me "β-NMN") he nucleotide i loaʻa mai ka ribose a me ka nicotinamide. E like me ka riboside nicotinamide, NMN ka waiwai o ka lolocin, a he mau enzymes nā kānaka e hiki ke hoʻohana i ka NMN e hana i ka adinine dinucleotide (NADH).

Nānā houʻia nā noiʻi hou e hiki i ka NMN ke hoʻoulu hou i ka pilikino pūnaewele, a loaʻa i nā hopena koʻikoʻi koʻikoʻi. ʻO ka hopena ma ke kino, NMN (β-Nicotinamide mononucleotide) he mea nui no ka hoʻololiʻana i nā meaʻai i ka ikehu. ʻO ka hōʻoiaʻana i ka NMN ma keʻano he mahele o kāu hana i kēlā me kēia lā e hiki ke hāʻawi i ka ho'ōla ike, ka palekana mai ka'ōpiopio o kaʻelemakule, a emi iho ka pilikia o ka pilikia o ka maʻi. ʻO NMN kekahi kumuhana i nā hana hou, kahi hana koʻikoʻi i ka hana hana i ka hoʻokumuʻiaʻana o ATP i ka molemoʻokumu wai ikaika. Loaʻa i ka NMN kahi'āpana kōkua hoʻonāhui e ho'āla ai i ka pololei a me ka lōʻihi.

Hoʻohana o Nicotinamide Mononucleotide (NMN) powder (1094-61-7)

  1. ʻO Nicotinamide Mononucleotide i loko o nā pūnaewele kanaka kahi i koʻikoʻi nui i ka hanauna hanahana, ua pili i loko o ka NAD intracellular (nicotinamide adenine dinucleotide, ka hoʻoikaika i ka hoʻoikaika i ka hoʻohui i ka coenzyme koʻikoʻi) ka hoʻomanaʻo, hoʻohanaʻia i loko o kaʻelemakule, hāʻule i ke koko koko a me nā huahana ola kino.
  2. ʻO Nicotinamide Mononucleotide he huama wai e hoʻonoeʻia ka wai,ʻO ka hua keʻokeʻo keʻokeʻo o ka crystalline, odorlessʻole kokoke i ke kinoʻole,ʻawaʻawa ma ke keʻa, me kaʻoluʻoluʻole i ka wai a me ka hanana, kahi eʻoluʻolu ai i ka glycerin.
  3. Nō Nicotinamide Mononucleotidepowderis hiki ke maʻalahi i ka waha, a hiki ke hoʻomāhelehele nuiʻia i loko o ke kino, hoʻopuka kokeʻia nā mīkini metabolites a me ka pahuhopu mai ka mimi. ʻO Nicotinamide ka hapa o ka coenzyme I a me ka coenzyme II ka hana o ka hāmole hydrogen i ke kolamu'opihu oxygenation, hiki ke hoʻoulu i nā hana olaola olaola a me nā mea e pono ai ka mālamaʻana, mālama i nāʻili maʻamau (ʻo kaʻili, ka'ōpala me nā'ōpiopio) he kuleana koʻikoʻi.

Eia kekahi, loaʻa ka nicotinamide i ka paleʻana a me ka mālamaʻana i ka poho o ka puʻuwai, ka node o ka hewa, a me ka ho'āʻo hōʻalo wikiwikiʻana, hiki i ka nicotinamide ke hoʻomaikaʻi nui i ka puʻuwai o ka naʻau a me ka poho o ka ululāʻau e hanaʻia e nā kāhili.

maika ʻO Nicotinamide Mononucleotide (NMN) powder (1094-61-7)

  • Nānāʻo NMN i ka Power Metabolism - NAD + kōkua i ka hōʻokiʻana i nā meaʻai e like me nā meaʻai i ka ikehu.
  • Hoʻonui i ka maʻi olakino a me ka hana Cardiovascular.
  • Ka HanaʻAi'Aiwi DNA - Ua hoʻohanaʻiaʻo NAD + no ka hoʻoponoponoʻana i nā kaula DNA i haki.
  • NĀ KAHUHI SIRTUIN -ʻO NAD + e koiʻia no ko mākou mau ola lōʻihi e hana.
  • ʻO NMN ka pūnaewele i hoʻohanaʻia e Harvard Scientists e hoʻololi i kekahi mau hōʻailona o nā meaʻelemakule i loko o nāʻiole i hoʻomaka i ka holo i nā mea hoʻopiha NAD.
  • Mālama ka mālama NMN i kaʻeha o ka lolo ma ka cICH
  • Nā NMN Pūkino e hoʻopakele i nā pilikia pilikia
  • Hoʻopilikiaʻo Nicotinamide mononucleotide i ka hoʻololiʻana o JNK e hoʻololi i ka maʻi Alzheimer
  • Hiki i ka NMN ke hoʻouka hou i ka loiloi i nā kolemo AD

Hōʻoiaʻo Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Hoʻoponopono

ʻO keʻano o ka lawelaweʻana o Nicotinamide mononucleotide ka paukū ma kahi o 250 - 1500 mg i kēlā lā.

Hoʻomaʻamale kokeʻia ka NMN me ka hapa iki o ke ola, no laila e mālamaʻia nā kūlana NAD + no ka nui o ka lā e hiki ke'ōleloʻia e lawe i kahi 125 mg capsule i ka ala a me kekahi ma ke awakea inā e lawe iā 250 mg i kēlā lā.

Nā hopenaʻaoʻao ʻO Nicotinamide Mononucleotide (NMN) powder (1094-61-7)

ʻOiaiʻo Nicotinamide mononucleotide (NMN) lepo kahi mea hou a me ka noiʻi e hoʻomauʻia ana, ua hanaʻia nā haʻawina i hanaʻia i kēia manawa a he mea palekana loa aʻaʻoleʻawaʻawa.

ʻO nā hopena o ka hopena he mea maʻamau, akā, uaʻikeʻia i kahi o kaʻeleʻele, dizziness, sweating, a me ka neusea.

NA HALO A E HOOLAHA:

E kūʻai ʻia ana kēia ʻano mea no ka noiʻi noiʻi wale nō. Wahi a ke kūʻai aku. ʻAʻole no ka loiloi kanaka, ʻaʻole lāʻau lapaʻau, manu hoʻāno, a i ʻole e kōkua ʻia nā mea hale.


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Nāʻike & nā hua'ōlelo huahana

2019 Nā mea hōʻailona hōʻailona hōʻoia: Nicotinamide Mononucleotide (NMN)

E hoʻomaopopo '

  1. Mills, KF, Yoshino, J., Yoshida, S., et al. (2016). Ka Manaʻo Lō Loa o Nicotinamide Mononucleotide Mitigates Ke Kinoʻana o ka Mīkini Maʻemaʻe Makahiki i ka Mice. ʻO ka pūnaewele kāpili.
  2. Yoshino, J., Mills, KF, Imai, SI a me Yoon, MJ (2011). ʻO Nicotinamide Mononucleotide, he kīʻo NAD + Intermediate, Ke Kānāʻia nei ka Pathophysiology o ka Mīkini Ola Maʻemaʻe a me ka Makahiki ma Mice. ʻO ka pūnaewele kāpili.
  3. Yamamoto, T., Byun, J., Zhai P., Ikeda, Y., Oka, S., a me Sadoshima, J. (2014). ʻO Nicotinamide Mononucleotide, he Intermediate o NAD + Synthesis, Hoʻomalu i ke Kino mai ka Ischemia a me ka Reperfusion.
  4. Sinclair, DA, Uddin, GM, Youngson, NA, a Morris, MJ (2016). ʻO ke poʻo i ka poʻo ke kūlike o ka hōʻailona pōkole me NAD + precursor Nicotinamide Mononucleotide (NMN) a meʻeono mau wiki o ka hoʻolālā i loko o ka Obese Female Mice.
  5. Imai, S., Yoshino, J., Mills, KF, Grozio, A., et al. (2019) Slc12a8 he Nicotinamide Mononucleotide Transporter. ʻO ka Nature Metabolism.
  6. De Picciotto, NE, Mills, KF, Imai, S., Gano, LB, a me al. (2016). Nā Nicotinamide Mononucleotide Reverses Ka Lēkiʻi Vascular a me ka Hana Māmā me nā Mice Aging.
  7. Yao, Z., Gao, Z., Yang, W., a me Iia, P. (2017). Hoʻopiʻiʻo Nicotinamide Mononucleotide i ka JNK Hoʻopiliʻia e hoʻokahuli i ka maʻi Alzheimer.
  8. Hou, Y., Wang, Y., Zhang, Y., Lautrup, S., et al. (2018). NAD + Hoʻohui Kūwaho Kūkākūkā i nā Māhele Alzheimer Key a me nā Damage Nā DNA i nā pane ma kahi Hōʻailona Moemoeke Hou me ka Hoʻoponopono Hānaika DNA i hoʻokomoʻia.

ʻO Shangke Chemical he polokalamu kelehana kiʻekiʻe e kū nei i nā mea hana hana hoʻopihamaha hana (APIs). No ka mālamaʻana i ka maikaʻi i ka manawa o ka hanaʻana, kahi nui o nāʻoihana akamai, nā mea hana papa hana mua a me nā hale liʻiliʻi i nā kumu nui.

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