1. He aha ka Pterostilbene?

ʻO Pterostilbene kahi lāʻau kūlohelohe kūpono i hana ʻia ma ke ola o kekahi mau mea kanu ma ke ʻano o ke kaua ʻana i nā maʻi. Hoʻohālikelike kēia pūlehu me kahi pūnaehana ʻike ʻia i kapa ʻia ʻo resveratrol a maʻalahi i ka loaʻa i kahi palapala hoʻohui. Pākuʻi nui ʻo Pterostilbene. ʻO kēia keʻaʻa hiki iā lākou ke komo maʻalahi i loko o ke kino a me ka wikiwiki a paʻa ʻole i ke kaʻina hana. ʻO ka pulupulu Pterostilbene he maikaʻi, akā naʻe ka pōkole o kona hapalua ma lalo o 100 mau minuke.

Nā kumuwaiwai Pterostilbene

Pterostilbene nā kumu meaʻai e hoʻohana ai nā blueberries, almonds, cranberry, mulberry, mani, red red wine, red grapes, grape leaf, India kino tree bark, Red sandalwood, and cocoa. ʻO nā Blueberries, ʻo ke kumu kiʻekiʻe o ka meaʻai Pterostilbene, akā liʻiliʻi ka nui o nā blueberries i hoʻohālikelike ʻia i nā koina Pterostilbene. Kuhi ʻia ka ʻōlelo Pterostilbene blueberries ma kahi o 99 a 52 mau nanograms, ma kēlā me kēia pā o nā blueberries.

pterostilbene-pauku

2.Nā hana Pterostilbene o ka hana

ʻOkoʻa ka hana pterostilbene hana i ka resveratrol. ʻO ka pterostilbene pūnaʻi ka nui o ka stilbene. ʻO nā pono Pterostilbene pauka ʻē aʻe e pili ana i ka ʻenehana like ʻole o ka hana a. ʻO ka hana lāʻau lapaʻau o ka trans-pterostilbene e pili ana i ka antineoplastic, antioxidant, a me ka anti-inflammatory.

Hōʻike ka Pterostilbene i nā hana antifungal mehana he ʻumi mau manawa ma mua o ka resveratrol. Hōʻike pū ka waihona ʻoterterilbene i nā hopena antiviral. ʻO ka pale o nā mea kanu mai nā pathogens e like me ke ʻano he mana nui o nā stilbenes, me ka Pterostilbene, a me kēia mau hana i nā holoholona a me nā kānaka pū kekahi.

Hōʻike pū ʻo Pterostilbene i nā hopena anticancer ma o kekahi mau mea molekole. Hōʻike nā hōʻike noiʻi i nā hana Pterostilbene me nā gen suppressor gen, ke hoʻololi ʻana i nā ala poloka transduction, oncogenes, nā ʻōnaehana hoʻoliʻi selela, a me nā huaʻelima hoʻoponopono lula.

ʻOkoʻa nā mea Antioxidative o Pterostilbene mai ka resveratrol. Ma resveratrol, hōʻuluʻulu nā ʻekolu o ka hui hydroxyl i ROS (reactive oxygen species) i ka lymphoblasts kaʻawale a me ke koko a pau ʻo Pterostilbene, nona ka hui 1 hydroxyl a me 2 mau hui methoxy e hoʻoneʻe i ka ROS extracellular. ʻO ke kaona ʻana o nā waiwai antioxidation e hiki ai i ka hoʻohana ʻana o ka pauka Pterostilbene e kau i ka extracellular reactive oxygen species, ka mea e hōʻeha ai i ka iwi i ka wā o ka hana aʻeha.

Ma lalo aʻe nei he mau ʻano hana pterostilbene o ka hana i kūkākūkā ʻia ma nā kikoʻī;

Hoʻolaha ka hana Pterostilbene; Hoʻokomo ʻia ʻo Sirtuin

Hoʻohui ka Pterostilbene i kahi ala hōʻailona SIRT1 i loko o nā pona e hāʻawi ai i ka pale i ka hōʻino o ka cellular, ma laila e hoʻōla ai. Hoʻonui kēia ala i ka hōʻike p53. ʻO ka P53 ka protein ka mea e pale ai i ka DNA ma ka hōʻino a pale aku i nā pūpū i nā mutations e hiki ai i ka maʻi kanesa.

Hiki i ka SIRT1 ke pale iā ʻoe mai ka pōʻino a me ka hōʻemi o nā pūnao, e holomua ana me ka wā e ʻoi aku ana.

Nā hopena anti-inflammatory

Ua hōʻike ʻia kekahi mau noiʻi ʻo ka pterostilbene chemical compound lowers inflammation e hoʻoponopono ʻia e TNF-alpha (tumor necrosis factor-alpha). Hōʻeha ka hoʻonaninani Oxidative i nā mumū; Pterostilbene poloka interleukin-1b a me TNF-alpha ma ka hoʻohaʻahaʻa i nā ʻano oxygen react.

Mālama kēia pūlea i ka hoʻoweliweli ʻana i loko o kahi ʻāpana o ka mīkini kelepona i ʻike ʻia ʻo ka ER (endoplasmic reticulum). Ma kahi noiʻi, i ka wā i hōʻike ʻia ai ka lula o nā kihi koko i ka pauka Pterostilbene, ʻaʻole i pane o ko lākou lula i nā hōʻailona hōʻailona, ​​ʻaʻole lākou ʻike.

Hoʻolaha ka hana Pterostilbene; Nā hopena anti-cancer

ʻO ka mea kupaianaha, ʻoiai ke hoʻemi ʻana i ka kaumaha o ER (endoplasmic reticulum) i ka moʻo o nā kīʻaha koko, hoʻokūkū ʻo Pterostilbene i ke kaumaha i ka retopona endoplasmic o nā ʻoihana kanesa. No laila, pili i ka hoʻopale huna ʻana i nā ʻōnaehana maʻi a pale aku e pale i ka hoʻā ʻana i ka oxidative i loko o nā wahi olakino.

I nā pūnaʻi kōpaʻa a spinal a i ʻole (glioma), e hoʻohaʻahaʻa ka Pterostilbene Bcl-2 a hāpai i ka Bax; Hoʻonui kēia mau hoʻololi i ka hōʻailona "make" i hiki ke make nā iwi spula a i ʻole nā ​​lolo.

Hoʻohana ka nui o nā maʻi maʻi i kahi ala i ʻike ʻia ʻo Notch-1, e pale ai iā lākou iho mai ke ʻano o nā lāʻau lapaʻau, me ka oxaliplatin a me fluorouracil. Pterostilbene poloka Notch-1 hōʻailona i ka hana ʻana i nā ʻōpū i ʻoi aku i ka naʻau ma o ka chemotherapy.

ʻO ka hoʻohaʻahaʻa ka Pterostilbene i ka hoʻouluulu ʻana i nā pūhui hoʻoliʻi ulu o ka lolo, me nā MUC1, b-catenin, Sox2, NF-κB, a me CD133. Hoʻopili kēia mau hopena i ka hoʻoneʻe ʻana a hoʻōki a hiki i ka hiki ke hiki i ka nui o nā kōpili o ke kanesa.

neuroprotection

Hiki i ka Pterostilbene ke kuhikuhi i ka ʻāina hippocampus selektifly i ka lolo. Maanei, e hoʻoluhi ai i ka CREB (cAMP pane element-binding protein), BDNF (nā kumu neurotrophic-lawe ʻia mai ka lolo), a me MAPK (mologen-activated kinases protein kinases),

Hāʻawi nā mea ʻekolu i nā neurons i ka hoʻonui ʻana, e ulu ana a me ka pane maikaʻi ʻana i ko lākou wahi a puni. Hoʻokomo pū ʻia nā SNRI antidepressants i kēia mau ala.

Hoʻoulu ka Pterostilbene i ka protein i ʻike ʻia ʻo Nrf2 i loko o ka hippocampus, a ʻo ia hoʻi e hoʻopiʻi i ka hōʻike o nā protein antioxidant.

Mālama ka Pterostilbene i ke kino e kūʻē i ka maʻi ʻo Alzheimer ma o ka hāʻawi ʻana i ka palekana i ka lolo i ka beta-amyloid (Aβ). Hana ʻo ia ma o ka pili ʻana iā Akt a me PI3K, ʻelua mau protein e kākoʻo i ka ulu ʻana o ka neuron, hoʻomanaʻo, a me ke aʻo ʻana.

3. Loaʻa nā pōmaikaʻi Pterostilbene

ʻO nā kūkākūkā ma lalo nei ʻekolu mau mea nui kapula pterostilbene pōmaikaʻi;

pterostilbene-pauku-2

i. Pterostilbene as nootropics

Ke hele nei mākou, lilo ʻo ia mau hiʻohiʻona hou o ka noʻonoʻo i mea paʻakikī. ʻO ka hiki ʻole ke hana i nā hana cognitive maʻamau ke emi iho. Hiki i nā mea hoʻohui Pterostilbene ke kōkua i ka hana ʻana i kahi neural rejuvenated i kēlā me kēia makahiki.

ʻO Pterostilbene kahi nootropic ikaika, e kōkua ana i ka hoʻomaha ʻana o ka noʻonoʻo a me ka hoʻonui ʻana cognition. Lawe ʻia kekahi i ka hana o ka pre-workout ma muli o kona hiki ke kōkua i ka vasodilation o nā kīʻaha koko. No laila, hāʻawi aku i nā hopena e like me nā mea'ē aʻe o ka nitric oxide e hoʻonui ana i nā mea e pono ai.

ʻO nā pōmaikaʻi Pterostilbene nootropic e manaʻoʻiʻo ʻia ana ma muli o kona hiki ke hoʻāla i nā pae o dopamine. I nā rodents, hoʻohaʻahaʻa ka Pterostilbene i ka hopohopo a hoʻonui i ka momona. Ma kahi noiʻi e pili ana i nā rodents pakeke, nā mea hou o ka pterostilbene i hāpai i nā kiʻekiʻe o ka dopamine a me ka cognition i hoʻonui ʻia. Eia nō hoʻi, i ka wā i hoʻolako ʻia ai ka Pterostilbene i loko o nā mākino hippocampus i nā kihe, ua hoʻonui ʻia ko lākou hoʻomanaʻo hana.

Ma kahi noiʻi e pili ana i nā kiʻī, hoʻomaikaʻi hou ʻia ʻo Pterostilbene i ka nui o nā pūlei hou o ka ulu ʻana i ka hippocampus. Pēlā hoʻi i ulu aihela i nā selika i nā ʻōpio a nā keiki ʻōpio i ka wā e ʻike ʻia ai ka Pterostilbene.

Wahi a nā loiloi cell, pterostilbene powder blocks MAO-B (monoamine oxidase B) a hoʻonui i ka dopamine i loko o kā mākouole. Hoʻohā like kēia hana i nā lāʻau lapaʻau e mālama ai i ka maʻi maʻi o Parkinson, e like me ka rasagiline, safinamide, a me selegiline. Ma kahi noiʻi, mālama pū ʻo Pterostilbene i nā neurons i ka hōʻino i pili me AD (maʻi o Alzheimer).

Manaʻo nō hoʻi ka mālama ʻana i ka mana o Pterostilbene e like me ka mea i hiki ai iā ia ke pale i ka monoamine oxidase B. Ma kahi noiʻi, hōʻike ʻo Pterostilbene i ka hana anxiolytic i ʻelua a me hoʻokahi mg / kg mau wai. ʻO kēia hana anxiolytic o ka hoʻopili like ʻana me ka like o ka diazepam ma hoʻokahi a ʻelua mg / kg i ka EPM.

ii. Pterostilbene a Obesity

Ua hōʻike ʻia kahi noiʻi i ka hiki o Pterostilbene e hoʻokele i ka momona he hōʻike nui ka pilina ma waena o ka pterostilbene supplementation and weight management. Ua manaʻo ka poʻe ʻepekema ʻo Pterostilbene powder ka mea e hiki ai ke hoʻopilikia i ka nui o ka momona o ka momona ma muli o kona hiki ke hoʻēmi i ka lipogenesis. ʻO Lipogenesis ka hana e hana ai i nā nui momona momona. ʻO Pterostilbene hoʻi Hoʻoulu i ka momona a i ʻole ka momona momona i loko o ke kua.

Ma kahi noiʻi e pili ana i ka poʻe waena waena me ka cholesterol kiʻekiʻe, kahi hui o nā poʻe i lawe ʻole i nā lāʻau kolamu i mau mea momona ma ke kau ʻana ma nā kumu lāʻau pterostilbene. Ua hiki mai kēia mau hopena i mea pīhoihoi i ka poʻe noiʻi no ka mea, ʻaʻole i noi ʻia kēia noi e ana i ka hoʻomoʻo pterostilbene ma ke ʻano he kōkua kōkua kaumaha.

Hōʻike pū ʻia nā holoholona a me nā loiloi ʻo ka pterostilbene compound e kōkua i ka hoʻonui ʻana i ka naʻau o ka insulin. He aha a Pterostilbene e hana ai e kāpae i ke kaʻina o ka hoʻololi ʻana i nā puna i loko o nā momona. Ke pale aku nei i nā nui momona mai nā ulu a me ka hoʻonui.

Hoʻololi ʻo Pterostilbene hoʻi i ka hana o ka flora i loko o ka ʻōpū a kōkua i ke kahe ʻana o ka meaʻai.

ʻO nā Rodents i hānai ʻia me Pterostilbene i ʻoi a me ka nui o ka momona flora a he hoʻoikaika nui i Akkermansia muciniphila. ʻO A. muciniphila he mau huaʻōlelo i ʻike ʻia e pale aku i ka maʻi haʻahaʻa, hina, a me ka maʻi maʻi maʻi maʻi. Ua lilo kēia bacteria i ka manaʻo nui o ka noiʻi probiotic i kēia manawa.

iiiii. Hoʻolako ʻo Pterostilbene i ka lōʻihi

ʻO nā pono pterostilbene anti kahiko e hoʻopili ʻia me kahi lāʻau bioactive i kapa ʻia ʻo Trans-pterostilbene. Ua hōʻoia ʻia kēia kemikahia e hōʻemi i ka mumū, hoʻokaʻawale ʻana i ka cognitive drop, a hoʻopaʻa i ka kōʻai koko. I ka vivo a me nā haʻawina vitro e kākoʻo i ka pale a Pterostilbene pale a me ka hopena. Ke hana nei kēia ʻano kūlike i ka hoʻoneʻe caloric i ka mimetic, ka mea e hoʻoulu ai i ke kino e hoʻokuʻu i nā biochemical, me ka adiponectin e hoʻolalelima ana i ke kaʻina o ka wā kolo i ka wā e hoʻolaha nei i ka hoʻōla.

Hoʻomaopopo pinepine kēia supplemental anti-aging no ka pale ʻana i nā maʻi pili i ka makahiki, e hoʻonui ai i ke ola. I loko o nā rodents, nā haʻahaʻa haʻahaʻa o kēia mau kemupene i hoʻohaʻahaʻa i nā hōʻailona e pili ana i ka ʻelemakule. Ua hōʻike ʻia ka noiʻi ʻana i ka ʻai nui o nā kumuʻai pterostilbene e like me ka blueberries e lohi i nā pōpilikia olakino e pili ana i ka wā kahiko, ʻo ia hoʻi me ka dementia a me ke kanesa.

pterostilbene-pauku-3

4. Pterostilbene a me resveratrol

ʻAʻohe kanalua ʻo Pterostilbene a me resveratrol e pili pono ana. Ua kapa ʻia ʻo Resveratrol e like me ka kemika bioactive i loko o ka ʻulaʻula ʻulaʻula a me nā hua waina.

Hoʻohālike nā pono olakino o ka resveratrol i nā Pterostilbene a ua komo i ka pale i ka Alzheimer, nā hopena anticancer, ka hoʻonui ʻana o ka ikehu, nā hopena anti-inflammatory, nā pale anti-diabetes, a me nā pono cardiovascular.

Pterostilbene like me ka kemika e like me ka resveratrol, akā ua hōʻike mua nā noiʻi ʻoi ʻoi aku ka ikaika o Pterostilbene ma mua o ka resveratrol i ka hoʻokele ʻana i kekahi mau kūlana olakino. Ua hōʻike ʻo Pterostilbene i ka nui o ka hoʻonui ʻana i ka hana cognitive, ke ola olakino, a me ka pae o ka glucose.

ʻO ka hapalua ola ʻo Pterostilbene kahi pōkole ma mua o ka hapalua o ke ola o resveratrol. ʻO Pterostilbene maoli mau manawa e wikiwiki e hele i ke aihue ʻana i loko o ke kino ma mua o ka resveratrol. I ka manawa maʻamau, hiki i kēia ke hana i ka Pterostilbene i ʻoi aku ka maikaʻi ma mua o ka resveratrol. Eia nō naʻe, pono e ʻike ʻia nā haʻawina e hōʻoia i kēia.

ʻO ka Pterostilbene a me resveratrol kekahi manawa i hoʻohui pū ʻia e hāʻawi i kahi hoʻohui hoʻohui i loko o ke ʻano o ka capsule. ʻO ka hoʻohui hoʻohui ʻia e lilo i mea ikaika i ka ʻoi o ke kō ʻana o nā pōpoli ʻelua.

5. Hoʻohui ʻia Pterostilbene

ʻAʻohe mea kānalua i hiki ai ke hoʻokō i nā pōmaikaʻi makemake loa o Pterostilbene, ua makemake ʻia e lawe ʻoe ia e like me ka pauku aʻoaʻo. Hoʻohui ʻia Pterostilbene Ke kūʻai ʻia nei i nā hale kūlohelohe kūlohelohe a ma nā hale kūʻai pūnaewele e loea i nā mea hoʻohui meaʻai. Hiki iāʻoe ke loaʻa i nā mea hana pterostilbene ma ka pūnaewele.

Loaʻa ka Pterostilbene supplemental i ka nui o nā capsules form, me ka nui o nā ʻano like ʻole. Pono ʻoe e heluhelu i ka lepili a i ka lepili a hoʻomaopopo i ka nui o Pterostilbene i loko o kēlā me kēia pahu i mua o ke kūʻai. He mea koʻikoʻi kēia no ka mea, e hōʻike paha nā ʻano like ʻole i nā hopena like ʻole.

Eia kekahi, ʻoi aku ka nui o nā pterostilbene supplementation ʻoi aku ke kiʻekiʻe ma mua o nā mea i noiʻi ʻia i loko o nā kanaka. ʻO nā pāʻina hoʻohana pinepine ʻia ma waena o 50 mg a me 1,000 mg o kēlā me kēia kapsul.

E like me ka mea i hōʻike mua ʻia, loaʻa pū nā hoʻohui hoʻohui, me ka hoʻonaninani kaulana ʻana ʻo Pterostilbene a me resveratrol. Hoʻohui pū ʻia ʻo Pterostilbene me ka curcumin, kaʻaila kākā, astragalus, a me nā mea ʻike maoli.

Hiki iā ʻoe ke loaʻa nā ʻōmole sunblock i loaʻa Pterostilbene ʻoiai naʻe maʻa iki. ʻAʻole i aʻo ʻia ka nui o Pterostilbene e pale aku iā ʻoe e kū'ē i ka maʻi ʻili o ka ʻili, akā hiki iā ia ke hāʻawi i ka pale aku.

6. Aia i hea ke ʻike ai i ka pauku maikaʻi loa ʻo Peterostilbene?

Inā ʻoe e ʻimi nei i kahi paila pterostilbene kiʻekiʻe kiʻekiʻe no ke kūʻai ʻana, a laila ma kahi kūpono. ʻO mākou kekahi o nā mea hana kaulana, ʻike a loaʻa i nā mea ulu pterostilbene i Kina. Hāʻawi mākou i nā huahana maʻemaʻe a maikaʻi hoʻi e hoʻomaʻamaʻa ʻia ʻia e ka ʻenehana koleke hoʻomalu honua honua e hōʻoia i ka maʻemaʻe a me ka palekana. Mālama mākou i nā kauoha i ka US, Europe, Asia, a me nā ʻāpana o ka honua. No laila inā makemake ʻoe e kūʻai i ka pauma pterostilbene o ka mea pono loa kiʻekiʻe loa, e kelepona mai iā mākou i kēia manawa.

E hoʻomaopopo '

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  3. Ka palekana o ka synthetic trans ‐ resveratrol ma ke ʻano he kīpē ʻĀina e like me ke Kānāwai (EC) No 258/97 ″. Hōʻike Pūnaewele EFSA. E pili ana i ka Mana Hoʻomaʻi Meaʻai ʻEulopa, ka Panel EFSA ma nā huahana Dietetic, kaʻai a me ka maʻi āpau. 14 (1): 4368
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