Paukū Spermidine
Loaʻa iā Phcoker ka hiki ke hana nui a me ka hoʻolako ʻana i ka pauka Spermidine ma lalo o ke ʻano o cGMP.
ʻO Spermidine kahi huahana kūlohelohe, i hoʻokaʻawale ʻia i ka polyamine. Hoʻomaka ka emi ʻana o nā pae spermidine i loko o ko mākou kino me ka makahiki, no laila ua ʻōlelo ʻia e hoʻopiha iā lākou me ka supplementation. Hiki i nā mea spermidine ke ho'ōki i ke kaʻina hana maoli o ka ʻelemakule a me ka hakakā ʻana i nā maʻi e pili ana i ka ʻelemakule.
ʻO Spermidine kahi mea hou ma ka mākeke hoʻohui no ka anti-aging a me ka lōʻihi. Hiki ke kiʻi ʻia ka pauka spermidine extract mai ka Wheat Germ, akā ʻoi loa ka haʻahaʻa o ka spermidine i loko, ʻoi aku paha ma mua o 0.1% i ka maʻemaʻe.
Hoʻokumu ʻia ka Spermidine mai kona precursor, ka putrescine pūhui i loko o ke kino. ʻO Putrescine ka mea mua no ka spermine, kekahi polyamine i mea nui no ka hana kelepona. ʻO ka putrescine a me ka spermidine ke kōkua i ka ulu a me ka hana o ke kino. Pehea? Hiki i nā polyamines ke hoʻopaʻa i nā molekole like ʻole, a ma laila lākou e hoʻoikaika ai i ka ulu ʻana o ka cell, ke kūpaʻa DNA, ka hoʻonui ʻana o ka cell, a me nā kaʻina apoptosis. ʻIke ʻia hoʻi ka hana like ʻana o nā polyamines me nā mea ulu i ka wā o ka māhele cell.
E like me kā mākou e ʻike ai, hiki i ka putrescine ke hana i ka spermidine ma ke ʻano he kaʻina hana e wāwahi ai ka putrescine i ka decarboxylated S-adenosylmethionine.
He kuleana koʻikoʻi ia i ka hoʻoponopono ʻana i nā kaʻina hana olaola like ʻole, me nā pae o ka pH intracellular a me ka mālama ʻana i ka hiki o ka membrane cell. He kuleana koʻikoʻi ka Spermidine i kekahi mau kaʻina hana koʻikoʻi koʻikoʻi, me nā mea hoʻokipa aspartate, cGMP/PKG alahele hoʻāla, nitric oxide synthase, a me ka hana cerebral cortex synaptosome.
He mea hoihoi ka Spermidine i ka poʻe ʻepekema i ka pōʻaiapili o ka ʻelemakule no ka mea ʻo ia kahi mea hoʻoholo morphogenetic koʻikoʻi no ke ola o nā cell a me nā ʻiʻo ola [3].
ʻO ka hiki i ka spermidine ke hoʻoulu i ka autophagy i manaʻo ʻia ʻo ia ke kumu nui e ʻike ʻia e hoʻolōʻihi i ka ʻelemakule a kākoʻo i ka lōʻihi [4].
Ua hōʻike ʻia i ka hoʻoulu ʻana i ka autophagy i loko o nā ʻiole ate, nā ilo, ka hū a me nā lele [5].
ʻO kahi mīkini autophagy kīnā ʻole a me ka nele o ka spermidine e hoʻopili nui ʻia me ka emi ʻana o ke ola, ke koʻikoʻi mau, a me ka ʻeha nui.
He aha ka Spermidine trihydrochloride pauka?
ʻO Spermidine trihydrochloride pauka, ʻo ia ke ʻano trihydrochloride o spermidine. Aia ka waihona Spermidine ma ke ʻano wai, ʻoiai ʻo Spermidine trihydrochloride ma ke ʻano pauka. ʻO Spermidine trihydrochloride kahi ʻano kūpaʻa ʻoi aku ka paʻa o ka spermidine. ʻO Spermidine trihydrochloride powder benfits like me nā pono Spermidine.
He aha ka Wheat Germ Extract 1%?
Loa'a ka nui o ka Spermidine i loko o ka hua hua hua hua, he 1% ka spermidine. He mea pono ka Spermidine i loko o ka hua palaoa i ka lohi i ka ulu ʻana o ka maʻi kanesa a hoʻonui i ke olakino cardiovascular. Loaʻa iā ia nā antioxidants a hiki ke hoʻomaikaʻi i kou palekana holoʻokoʻa.
Hana ʻo Autophagy ma ke ʻano he lawelawe hoʻolei ʻōpala kelepona. Kōkua kēia polokalamu hoʻomaʻemaʻe ponoʻī i nā cell ma o ka wehe ʻana i nā mea āpau mai nā protein i hōʻino ʻia a i ʻole i hoʻopili hewa ʻia i nā organelles holoʻokoʻa a laila hana hou iā lākou. He kuleana koʻikoʻi kēia no ka mea ua hoʻopilikia maikaʻi ʻia nā mea kelepona i hōʻino ʻia i ke olakino cell a i nā hihia koʻikoʻi hiki ke hōʻeha nui.
Mālama pū ʻo ia i kāu mau cell mai nā pūhui ʻino e like me nā radical manuahi. Loaʻa i ka Spermidine nā waiwai anti-kahiko no ka mea e hoʻonui ai i ka hoʻoikaika kino i loko o kou kino. No ka laʻana, hoʻomaikaʻi ia i ke olakino o ka puʻuwai a me ka lolo, e hoʻohaʻahaʻa i ka hiki ʻana o nā maʻi pili makahiki. Hiki iā ʻoe ke hoʻonui i ka pae Spermidine āu e lawe ai i kēlā me kēia lā ma ka lawe ʻana a kūʻai aku i ka pauka hoʻohui Spermidine.
Hiki ke hoʻoheheʻe ʻia ka Spermidine i ka wai, ʻo ka holoi ʻana i ka wai e hōʻemi nui i ka spermidine i ka meaʻai.
Laulaha:
He haʻahaʻa ka hua i loko o ka spermidine, ʻo ka mea lanakila he mango me ka 3 mg/100g ʻiʻo a me ka iʻa he haʻahaʻa i ka spermidine, ʻo ka mea lanakila he pipi minced me 4mg/100g nati a me nā hua maloʻo he haʻahaʻa i ka spermidine: ʻo ka mea lanakila he hazelnuts me 2mg/100g. He haʻahaʻa nā huaʻai i ka spermidine, ʻo ka mea lanakila ka kulina me 3mg/100g
24.3 mg/100g hua huapalaoa
19 mg / 100g cheese cheddar
6 - 14 mg/100g pī
19 mg/100g ʻulaʻula
2- 10 mg/100g broccoli a me ka pua pua
9 mg/100g Champignons de Paris nā haloo
3 mg/100g mango
3 mg/100g moa
3 mg/100g kulina
2 mg/100g celery a me ka melon
2 mg/100g palaoa palaoa
ʻOiai e loaʻa ana ka spermidine i nā meaʻai holoʻokoʻa, hiki ke lawe ʻia ma ke ʻano hoʻohui - ke ala maikaʻi loa e mālama ai i kāu mau spermidine pae. Nui nā mea hoʻohui spermidine no ke kūʻai aku ma ka pūnaewele, e kiʻi i nā hopena maikaʻi loa, kūʻai i ka huahana mai ka mea hoʻolako Spermidine kūpono.
Loaʻa i nā mea hoʻohui Spermidine ka maikaʻi o ka loaʻa ʻana o ka nui o ka mea hana. ʻO nā kumu kūlohelohe, ma ka ʻaoʻao ʻē aʻe, aia i ka nui o nā ʻano kūlohelohe. No laila, ʻo ka pauka spermidine trihydrochloride kiʻekiʻe kāu koho maikaʻi loa inā makemake ʻoe e uku pono i ka emi ʻana o ka spermidine pili makahiki.
Hana ʻia ka ʻelemakule o ke kelepona i ka wā e hewa ai ke kaʻina hana maoli o autophagy, ʻo ia hoʻi ka hana hou ʻana o nā cell i pōʻino. ʻO Spermidine, ma ke ʻano he autophagy modulator, hiki ke lilo i mea kaua kūpono e kūʻē i ka ʻelemakule. E emi ana ka nui o ka spermidine me ka makahiki. ʻO ka lawe ʻana i ka pauka spermidine supplement e pili ana i ka ʻelemakule a hoʻemi i ka helu o nā radical manuahi.
Ka ulu ʻana o ka spermidine a me ka lauoho
Ua hōʻike ka noiʻi ʻana i ka hoʻohana ʻana i nā mea hoʻohui spermidine hiki ke hoʻoikaika i ka ulu lauoho. No ka laʻana, ua hōʻike ʻia kahi noiʻi o 100 mau kānaka olakino e hoʻolōʻihi i ka manawa o ka ulu ʻana o ka lauoho i kapa ʻia ʻo ka anagen phase. ʻOi aku ka lōʻihi o ka noho ʻana o ka lauoho lauoho i ka manawa anagen, ʻoi aku ka lōʻihi o ka ulu ʻana o ka lauoho. Ua hōʻike pū ʻia ka noiʻi ʻana i nā paipu hoʻāʻo i ka spermidine e hoʻoulu i ka ulu lauoho kanaka.
Hoʻomaikaʻi ʻo Spermidine i ke olakino Cardiovascular
Ua hōʻike ʻia ʻo Spermidine mai nā kumu meaʻai e lawe mai i nā hopena cardioprotective ma o autophagy, e like me nā haʻawina i nā ʻiole, nā ʻiole, a me nā kānaka e hōʻike ana i ka emi ʻana o ka hypertension a me ka ʻelemakule arterial. Pēlā nō, pili ka hoʻonui ʻia ʻana o ka spermidine me ka emi ʻana o ke koko a me ka liʻiliʻi o ka maʻi cardiovascular, e alakaʻi ana i ka make haʻahaʻa o ke kanaka.
Pono ka Spermidine no ka pale ʻana i ka maʻi kanesa
Ma waho aʻe o ka hoʻonui ʻana i ke ola, a hiki i ka 25%, ua hōʻike ʻia ka noiʻi ʻana i nā ʻiole i ka hoʻemi ʻana o ka spermidine supplementation i ka fibrosis ate a me ka maʻi kanesa, ʻoiai i nā kumuhana i ʻike ʻia i nā kemika e hoʻoulu ai i ka fibrosis ate. Hoʻopili pū nā haʻawina nānā kanaka i ka ʻai ʻana o ka spermidine meaʻai me ka emi ʻana o ka pilikia o ka maʻi maʻi ʻaʻai. Ke lawe ʻoe i nā mea hoʻohui Spermidine i hana ʻia me ka pauka spermidine trihydrochloride, e hele lōʻihi ana ʻoe i ka pale ʻana i kou kino mai ka maʻi kanesa. Hiki iā ʻoe ke hoʻohana i nā mea hoʻohui Spermidine i ka wā o ka mālama ʻana i ka maʻi kanesa.
Hiki i ka Spermidine ke ho'ēmi i ka emiʻana o ka naʻau
ʻO ka noiʻi i paʻi ʻia ma 2021 i loko o ka puke moʻolelo ʻo Cell Reports e hāʻawi i kahi moʻolelo kikoʻī o ka spermidine meaʻai e hoʻomaikaʻi ai i ka cognition a me ka hana mitochondrial i nā nalo a me nā ʻiole, me kekahi mau ʻikepili kanaka e hiki mai ana i luna [13]. ʻOiai he mea hoihoi kēia haʻawina, loaʻa iā ia kekahi mau palena, a pono nā ʻikepili pane hou aku ma mua o ka hiki ke hana ʻia kahi hopena paʻa e pili ana i nā pōmaikaʻi i ka ʻike kanaka. ʻO ka lawe ʻana i ka pauka spermidine supplement hiki ke hoʻohuli i nā pōʻino neuron i kumu ʻia e ka mumū, ke kaumaha oxidative, a me ka ischemia.
Spermidine a me ke kaumaha
ʻOiai he mea nui ka spermidine i ka hoʻokumu ʻana i nā mea momona, ʻaʻohe meaʻai (a i ʻole nā mea hoʻohui) i loaʻa i kēia mea e hoʻoikaika i ke kaumaha. Pēlā nō, ʻaʻole hiki i kekahi ke ʻōlelo inā hoʻonui kēia mea i ka metabolism. Loaʻa ka noiʻi kanaka e pili ana i ka pohō kaumaha a me ka helu metabolic.
Hiki ke hoʻoheheʻe ʻia a paʻa i ka wai, me ka bioavailability kiʻekiʻe.
ʻOi aku ka nui aʻe, kahi noiʻi o kēia manawa e nā virologists ma Berliner Charité e ʻimi nei i ka hiki o ka spermidine e pili ana i ke kumuhana nui o COVID-19. Ua ʻike mākou mai ka noiʻi mua ʻana e hoʻololi ka coronavirus i ka metabolism cell holoʻokoʻa, ka hopena i ka emi ʻana o nā pae spermidine, ma waena o nā hopena ʻē aʻe. ʻO kēia ka mea e pale ai i ke kaʻina o ka hoʻolei ʻana i ka ʻōpala kelepona (autophagy). Ma ka noiʻi Kelemania i ʻōlelo ʻia ma luna, ua mālama ʻia nā cell i loaʻa i ka coronavirus me ka spermidine, me ka hopena o ka hoʻonui ʻana o ka maʻi maʻi ma kahi o 85%. Ua hōʻike pū ʻia kahi noiʻi mua a Professor Simon o Oxford e hoʻoikaika ka spermidine i nā pane antiviral o ka ʻōnaehana pale. No laila he ʻelua aces i ka spermidine i ka wā e hakakā ai i ka coronavirus: (a) kaohi ʻana i ka hoʻolaha ʻana o ka maʻi virus a (b) hoʻoikaika i ka pane antiviral immune. Akā, pono mākou e kali a ʻike - e koi ʻia nā noiʻi kikoʻī kikoʻī ma mua o ka hiki iā mākou ke huki i nā hopena paʻa.
E ʻike nui ʻoe i ka palaoa germ extract spermidine powder capsules ke hoʻāʻo ʻoe e ʻimi i nā mea hoʻohui spermidine - akā ʻaʻole maʻamau kēia mau mea. ʻAʻole helu ka hapa nui i ka nui o ka spermidine iā lākou. Hāʻawi ʻo Phcoker i ka pauka spermidine trihydrochloride nui. ʻO ka pauka spermidine supplement maikaʻi loa me ka maʻemaʻe kiʻekiʻe a me ka bioavailability.
ʻO kā mākou hui ma ke ʻano he hale hana hana e hāʻawi i nā kumukūʻai nui a me nā kumukūʻai kūʻai nui e pili ana i ka pauka spermidine trihydrochloride a me Spermidine.
Loaʻa ka Spermidine i ka nui o nā meaʻai a mākou e ʻai ai. A ʻo ka mea ʻoiaʻiʻo, ʻo kā mākou Wheat Germ Extract Powder (Spermidine) 1% i lawe ʻia mai ka hua palaoa. Eia nō naʻe, ʻaʻole loaʻa pinepine iā mākou ka mea e pono ai mākou mai ka meaʻai wale nō, ʻoi aku ka nui o ko mākou mau makahiki a makemake nui ko mākou kino i nā meaʻai. ʻO kēia kahi e hiki ai i nā mea hoʻohui ke komo i ke kākoʻo i ke kino olakino.
He palekana anei ka lawe ʻana i ka spermidine?
ʻAe, he huahana kūlohelohe ia i loko o ke kino a he ʻāpana o kā mākou meaʻai kūlohelohe. Hōʻike ka ʻikepili i ka hoʻohui ʻana i ka spermidine me ka hoʻohana ʻana i ka pauka spermidine trihydrochloride ka palekana a me ka ʻae maikaʻi.
Hoʻopau anei ke kuke i ka spermidine?
I ka hihia o kekahi mau hana kuke e pili ana i nā wela kiʻekiʻe (53) i wehewehe ʻia ʻo ka ʻala ʻana, ka ʻai ʻana, a i ʻole ka palai ʻana i hana i nā poho a hiki i ka 60% o ka spermidine a me ka spermine i loko o ka ʻiʻo moa.
I ka manawa hea wau e lawe ai i nā mea hoʻohui spermidine?
Ua hōʻike ʻia kekahi mau hoʻokolohua he palekana loa ka 1.2 mg o spermidine i kēlā me kēia lā. Inā hana ʻia kēia i ke kakahiaka, i ke awakea a i ke ahiahi paha, e pili ana i kāu makemake pilikino, akā paipai mākou e lawe mau i ka manawa like o ka lā.
He spermidine anei ka sperm?
Ua ʻike mua ʻia ʻo Spermidine i loko o kahi laʻana o ka semen i ka makahiki 1687 e ka microscopist Dutch kaulana ʻo Anton Van Leeuwenhoek, no laila ka inoa. Eia naʻe, loaʻa ia i loko o nā cell eukaryotic a pau. Aia ka Spermidine ma lalo o ka Semen.
Pono au e lawe i nā mea hoʻohui spermidine?
Hōʻike nā haʻawina mua e hiki ke kōkua i ka ʻai waiwai nui o ka spermidine i ke ola lōʻihi. ʻO ka lawe ʻana i nā mea hoʻohui spermidine i kēlā me kēia lā i kou mau makahiki he ala palekana ia e pale aku ai i nā maʻi pili i ka makahiki a hāpai i ke olakino holoʻokoʻa.
Hiki i ka spermidine ke hoʻihoʻi i ka wā kahiko?
Hiki i ka lako waho o ka polyamine spermidine maoli ke hoʻolōʻihi i ke ola o nā mea hoʻohālike e like me ka hū, nā nematodes, nā nalo a me nā ʻiole. Hōʻike nā hōʻike epidemiological hou i ka hoʻonui ʻia ʻana o ka spermidine me ka meaʻai e hōʻemi ana i ka nui, ka maʻi cardiovascular a me ka maʻi kanesa pili i ke kanaka.
ʻEhia ka nui o ka spermidine i loko o ka paʻakai kahiko?
ʻOi aku ka nui o ka paʻakai, ʻoi aku ka nui o nā polyamines i loko.
ʻO Spermidine ka mea like. Loaʻa i ka paʻakai makua ka awelika o 10 mg o spermidine no 100 g o ka meaʻai, e like me nā loiloi 2011. No laila ke hōʻoia nei nā kānaka ʻepekema mai Graz i ka paʻakai paʻa i ka hopena maikaʻi no ka puʻuwai, akā kuhikuhi pū kekahi i ka momona momona.
Hiki iaʻu ke lawe i ka spermidine ma ka ʻōpū ʻole?
I kekahi hihia, paipai mākou e lawe i ka Spermidine i ka wā ʻai e hoʻonui ai i ka bioavailability.
Hiki iaʻu ke lawe i ka spermidine i ka wā hoʻokēʻai?
Hōʻike nā haʻawina e hoʻonui pono i ka spermidine supplements i ka autophagy. He ala ikaika ka Spermidine e hoʻokēʻai ai i nā lā ke makemake ʻoe e ʻai a i ʻole e hoʻonui i kāu wikiwiki intermittent no nā pōmaikaʻi hou aʻe (no wau iho, hoʻohana wau i ka hoʻokē ʻai a me ka spermidine supplements i hana ʻia me ka pauka spermidine trihydrochloride e mālama ai i ka autophagy).
He aha ka Spermidine 3HCL?
ʻO Spermidine kahi polyamine aliphatic kūlohelohe i hana ʻia i loko o ke kino kanaka, a me kekahi mau meaʻai. Ua hoʻokaʻawale mua ʻia nā meaʻai Spermidine mai ka semen, no laila ka inoa, akā i kēia manawa ua hana ʻia me ka synthetically a lawe ʻia mai nā meaʻai. Hāʻawi ʻo Phcoker i ka pauka spermidine trihydrochloride nui me ke kumukūʻai kūʻai nui. Loaʻa iā mākou ka pauka spermidine trihydrochloride kiʻekiʻe no ke kūʻai aku.
He aha ka Autophagy?
Hana ʻo Autophagy e like me kahi polokalamu hoʻoheheʻe ʻōpala. Hiki ke kōkua i kāu mau cell e hoʻomaʻemaʻe i nā protein i hōʻino ʻia a i ʻole i hoʻopili hewa ʻia a me nā organelles nui e hiki ai ke alakaʻi i ka maʻi pili makahiki, a hoʻololi hou iā lākou i loko o nā ʻāpana kelepona hana, e hopena i ka hoʻōla hou ʻana o ke kelepona. Ma nā ʻano he nui e waiho ai ʻo autophagy i ke kumu no ke ola kelepona lōʻihi a olakino. I ko mākou mau makahiki, hoʻomaka ka autophagy e lohi a ma hope o ka stagnates, e hoʻonui iā mākou i ka maʻi. Eia naʻe, hiki iā mākou ke hoʻoikaika i ka autophagy ma o ka hoʻokē ʻai a i ʻole nā mea hoʻohui Spermidine.
Pehea e hoʻonui ai i ka pae spermidine i loko o kou kino?
ʻO ka mea pōʻino, hōʻiliʻili ko mākou kino i ka pōʻino i ko mākou mau makahiki, e hoʻonui ana i ko mākou makemake i ka maʻi. Pēlā nō, e emi mālie ana kā mākou mau spermidine kūlohelohe me ka makahiki. Eia naʻe, hiki ke hoʻoponopono ʻia kēia ma ka ʻai ʻana i nā meaʻai kiʻekiʻe i ka spermidine a me ka lawe ʻana i nā mea hoʻohui Spermidine, no laila e kaupalena ʻia ka hopena o ka ʻelemakule i ka lōʻihi o ke ola. ʻOiai ʻoi aku ka maikaʻi o ka ʻai ʻana i nā meaʻai like ʻole i waiwai nui i nā meaʻai holoʻokoʻa, ʻo ke ala maikaʻi loa e hoʻemi ai i ka emi ʻana o nā pae spermidine ma ka lawe ʻana i ka pauka spermidine trihydrochloride. ʻOiai ʻaʻole mālama ʻia e ka FDA me ka maʻamau like me nā lāʻau lapaʻau, loaʻa nā mea hoʻohui lōʻihi i nā mea i ʻike maoli ʻia i loko o ke kino a me ka meaʻai, no laila e hoʻohui i ka hopena kiʻekiʻe me ka haʻahaʻa haʻahaʻa. Loaʻa nā mea hoʻohui Spermidine ma ka pauka a i ʻole ka papa papa a ke lawe mau ʻia hiki ke hoʻopaneʻe maikaʻi i ka makahiki. ʻO kahi kumuhana wela e pili ana i ka hiʻohiʻona hoʻohui lōʻihi, aia kekahi mau hōʻailona hoʻokūkū o nā mea hoʻohui spermidine i kūʻai ʻia ma ke ʻano he mau pono anti-aging. Hoʻolālā ʻia e lawe ʻia i kēlā me kēia lā e kākoʻo i ke ola olakino, hiki ke hoʻohui pū ʻia nā mea hoʻohui me nā mea lōʻihi e like me Resveratrol. ʻO nā mea hoʻohui Spermidine maikaʻi loa ka mea i hana ʻia me ka pauka spermidine trihydrochloride. ʻOi aku ka paʻa o ka pauka Spermidine trihydrochloride, kūʻai mau i ka pauka spermidine trihydrochloride mai nā mea kūʻai maoli.
ʻO Spermidine kahi mea hou ma ka mākeke hoʻohui no ka anti-aging a me ka lōʻihi. Hiki ke kiʻi ʻia ka pauka spermidine extract mai ka Wheat Germ, akā ʻoi loa ka haʻahaʻa o ka spermidine i loko, ʻoi aku paha ma mua o 0.1% i ka maʻemaʻe.
He aha ka Spermidine?
ʻO Spermidine kahi pūhui polyamine i loaʻa maʻamau i loko o nā ribosomes a me nā ʻiʻo ola i loaʻa nā hana metabolic like ʻole i loko o nā mea ola a he hana koʻikoʻi i ka hana cell a me ke ola. Ke noʻonoʻo nei paha ʻoe no ke aha i kapa ʻia ai kēlā ʻano; ʻAe, ʻo ia no ka mea i ʻike mua ʻia ka pūhui i loko o kahi laʻana o ka semen i ka makahiki 1687 e ka mea hoʻomaʻamaʻa ʻo Dutch microscopist kaulana ʻo Anton Van Leeuwenhoek, no laila ka inoa. Eia naʻe, loaʻa ia i loko o nā cell eukaryotic a pau.Hoʻokumu ʻia ka Spermidine mai kona precursor, ka putrescine pūhui i loko o ke kino. ʻO Putrescine ka mea mua no ka spermine, kekahi polyamine i mea nui no ka hana kelepona. ʻO ka putrescine a me ka spermidine ke kōkua i ka ulu a me ka hana o ke kino. Pehea? Hiki i nā polyamines ke hoʻopaʻa i nā molekole like ʻole, a ma laila lākou e hoʻoikaika ai i ka ulu ʻana o ka cell, ke kūpaʻa DNA, ka hoʻonui ʻana o ka cell, a me nā kaʻina apoptosis. ʻIke ʻia hoʻi ka hana like ʻana o nā polyamines me nā mea ulu i ka wā o ka māhele cell.
Spermidine a me autophagy
Ma mua o ko mākou luʻu ʻana i kekahi o nā noiʻi hoihoi ma hope o ka spermidine a no ke aha i manaʻo ai kekahi poʻe noiʻi he mea pono ia i ka hoʻolohi ʻana i ka ʻelemakule, pono mākou e nānā mua i ke ʻano o ka hana ʻana.E like me kā mākou e ʻike ai, hiki i ka putrescine ke hana i ka spermidine ma ke ʻano he kaʻina hana e wāwahi ai ka putrescine i ka decarboxylated S-adenosylmethionine.
He kuleana koʻikoʻi ia i ka hoʻoponopono ʻana i nā kaʻina hana olaola like ʻole, me nā pae o ka pH intracellular a me ka mālama ʻana i ka hiki o ka membrane cell. He kuleana koʻikoʻi ka Spermidine i kekahi mau kaʻina hana koʻikoʻi koʻikoʻi, me nā mea hoʻokipa aspartate, cGMP/PKG alahele hoʻāla, nitric oxide synthase, a me ka hana cerebral cortex synaptosome.
He mea hoihoi ka Spermidine i ka poʻe ʻepekema i ka pōʻaiapili o ka ʻelemakule no ka mea ʻo ia kahi mea hoʻoholo morphogenetic koʻikoʻi no ke ola o nā cell a me nā ʻiʻo ola [3].
ʻO ka hiki i ka spermidine ke hoʻoulu i ka autophagy i manaʻo ʻia ʻo ia ke kumu nui e ʻike ʻia e hoʻolōʻihi i ka ʻelemakule a kākoʻo i ka lōʻihi [4].
Ua hōʻike ʻia i ka hoʻoulu ʻana i ka autophagy i loko o nā ʻiole ate, nā ilo, ka hū a me nā lele [5].
ʻO kahi mīkini autophagy kīnā ʻole a me ka nele o ka spermidine e hoʻopili nui ʻia me ka emi ʻana o ke ola, ke koʻikoʻi mau, a me ka ʻeha nui.
Nā ʻano spermidine a me nā kikoʻī
ʻO nā huaʻōlelo ʻē aʻe e pili ana i ka spermidine he spermidine trihydrochloride pauka, Wheat Germ Extract Powder (Spermidine) 1%.He aha ka Spermidine trihydrochloride pauka?
ʻO Spermidine trihydrochloride pauka, ʻo ia ke ʻano trihydrochloride o spermidine. Aia ka waihona Spermidine ma ke ʻano wai, ʻoiai ʻo Spermidine trihydrochloride ma ke ʻano pauka. ʻO Spermidine trihydrochloride kahi ʻano kūpaʻa ʻoi aku ka paʻa o ka spermidine. ʻO Spermidine trihydrochloride powder benfits like me nā pono Spermidine.
He aha ka Wheat Germ Extract 1%?
Loa'a ka nui o ka Spermidine i loko o ka hua hua hua hua, he 1% ka spermidine. He mea pono ka Spermidine i loko o ka hua palaoa i ka lohi i ka ulu ʻana o ka maʻi kanesa a hoʻonui i ke olakino cardiovascular. Loaʻa iā ia nā antioxidants a hiki ke hoʻomaikaʻi i kou palekana holoʻokoʻa.
Pehea e hana ai ka spermidine
ʻO Spermidine ka mea ʻawaʻawa ʻole. ʻO Spermidine kahi polyamine kūlohelohe e hoʻoulu ai i ka autophagy cytoprotective. ʻO ka mea e hana ai i ka spermidine mea kūikawā kona hopena o ka hoʻolaha ʻana i ke kaʻina kūlohelohe o autophagy i loko o ke kino, ka mea e mālama ai i nā cell hou a olakino.Hana ʻo Autophagy ma ke ʻano he lawelawe hoʻolei ʻōpala kelepona. Kōkua kēia polokalamu hoʻomaʻemaʻe ponoʻī i nā cell ma o ka wehe ʻana i nā mea āpau mai nā protein i hōʻino ʻia a i ʻole i hoʻopili hewa ʻia i nā organelles holoʻokoʻa a laila hana hou iā lākou. He kuleana koʻikoʻi kēia no ka mea ua hoʻopilikia maikaʻi ʻia nā mea kelepona i hōʻino ʻia i ke olakino cell a i nā hihia koʻikoʻi hiki ke hōʻeha nui.
Mālama pū ʻo ia i kāu mau cell mai nā pūhui ʻino e like me nā radical manuahi. Loaʻa i ka Spermidine nā waiwai anti-kahiko no ka mea e hoʻonui ai i ka hoʻoikaika kino i loko o kou kino. No ka laʻana, hoʻomaikaʻi ia i ke olakino o ka puʻuwai a me ka lolo, e hoʻohaʻahaʻa i ka hiki ʻana o nā maʻi pili makahiki. Hiki iā ʻoe ke hoʻonui i ka pae Spermidine āu e lawe ai i kēlā me kēia lā ma ka lawe ʻana a kūʻai aku i ka pauka hoʻohui Spermidine.
Nā kumu spermidine(He aha nā meaʻai i kiʻekiʻe i ka spermidine)
Loaʻa ka Spermidine i kēlā me kēia cell o ke kino. ʻAʻole hana maoli ʻia ka huahana kūlohelohe e nā cell ponoʻī, akā na kekahi enterobacteria. Ma kahi o hoʻokahi hapakolu o ka spermidine e hana ʻia i loko o ke kino aʻo ke koena ʻelua hapakolu, ka hapa nui, e lawe ʻia mai kā mākou meaʻai.Hiki ke hoʻoheheʻe ʻia ka Spermidine i ka wai, ʻo ka holoi ʻana i ka wai e hōʻemi nui i ka spermidine i ka meaʻai.
Laulaha:
He haʻahaʻa ka hua i loko o ka spermidine, ʻo ka mea lanakila he mango me ka 3 mg/100g ʻiʻo a me ka iʻa he haʻahaʻa i ka spermidine, ʻo ka mea lanakila he pipi minced me 4mg/100g nati a me nā hua maloʻo he haʻahaʻa i ka spermidine: ʻo ka mea lanakila he hazelnuts me 2mg/100g. He haʻahaʻa nā huaʻai i ka spermidine, ʻo ka mea lanakila ka kulina me 3mg/100g
24.3 mg/100g hua huapalaoa
19 mg / 100g cheese cheddar
6 - 14 mg/100g pī
19 mg/100g ʻulaʻula
2- 10 mg/100g broccoli a me ka pua pua
9 mg/100g Champignons de Paris nā haloo
3 mg/100g mango
3 mg/100g moa
3 mg/100g kulina
2 mg/100g celery a me ka melon
2 mg/100g palaoa palaoa
ʻOiai e loaʻa ana ka spermidine i nā meaʻai holoʻokoʻa, hiki ke lawe ʻia ma ke ʻano hoʻohui - ke ala maikaʻi loa e mālama ai i kāu mau spermidine pae. Nui nā mea hoʻohui spermidine no ke kūʻai aku ma ka pūnaewele, e kiʻi i nā hopena maikaʻi loa, kūʻai i ka huahana mai ka mea hoʻolako Spermidine kūpono.
Loaʻa i nā mea hoʻohui Spermidine ka maikaʻi o ka loaʻa ʻana o ka nui o ka mea hana. ʻO nā kumu kūlohelohe, ma ka ʻaoʻao ʻē aʻe, aia i ka nui o nā ʻano kūlohelohe. No laila, ʻo ka pauka spermidine trihydrochloride kiʻekiʻe kāu koho maikaʻi loa inā makemake ʻoe e uku pono i ka emi ʻana o ka spermidine pili makahiki.
Nā pōmaikaʻi o Spermidine
ʻO Spermidine anti-agingHana ʻia ka ʻelemakule o ke kelepona i ka wā e hewa ai ke kaʻina hana maoli o autophagy, ʻo ia hoʻi ka hana hou ʻana o nā cell i pōʻino. ʻO Spermidine, ma ke ʻano he autophagy modulator, hiki ke lilo i mea kaua kūpono e kūʻē i ka ʻelemakule. E emi ana ka nui o ka spermidine me ka makahiki. ʻO ka lawe ʻana i ka pauka spermidine supplement e pili ana i ka ʻelemakule a hoʻemi i ka helu o nā radical manuahi.
Ka ulu ʻana o ka spermidine a me ka lauoho
Ua hōʻike ka noiʻi ʻana i ka hoʻohana ʻana i nā mea hoʻohui spermidine hiki ke hoʻoikaika i ka ulu lauoho. No ka laʻana, ua hōʻike ʻia kahi noiʻi o 100 mau kānaka olakino e hoʻolōʻihi i ka manawa o ka ulu ʻana o ka lauoho i kapa ʻia ʻo ka anagen phase. ʻOi aku ka lōʻihi o ka noho ʻana o ka lauoho lauoho i ka manawa anagen, ʻoi aku ka lōʻihi o ka ulu ʻana o ka lauoho. Ua hōʻike pū ʻia ka noiʻi ʻana i nā paipu hoʻāʻo i ka spermidine e hoʻoulu i ka ulu lauoho kanaka.
Hoʻomaikaʻi ʻo Spermidine i ke olakino Cardiovascular
Ua hōʻike ʻia ʻo Spermidine mai nā kumu meaʻai e lawe mai i nā hopena cardioprotective ma o autophagy, e like me nā haʻawina i nā ʻiole, nā ʻiole, a me nā kānaka e hōʻike ana i ka emi ʻana o ka hypertension a me ka ʻelemakule arterial. Pēlā nō, pili ka hoʻonui ʻia ʻana o ka spermidine me ka emi ʻana o ke koko a me ka liʻiliʻi o ka maʻi cardiovascular, e alakaʻi ana i ka make haʻahaʻa o ke kanaka.
Pono ka Spermidine no ka pale ʻana i ka maʻi kanesa
Ma waho aʻe o ka hoʻonui ʻana i ke ola, a hiki i ka 25%, ua hōʻike ʻia ka noiʻi ʻana i nā ʻiole i ka hoʻemi ʻana o ka spermidine supplementation i ka fibrosis ate a me ka maʻi kanesa, ʻoiai i nā kumuhana i ʻike ʻia i nā kemika e hoʻoulu ai i ka fibrosis ate. Hoʻopili pū nā haʻawina nānā kanaka i ka ʻai ʻana o ka spermidine meaʻai me ka emi ʻana o ka pilikia o ka maʻi maʻi ʻaʻai. Ke lawe ʻoe i nā mea hoʻohui Spermidine i hana ʻia me ka pauka spermidine trihydrochloride, e hele lōʻihi ana ʻoe i ka pale ʻana i kou kino mai ka maʻi kanesa. Hiki iā ʻoe ke hoʻohana i nā mea hoʻohui Spermidine i ka wā o ka mālama ʻana i ka maʻi kanesa.
Hiki i ka Spermidine ke ho'ēmi i ka emiʻana o ka naʻau
ʻO ka noiʻi i paʻi ʻia ma 2021 i loko o ka puke moʻolelo ʻo Cell Reports e hāʻawi i kahi moʻolelo kikoʻī o ka spermidine meaʻai e hoʻomaikaʻi ai i ka cognition a me ka hana mitochondrial i nā nalo a me nā ʻiole, me kekahi mau ʻikepili kanaka e hiki mai ana i luna [13]. ʻOiai he mea hoihoi kēia haʻawina, loaʻa iā ia kekahi mau palena, a pono nā ʻikepili pane hou aku ma mua o ka hiki ke hana ʻia kahi hopena paʻa e pili ana i nā pōmaikaʻi i ka ʻike kanaka. ʻO ka lawe ʻana i ka pauka spermidine supplement hiki ke hoʻohuli i nā pōʻino neuron i kumu ʻia e ka mumū, ke kaumaha oxidative, a me ka ischemia.
Spermidine a me ke kaumaha
ʻOiai he mea nui ka spermidine i ka hoʻokumu ʻana i nā mea momona, ʻaʻohe meaʻai (a i ʻole nā mea hoʻohui) i loaʻa i kēia mea e hoʻoikaika i ke kaumaha. Pēlā nō, ʻaʻole hiki i kekahi ke ʻōlelo inā hoʻonui kēia mea i ka metabolism. Loaʻa ka noiʻi kanaka e pili ana i ka pohō kaumaha a me ka helu metabolic.
ʻO Spermidine vs NMN
ʻO lāua nā mea wela no ka anti-aging a me ka lōʻihi, akā ʻokoʻa ke ʻano o ka hana. Kōkua nā mea spermidine i ka ʻelemakule ma o autophagy, ʻoiai ʻo ka pauka NMN hiki ke loaʻa nā hopena maikaʻi i ka anti-aging ma o ka hoʻonui ʻana i nā pae NAD + i ko mākou kino. ʻO ka hoʻohui ʻana o Spermidine kahi ala maikaʻi loa e hoʻokō ai i kāu mau pahuhopu no ka mea ʻo ka autophagy kahi hana kūlohelohe e hoʻomaka ai e wāwahi a hoʻihoʻi hou i nā cell i poino.Hiki ke hoʻoheheʻe ʻia a paʻa i ka wai, me ka bioavailability kiʻekiʻe.
ʻO Spermidine vs Spermine
ʻO Spermine kekahi ʻano polyamine. Pili nā pūhui ʻelua i kekahi i kekahi. Loaʻa ka Spermine mai Spermidine a he mea koʻikoʻi ia no ka metabolism cell i loko o ke kanaka a me nā mea kanu. ʻO ka lawe ʻana i nā mea hoʻohui spermidine i hana ʻia me ka pauka spermidine trihydrochloride e hōʻoiaʻiʻo e loaʻa iā ʻoe nā pono spermine.ʻO Spermidine a me ka Mitochondria
ʻO ka mitochondria i kapa pinepine ʻia ʻo ka hale mana o ke kelepona kahi wahi kaulana loa o ka noiʻi anti-aging. Manaʻo ʻia nā hemahema i ka mitochondria e kōkua i ka ʻelemakule. Manaʻo ʻia ʻo Spermidine e hāpai i ka hoʻokumu ʻana o ka mitochondria i loko o nā cell. Eia hou, pono ka ʻikepili pane-dose ma mua o ka hiki ke hoʻoholo paʻa e pili ana i nā pono e hoʻomaikaʻi ai i ka hana mitochondria.Nā hopena ʻaoʻao o Spermidine
ʻAʻole ʻike ʻia nā hopena ʻaoʻao i ka wā e lawe ana i ka pauka spermidine supplement, inā ʻike ʻoe i nā hopena ʻaoʻao Spermidine, e hoʻōki koke i ka lawe ʻana a nīnau i kāu kauka. No ke kūʻai ʻana i ka spermidine maikaʻi loa e kōkua i ka pale ʻana i nā hopena ʻinoʻO ke ʻano o ka spermidine
ʻAʻole i hoʻokumu ʻia ka dosage spermidine maikaʻi loa, ʻoiai ʻo kekahi mau hoʻokolohua i nā poʻe ʻelemakule e hōʻike ana he palekana loa ka 1.2 mg o ka spermidine i kēlā me kēia lā.Spermidine a me COVID-19
ʻO ka mea nui i ka nūhou olakino i nā makahiki i hala iho nei, ʻo ia ka maʻi maʻi COVID-19, ka mea i loaʻa i nā hopena koʻikoʻi no ka lōʻihi, ke olakino a me ka maikaʻi o ka honua. ʻO ka hoʻohana ʻana i nā mea hoʻohui e hoʻomaikaʻi ai i ka hana immune a hōʻemi i ka mumū i lilo i mea kaulana i ka wā o ka maʻi maʻi i ka wā i lawe ai ka poʻe i ka mana kūʻokoʻa ma luna o ko lākou olakino. Hiki i nā mea hoʻohui ke kōkua i ka pale a hōʻemi i nā hōʻailona o nā maʻi hanu e like me ke anu a me ka maʻi maʻi. ʻO ka manaʻolana e hiki ke hoʻololi ʻia kēia i ka maʻi COVID-19. Ke noʻonoʻo nei ʻo kahi hana nui i hoʻopili ʻia e ka spermidine he autophagy, ʻo ia kahi ʻāpana o ka ʻōnaehana pale e hoʻomaʻemaʻe i nā pathogens a me ka hoʻoponopono ʻana i ka mumū, ʻaʻole i mamao loa kēia kuhiakau.ʻOi aku ka nui aʻe, kahi noiʻi o kēia manawa e nā virologists ma Berliner Charité e ʻimi nei i ka hiki o ka spermidine e pili ana i ke kumuhana nui o COVID-19. Ua ʻike mākou mai ka noiʻi mua ʻana e hoʻololi ka coronavirus i ka metabolism cell holoʻokoʻa, ka hopena i ka emi ʻana o nā pae spermidine, ma waena o nā hopena ʻē aʻe. ʻO kēia ka mea e pale ai i ke kaʻina o ka hoʻolei ʻana i ka ʻōpala kelepona (autophagy). Ma ka noiʻi Kelemania i ʻōlelo ʻia ma luna, ua mālama ʻia nā cell i loaʻa i ka coronavirus me ka spermidine, me ka hopena o ka hoʻonui ʻana o ka maʻi maʻi ma kahi o 85%. Ua hōʻike pū ʻia kahi noiʻi mua a Professor Simon o Oxford e hoʻoikaika ka spermidine i nā pane antiviral o ka ʻōnaehana pale. No laila he ʻelua aces i ka spermidine i ka wā e hakakā ai i ka coronavirus: (a) kaohi ʻana i ka hoʻolaha ʻana o ka maʻi virus a (b) hoʻoikaika i ka pane antiviral immune. Akā, pono mākou e kali a ʻike - e koi ʻia nā noiʻi kikoʻī kikoʻī ma mua o ka hiki iā mākou ke huki i nā hopena paʻa.
Ma hea e kūʻai ai i ka spermidine nui?
Inā paʻakikī ʻoe e lawa i kāu ʻai, hiki iā ʻoe ke loaʻa iā ia ma ke ʻano he spermidine supplements. ʻO ka spermidine synthetic i hoʻohana ʻia i nā mea hoʻohui e like me ka mole kūlohelohe maoli.E ʻike nui ʻoe i ka palaoa germ extract spermidine powder capsules ke hoʻāʻo ʻoe e ʻimi i nā mea hoʻohui spermidine - akā ʻaʻole maʻamau kēia mau mea. ʻAʻole helu ka hapa nui i ka nui o ka spermidine iā lākou. Hāʻawi ʻo Phcoker i ka pauka spermidine trihydrochloride nui. ʻO ka pauka spermidine supplement maikaʻi loa me ka maʻemaʻe kiʻekiʻe a me ka bioavailability.
ʻO kā mākou hui ma ke ʻano he hale hana hana e hāʻawi i nā kumukūʻai nui a me nā kumukūʻai kūʻai nui e pili ana i ka pauka spermidine trihydrochloride a me Spermidine.
FAQs
Ua like anei ka spermidine me ka hua palaoa?Loaʻa ka Spermidine i ka nui o nā meaʻai a mākou e ʻai ai. A ʻo ka mea ʻoiaʻiʻo, ʻo kā mākou Wheat Germ Extract Powder (Spermidine) 1% i lawe ʻia mai ka hua palaoa. Eia nō naʻe, ʻaʻole loaʻa pinepine iā mākou ka mea e pono ai mākou mai ka meaʻai wale nō, ʻoi aku ka nui o ko mākou mau makahiki a makemake nui ko mākou kino i nā meaʻai. ʻO kēia kahi e hiki ai i nā mea hoʻohui ke komo i ke kākoʻo i ke kino olakino.
He palekana anei ka lawe ʻana i ka spermidine?
ʻAe, he huahana kūlohelohe ia i loko o ke kino a he ʻāpana o kā mākou meaʻai kūlohelohe. Hōʻike ka ʻikepili i ka hoʻohui ʻana i ka spermidine me ka hoʻohana ʻana i ka pauka spermidine trihydrochloride ka palekana a me ka ʻae maikaʻi.
Hoʻopau anei ke kuke i ka spermidine?
I ka hihia o kekahi mau hana kuke e pili ana i nā wela kiʻekiʻe (53) i wehewehe ʻia ʻo ka ʻala ʻana, ka ʻai ʻana, a i ʻole ka palai ʻana i hana i nā poho a hiki i ka 60% o ka spermidine a me ka spermine i loko o ka ʻiʻo moa.
I ka manawa hea wau e lawe ai i nā mea hoʻohui spermidine?
Ua hōʻike ʻia kekahi mau hoʻokolohua he palekana loa ka 1.2 mg o spermidine i kēlā me kēia lā. Inā hana ʻia kēia i ke kakahiaka, i ke awakea a i ke ahiahi paha, e pili ana i kāu makemake pilikino, akā paipai mākou e lawe mau i ka manawa like o ka lā.
He spermidine anei ka sperm?
Ua ʻike mua ʻia ʻo Spermidine i loko o kahi laʻana o ka semen i ka makahiki 1687 e ka microscopist Dutch kaulana ʻo Anton Van Leeuwenhoek, no laila ka inoa. Eia naʻe, loaʻa ia i loko o nā cell eukaryotic a pau. Aia ka Spermidine ma lalo o ka Semen.
Pono au e lawe i nā mea hoʻohui spermidine?
Hōʻike nā haʻawina mua e hiki ke kōkua i ka ʻai waiwai nui o ka spermidine i ke ola lōʻihi. ʻO ka lawe ʻana i nā mea hoʻohui spermidine i kēlā me kēia lā i kou mau makahiki he ala palekana ia e pale aku ai i nā maʻi pili i ka makahiki a hāpai i ke olakino holoʻokoʻa.
Hiki i ka spermidine ke hoʻihoʻi i ka wā kahiko?
Hiki i ka lako waho o ka polyamine spermidine maoli ke hoʻolōʻihi i ke ola o nā mea hoʻohālike e like me ka hū, nā nematodes, nā nalo a me nā ʻiole. Hōʻike nā hōʻike epidemiological hou i ka hoʻonui ʻia ʻana o ka spermidine me ka meaʻai e hōʻemi ana i ka nui, ka maʻi cardiovascular a me ka maʻi kanesa pili i ke kanaka.
ʻEhia ka nui o ka spermidine i loko o ka paʻakai kahiko?
ʻOi aku ka nui o ka paʻakai, ʻoi aku ka nui o nā polyamines i loko.
ʻO Spermidine ka mea like. Loaʻa i ka paʻakai makua ka awelika o 10 mg o spermidine no 100 g o ka meaʻai, e like me nā loiloi 2011. No laila ke hōʻoia nei nā kānaka ʻepekema mai Graz i ka paʻakai paʻa i ka hopena maikaʻi no ka puʻuwai, akā kuhikuhi pū kekahi i ka momona momona.
Hiki iaʻu ke lawe i ka spermidine ma ka ʻōpū ʻole?
I kekahi hihia, paipai mākou e lawe i ka Spermidine i ka wā ʻai e hoʻonui ai i ka bioavailability.
Hiki iaʻu ke lawe i ka spermidine i ka wā hoʻokēʻai?
Hōʻike nā haʻawina e hoʻonui pono i ka spermidine supplements i ka autophagy. He ala ikaika ka Spermidine e hoʻokēʻai ai i nā lā ke makemake ʻoe e ʻai a i ʻole e hoʻonui i kāu wikiwiki intermittent no nā pōmaikaʻi hou aʻe (no wau iho, hoʻohana wau i ka hoʻokē ʻai a me ka spermidine supplements i hana ʻia me ka pauka spermidine trihydrochloride e mālama ai i ka autophagy).
He aha ka Spermidine 3HCL?
ʻO Spermidine kahi polyamine aliphatic kūlohelohe i hana ʻia i loko o ke kino kanaka, a me kekahi mau meaʻai. Ua hoʻokaʻawale mua ʻia nā meaʻai Spermidine mai ka semen, no laila ka inoa, akā i kēia manawa ua hana ʻia me ka synthetically a lawe ʻia mai nā meaʻai. Hāʻawi ʻo Phcoker i ka pauka spermidine trihydrochloride nui me ke kumukūʻai kūʻai nui. Loaʻa iā mākou ka pauka spermidine trihydrochloride kiʻekiʻe no ke kūʻai aku.
He aha ka Autophagy?
Hana ʻo Autophagy e like me kahi polokalamu hoʻoheheʻe ʻōpala. Hiki ke kōkua i kāu mau cell e hoʻomaʻemaʻe i nā protein i hōʻino ʻia a i ʻole i hoʻopili hewa ʻia a me nā organelles nui e hiki ai ke alakaʻi i ka maʻi pili makahiki, a hoʻololi hou iā lākou i loko o nā ʻāpana kelepona hana, e hopena i ka hoʻōla hou ʻana o ke kelepona. Ma nā ʻano he nui e waiho ai ʻo autophagy i ke kumu no ke ola kelepona lōʻihi a olakino. I ko mākou mau makahiki, hoʻomaka ka autophagy e lohi a ma hope o ka stagnates, e hoʻonui iā mākou i ka maʻi. Eia naʻe, hiki iā mākou ke hoʻoikaika i ka autophagy ma o ka hoʻokē ʻai a i ʻole nā mea hoʻohui Spermidine.
Pehea e hoʻonui ai i ka pae spermidine i loko o kou kino?
ʻO ka mea pōʻino, hōʻiliʻili ko mākou kino i ka pōʻino i ko mākou mau makahiki, e hoʻonui ana i ko mākou makemake i ka maʻi. Pēlā nō, e emi mālie ana kā mākou mau spermidine kūlohelohe me ka makahiki. Eia naʻe, hiki ke hoʻoponopono ʻia kēia ma ka ʻai ʻana i nā meaʻai kiʻekiʻe i ka spermidine a me ka lawe ʻana i nā mea hoʻohui Spermidine, no laila e kaupalena ʻia ka hopena o ka ʻelemakule i ka lōʻihi o ke ola. ʻOiai ʻoi aku ka maikaʻi o ka ʻai ʻana i nā meaʻai like ʻole i waiwai nui i nā meaʻai holoʻokoʻa, ʻo ke ala maikaʻi loa e hoʻemi ai i ka emi ʻana o nā pae spermidine ma ka lawe ʻana i ka pauka spermidine trihydrochloride. ʻOiai ʻaʻole mālama ʻia e ka FDA me ka maʻamau like me nā lāʻau lapaʻau, loaʻa nā mea hoʻohui lōʻihi i nā mea i ʻike maoli ʻia i loko o ke kino a me ka meaʻai, no laila e hoʻohui i ka hopena kiʻekiʻe me ka haʻahaʻa haʻahaʻa. Loaʻa nā mea hoʻohui Spermidine ma ka pauka a i ʻole ka papa papa a ke lawe mau ʻia hiki ke hoʻopaneʻe maikaʻi i ka makahiki. ʻO kahi kumuhana wela e pili ana i ka hiʻohiʻona hoʻohui lōʻihi, aia kekahi mau hōʻailona hoʻokūkū o nā mea hoʻohui spermidine i kūʻai ʻia ma ke ʻano he mau pono anti-aging. Hoʻolālā ʻia e lawe ʻia i kēlā me kēia lā e kākoʻo i ke ola olakino, hiki ke hoʻohui pū ʻia nā mea hoʻohui me nā mea lōʻihi e like me Resveratrol. ʻO nā mea hoʻohui Spermidine maikaʻi loa ka mea i hana ʻia me ka pauka spermidine trihydrochloride. ʻOi aku ka paʻa o ka pauka Spermidine trihydrochloride, kūʻai mau i ka pauka spermidine trihydrochloride mai nā mea kūʻai maoli.
Reference:
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- He mea kākau like ʻo Ghada Alsaleh, ʻo Isabel Panse, Leo Swadling, Hanlin Zhang, Felix Clemens Richter, Alain Meyer, Janet Lord, Eleanor Barnes, Paul Klenerman, Christopher Green, Anna Katharina Simon. "Hoʻomau ʻia ʻo Autophagy i nā cell T mai nā mea hāʻawi kahiko e ka spermidine a hoʻopili ʻia me ka hana a me nā pane kano" Dec 15, 2020.
- Hōʻike ka loiloi o SARS-CoV-2-controlled autophagy i ka spermidine, MK-2206, a me ka niclosamide ma ke ʻano he putative antiviral therapeutics. Nils C. Gassen, Jan Papies, Thomas Bajaj, Frederik Dethloff, Jackson Emanuel, Katja Weckmann, Daniel E. Heinz, Nicolas Heinemann, Martina Lennarz, Anja Richter, Daniela Niemeyer, Victor M. Corman, Patrick Giavalisco, Christian Drosten, Marcel A .Müller. doi: 10.1038/s41467-021-24007-w
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